Results 131 to 140 of about 16,392,537 (299)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Evidence for Lower Critical Solution Behavior in Ionic Liquid Solutions

open access: yes, 2016
Lower critical solution temperatures (LCST)-type of phase diagrams, including the presence of closed loops, have been encountered for the first time in binary and quasi-binary liquid solutions of ionic liquids.
Henrique J. R. Guedes (2520364)   +7 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Electrochemical Corrosion and Critical Pitting Temperature of S32750 Super Duplex Stainless Steel in NaCl Solution

open access: yes, 2015
The electrochemical corrosion behavior and critical pitting temperature (CPT)of S32750 super duplex stainless steel in 3.5%NaCl solution were investigated by electrochemical techniques.
Yang Lijing   +5 more
core  

H2S-Responsive Lower Critical Solution Temperature of the Host-Guest Complex Based on Oxatub[4]arene with Tri(ethylene oxide) Moieties

open access: yes, 2017
A water-soluble oxatub[4]arene with tri(ethylene oxide) moieties was synthesized. The lower critical solution temperature (LCST) behavior of this macrocyclic receptor was tunable by changing its concentration or by adding an appropriate guest.
Liu, Hao   +4 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Reversibly Tunable Lower Critical Solution Temperature Behavior Induced by H‑Bonded Aromatic Amide Macrocycle and Imidazolium Host–Guest Complexation

open access: yes, 2016
A new supramolecular host–guest motif comprising an H-bonded aromatic amide macrocycle and imidazolium cation based ionic liquids was developed, which allows tunable binding affinity via altering N-substitution or counterions.
Lihua Yuan (101854)   +7 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

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