Results 101 to 110 of about 16,392,537 (299)
Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016 Phase transitions of protein solutions which are of interest for biotechnological and biomedical purposes should be analyzed from the point of view of their interrelation with phase transitions of the structure of protein molecules on the basis of the ...
Sergey Rozhkov
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Thermosensitive polymers in drug delivery systems (review)
Разработка и регистрация лекарственных средствIntroduction. Water-soluble polymers that are sensitive to temperature are promising for use in pharmaceutical development to create "smart" drug delivery systems.Text.
D. O. Maslov, M. S. Zolotareva
doaj +1 more source
, 2015 Water-miscible ionic liquids (ILs) may be salted out using kosmotropic salts such as potassium phosphate (K3PO4) to form salt-salt aqueous biphasic systems (ABS).
Pereira, Jorge Fernando Brandão [UNESP] +5 more
core +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
PROTEIN SOLUTION PHASE DIAGRAMS AND PROTEIN MOLECLUE STRUCTURAL TRANSITIONS
Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016 An analysis of standard thermodynamic functions of protein structure in solution allows revealing important features of protein solution phase behavior, particularly the presence of higher and lower critical solution temperatures on phase diagram (PD ...
Sergey Rozhkov, Andrey Goryunov
doaj +1 more source
, 2016 A thermoresponsive macromolecule consisting of 10 outer triethylene oxide groups and a pillar[5]arene core was prepared. The macromolecule showed lower critical solution temperature behavior. Moreover, its clouding point can be reversibly tuned based on
Tomoki Ogoshi (1269234) +2 more
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
, 2019 Although the gelation process and lower critical solution temperature (LCST) behavior are well acknowledged in polymer systems, low-molecular-weight gelators (LMWGs) rarely display LCST behavior during supramolecular gelation.
Shuanggen Wu +13 more
core +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source