Results 51 to 60 of about 16,392,537 (299)

Lower critical solution temperature (LCST) phase behaviour of an ionic liquid and its control by supramolecular host–guest interactions [PDF]

, 2016
Lower critical solution temperature (LCST) phase behaviour of an imidazolium- based ionic liquid is reported, which can be controlled by concentration, the choice of cation, anion and solvent, and by supramolecular host–guest complex formation. Molecular
Yuan, Jiayin, Schalley, Christoph A., Heyda, J., Schalley, C., Dong, S., Yuan, J., Heyda, Jan, Dong, Shengyi   +7 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Thermoresponsive copolymer-grafted SBA-15 porous silica particles for temperature-triggered topical delivery systems

eXPRESS Polymer Letters, 2017
A series of poly(N-isopropylacrylamide-co-acrylamide) thermoresponsive random copolymers with different molecular weights and composition were synthesized and characterized by attenuated total reflectance Fourier-transform infrared (ATR-FTIR ...
S. A. Jadhav, D. Scalarone, V. Brunella, E. Ugazio, S. Sapino, G. Berlier   +5 more
doaj   +1 more source

Hydration and Dynamic Behavior of Poly(N-isopropylacrylamide)s in Aqueous Solution:  A Sharp Phase Transition at the Lower Critical Solution Temperature

, 2016
The number of hydrated water molecules per poly(N-isopropylacrylamide) monomer unit in homogeneous aqueous solution was determined to be 11 exactly and anew below the lower critical solution temperature of 32 °C employing high-frequency dielectric ...
Toshiyuki Shikata (2098252), Yousuke Ono (2532313)   +1 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Branched Copolymer Surfactants as Versatile Templates for Responsive Emulsifiers with Bespoke Temperature‐Triggered Emulsion‐Breaking or Gelation

Advanced Materials Interfaces
It has been found that the thermoresponsive behavior of emulsions stabilized by block copolymer surfactants (BCSs) can induce either gelation or emulsion break‐up with mild temperature changes.
Abhishek Rajbanshi, Marcelo Alves da Silva, Niamh Haslett, Philippa Cranwell, Neil Cunningham, Najet Mahmoudi, Darragh Murnane, Ewa Pavlova, Miroslav Slouf, Cecile Dreiss, Michael Cook   +10 more
doaj   +1 more source

Entropy Rules: Molecular Dynamics Simulations of Model Oligomers for Thermoresponsive Polymers

Entropy, 2020
We attempted to attain atomic-scale insights into the mechanism of the heat-induced phase transition of two thermoresponsive polymers containing amide groups, poly(N-isopropylacrylamide) (PNIPAM) and poly(2-isopropyl-2-oxazoline) (PIPOZ), and we ...
Alexander Kantardjiev, Petko M. Ivanov
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Thickness-Dependent Swelling Behavior of Vapor-Deposited Hydrogel Thin Films

Proceedings, 2018
Hydrogel thin films containing temperature sensitive chemical functionalities (such as N-isopropylacrylamide, NIPAAm) are particularly interesting for sensor and actuator setups.
Fabian Muralter, Alberto Perrotta, Anna Maria Coclite   +2 more
doaj   +1 more source