Results 91 to 100 of about 1,978,744 (337)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Conjugates of methylated cyclodextrin derivatives and hydroxyethyl starch (HES): Synthesis, cytotoxicity and inclusion of anaesthetic actives

open access: yesBeilstein Journal of Organic Chemistry, 2014
The mono-6-deoxy-6-azides of 2,6-di-O-methyl-β-cyclodextrin (DIMEB) and randomly methylated-β-cyclodextrin (RAMEB) were conjugated to propargylated hydroxyethyl starch (HES) by Cu+-catalysed [2 + 3] cycloaddition.
Lisa Markenstein   +3 more
doaj   +1 more source

Polyester textile functionalization through incorporation of pH/thermo-responsive microgels. Part II: polyester functionalization and characterization [PDF]

open access: yes, 2011
A new approach to functionalize the surface of polyester textiles is described in this study. Functionalization was achieved by incorporating pH/temperature-responsive polyelectrolyte microgels into the textile surface layer using UV irradiation. The aim
Calvimontes, A.   +3 more
core   +5 more sources

Lower Critical Solution Temperature in Aqueous Solutions of N-Alkyl-Substituted Polyacrylamides [PDF]

open access: yesPolymer Journal, 1999
The structures and properties of N-alkyl-substituted polyacrylamides (PAA) were studied by FT-IR spectroscopy. For N-alkyl-substituted PAA with lower critical solution temperature (LCST), a specific H-bonded cyclic structure involving alkyl amide units of a polymer and hydroxyl functions of water was observed and found responsible for polymer ...
Nikolai A Platé   +2 more
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

pH-sensitive tunable thermochromic hydrogel with carbon quantum dots for smart windows

open access: yesNational Science Open
Thermoresponsive hydrogels have been designed for smart windows to dynamically modulate solar radiation, but their inherent drawbacks of long response time and imperfectly matched phase transition temperature have limited their wide applications.
Zhong Sai   +7 more
doaj   +1 more source

End-group functionalization of poly(2-oxazoline)s using methyl bromoacetate as initiator followed by direct amidation [PDF]

open access: yes, 2019
Poly(2-alkyl/aryl-2-oxazoline)s (PAOx) are an alluring class of polymers for many applications due to the broad chemical diversity that is accessible for these polymers by simply changing the initiator, terminating agent and the monomer(s) used in their ...
Arys, Koen   +4 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Synthesis and Characterization of New Functional Photo Cross-Linkable Smart Polymers Containing Vanillin Derivatives

open access: yesGels, 2016
The synthesis of new functional monomers based on vanillin is reported. The monomers further were used in the synthesis of different temperature-responsive photo cross-linkable polymers via free radical polymerization with N-isopropyl acrylamide and a ...
Momen S.A. Abdelaty, Dirk Kuckling
doaj   +1 more source

Thermo-Reversible Gelation of Aqueous Hydrazine for Safe Storage of Hydrazine

open access: yesTechnologies, 2020
A reversible gelation–release system was developed for safe storage of toxic hydrazine solution based on gelation at lower critical solution temperature (LCST).
Bungo Ochiai, Yohei Shimada
doaj   +1 more source

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