Results 141 to 150 of about 16,392,537 (299)

The effect of graphene on the lower critical solution temperature of poly(N-isopropylacrylamide)

, 2013
N-isopropylacrylamide is grafted on graphene by free radical polymerization to produce a series of graphene-poly(N-isopropylacrylamide) (PNIPAM) hybrid materials with different contents of graphene.
戴李宗, Weng, Jian, Dong, Jun, Dai, Lizong   +3 more
core  

Atomistic Molecular Dynamics Simulations of the Lower Critical Solution Temperature Transition of Poly(N‑vinylcaprolactam) in Aqueous Solutions

, 2019
Poly­(N-vinylcaprolactam) (PVCL) is a thermo-responsive polymer, which exhibits a lower critical solution temperature (LCST) in an aqueous solution. The LCST of this hydrophilic-to-hydrophobic transition is found to be strongly dependent on the salt-type
Xiaoquan Sun (2521537), Xianghong Qian, Xiaoquan Sun, Xianghong Qian (1270104)   +3 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Temperature-independent and photocrosslinkable hydrolyzed GelMA with tunable mechanics for biofabrication

Materials Today Bio
Thermoresponsive and photo-crosslinkable hydrogels are highly desirable for biofabrication; however, conventional gelatin methacryloyl (GelMA) exhibited thermal gelation below 30 °C and high viscosity, restricting its compatibility with concentration ...
JuneHyun Kyeong, Dayi Jeong, Hojae Bae
doaj   +1 more source

Tuning the pore structure of poly(vinylidene fluoride) membrane for efficient oil/water separation: A novel vapor-induced phase separation method based on a lower critical solution temperature system

, 2020
Tuning the pore structure of poly(vinylidene fluoride) membrane for efficient oil/water separation: A novel vapor-induced phase separation method based on a lower critical solution temperature ...
X Yang (5161994), N Long (7805276), T Xiao (13326240), W Chen (774826)   +3 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Upper and Apparent Lower Critical Solution Temperature Branches in the Phase Diagram of Polymer:Small Molecule Semiconducting Systems

Solution-processable semiconducting materials are complex materials with a wide range of applications. Despite their extensive study and utility, their molecular interactions as manifested, for example, in phase behavior are poorly understood.
Nrup Balar (3190872), Harald Ade (1273878), Masoud Ghasemi (3190866), Zhengxing Peng (4246993)   +3 more
core   +1 more source