Results 71 to 80 of about 16,392,537 (299)

Hydrophobic Interaction Model for Upper and Lower Critical Solution Temperatures [PDF]

Macromolecules, 2003
11 pages, 7 figures, to be published in ...
Moelbert, Susanne, De Los Rios, Paolo
openaire   +3 more sources

Nonionic Cyclodextrin Based Binary System with Upper and Lower Critical Solution Temperature Transitions via Supramolecular Inclusion Interaction

, 2016
A nonionic binary aqueous interaction system consisting of β-cyclodextrin trimer (β-CD3) and naphthalene-terminated poly­(ethylene glycol) (PEG-NP2), which has tunable upper critical solution temperature (UCST) behavior around room temperature and lower ...
Haitao Zhang (47756), Yang Bai (198601), Xiaodong Fan (1785997), Zhen Yang (107412), Wei Tian (291921), Dan Wang (34472)   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Conjugates of methylated cyclodextrin derivatives and hydroxyethyl starch (HES): Synthesis, cytotoxicity and inclusion of anaesthetic actives

Beilstein Journal of Organic Chemistry, 2014
The mono-6-deoxy-6-azides of 2,6-di-O-methyl-β-cyclodextrin (DIMEB) and randomly methylated-β-cyclodextrin (RAMEB) were conjugated to propargylated hydroxyethyl starch (HES) by Cu+-catalysed [2 + 3] cycloaddition.
Lisa Markenstein, Antje Appelt-Menzel, Marco Metzger, Gerhard Wenz   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Lower Critical Solution Temperature in the Metastable Region of an Ionic Solution in a Non-Polar Solvent

, 2016
Previous studies of the critical behavior of ionic solutions in nonpolar solvents showed mainly upper critical solution temperatures. Now, we report for the solution of tetra-n-butyl ammonium bromide (N4444Br) in toluene a nearly closed miscibility loop,
Harro R. Dittmar (2394262), Wolffram H. Schröer (2394265)   +1 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

pH-sensitive tunable thermochromic hydrogel with carbon quantum dots for smart windows

National Science Open
Thermoresponsive hydrogels have been designed for smart windows to dynamically modulate solar radiation, but their inherent drawbacks of long response time and imperfectly matched phase transition temperature have limited their wide applications.
Zhong Sai, Xue Yuxuan, Wang Kuanwen, Li Haoyang, Lu Yanghua, Pang Zhenqian, Jiang Tengyao, Tan Gang   +7 more
doaj   +1 more source

A Fluorescent Thermometer Based on a Pyrene-Labeled Thermoresponsive Polymer

Sensors, 2010
Thermoresponsive polymers that undergo a solubility transition by variation of the temperature are important materials for the development of ‘smart’ materials.
Ulrich S. Schubert, Richard Hoogenboom, Christian Pietsch, Antje Vollrath   +3 more
doaj   +1 more source