Results 61 to 70 of about 629,370 (259)

Use of alfacalcidol in osteoporotic patients with low muscle mass might increase muscle mass: An investigation using a patient database [PDF]

Geriatrics & Gerontology International, 2014
AimSarcopenia causes a decline in physical performance and decreased quality of life. However, there is little evidence for effective treatments. Because of the similarities between osteoporosis and sarcopenia, alfacalcidol used for osteoporosis might be beneficial for low muscle mass.
Sadayuki, Ito, Atsushi, Harada, Takehiro, Kasai, Yoshihito, Sakai, Marie, Takemura, Yasumoto, Matsui, Tetsuro, Hida, Naoki, Ishiguro   +7 more
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Effects of inactivity on human muscle glutathione synthesis by a double-tracer and single-biopsy approach

, 2010
Oxidative stress is often associated to inactivity-mediated skeletal muscle atrophy. Glutathione is one of the major antioxidant systems stimulated, both at muscular and systemic level, by activation of oxidative processes.
DALLA LIBERA L, Francesco Agostini, Biolo, Gianni, JURDANA M, Mihaela Jurdana, Sara Mazzucco, BIOLO G., Agostini, Francesco, Jörn Rittweger, Mazzucco, Sara, Jurdana, Mihaela, Luciano Dalla Libera, Narici, Marco, Gianni Biolo, Dalla Libera, Luciano, NARICI M, MEKJAVIC IB, Rittweger, Jörn, AGOSTINI F, Igor B. Mekjavic, Pisot, Rado, PISOT R, Mekjavic, Igor, MAZZUCCO S, Gorza, Luisa, Rado Pišot, RITTWEGER J, Marco Narici, Luisa Gorza, Gorza L   +29 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients [PDF]

[Background] Sarcopenia is a major health issue especially in patients on maintenance hemodialysis. Low skeletal muscle mass is included in the diagnostic criteria for sarcopenia.
26959, Taniguchi, Munehiro, Isomoto, Hajime, Iyama, Takuji, 26972, 1082, Hamada, Shintaro, Ida, Ayami, 26970, 26971, 90322304, Motoe, Aki, タカタ, トモアキ, 磯本, 一, 3618, Yamada, Kentaro, ヤマダ, ケンタロウ, 26969, 26962, 26961, 26964, タニグチ, ソウスケ, Taniguchi, Sosuke, 26963, 26966, 26965, 100001163, 26968, イソモト, ハジメ, 26967, 高田, 知朗, 100001541, Yamamoto, Marie, Mae, Yukari, Tanida, Katsumi, Nakaoka, Akihisa, 26960, Takata, Tomoaki, Ogawa, Masaya   +38 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Muscle mass and association to quality of life in non-small cell lung cancer patients [PDF]

, 2017
Background Cancer wasting is characterized by muscle loss and may contribute to fatigue and poor quality of life (QoL). Our aim was to investigate associations between skeletal muscle index (SMI) and skeletal muscle radiodensity (SMD) and selected QoL ...
Bjørn H. Grønberg, Aass, Nina Kathrine, Vickie E. Baracos, Wentzel-Larsen, Tore, Baracos, Vickie Elaine, Jordhøy, Marit Slaaen, Hjermstad, Marianne Jensen, Bjørg Sjøblom, Sjøblom, Bjørg, Tore Wentzel-Larsen, Grønberg, Bjørn Henning, Øystein Fløtten, Nina Aass, Baracos, Vickie E., Marianne J. Hjermstad, Fløtten, Øystein, Asta Bye, Bye, Asta, Bremnes, Roy M., Roy M. Bremnes, Marit Jordhøy   +20 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Sarcopenia and change in body composition following maximal androgen suppression with abiraterone in men with castration-resistant prostate cancer. [PDF]

, 2013
BACKGROUND: Standard medical castration reduces muscle mass. We sought to characterize body composition changes in men undergoing maximal androgen suppression with and without exogenous gluocorticoids.
J S de Bono, Pezaro, C., Cassidy, A.M., de Bono, J.S., Pezaro, C, Seed, G., Mukherji, D, de Bono, JS, Omlin, A, Tunariu, N., N Tunariu, G Attard, D Olmos, Attard, G, G Seed, Reid, A.H.M., Seed, G, Mukherji, D., A M Cassidy, Bianchini, D., Cassidy, AM, Olmos, D., A H M Reid, Attard, G., A Omlin, D Bianchini, D Mukherji, Tunariu, N, Olmos, D, Reid, AHM, C Pezaro, Bianchini, D, Omlin, A.   +32 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source