Results 101 to 110 of about 1,978,744 (337)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

An amphiphilic pseudo[1]catenane: neutral guest-induced clouding point change

Beilstein Journal of Organic Chemistry, 2018
The hydrophobic/hydrophilic ratio in a molecule largely affects its assembled properties in aqueous media. In this study, we synthesized a new bicyclic compound which could dynamically change its hydrophobic/hydrophilic ratio by chemical stimulus.
Tomoki Ogoshi, Tomohiro Akutsu, Tada-aki Yamagishi   +2 more
doaj   +1 more source

Critical Phenomena in Continuous Dimension [PDF]

, 2003
We present a calculation of critical phenomena directly in continuous dimension d employing an exact renormalization group equation for the effective average action.
Aoki, Berges, C. Wetterich, Canet, H. Ballhausen, J. Berges, Kleinert, Kleinert, Li, Litim, Morris, Tissier, von Gersdorff, Wetterich, Wetterich, Wilson, Zinn-Justin   +16 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Advances in thermo-responsive polymers exhibiting upper critical solution temperature (UCST)

eXPRESS Polymer Letters, 2019
Immense work has been conducted in the field of thermoresponsive polymers specifically of lower critical solution temperature (LCST) type, but upper critical solution temperature (UCST) type polymers remain a significantly unexplored domain.
K. K. Bansal, P. K. Upadhyay, G. K. Saraogi, A. Rosling, J. M. Rosenholm   +4 more
doaj   +1 more source

モノアザテトラチオエーテルを含有する温度感応性高分子による銀(I)イオンの抽出挙動 [PDF]

, 2008
A novel temperature sensitive extraction copolymers, 9-aza-3,6,12,15-tetrathiaheptadecane-derivatized N-isopropylacrylamide polymer (ATH-NIPAAm), has been synthesized in various incorporation ratios.
Kenji Chayama, Satoshi IWATSUKI, Yoshiaki Morita, 岩月 聡史, 森田 吉亮, 茶山 健二   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Phase Behavior and Heat Capacity of {DPnP + Water} Mixtures at the Temperature Range of 273.15–338.15 K

Journal of Chemistry, 2015
The differential scanning calorimetry method (DSC) was used to examine the miscibility in the {dipropylene glycol propyl ether (DPnP) + water} system.
Mariola Tkaczyk, Henryk Piekarski, Paweł Góralski   +2 more
doaj   +1 more source

Superconductivity at 23 K in Pt doped BaFe2As2 single crystals

, 2010
We report superconductivity in single crystals of the new iron-pnictide system BaFe1.9Pt0.1As2 grown by a self-flux solution method and characterized via x-ray, transport, magnetic and thermodynamic measurements.
Alireza P L, Bud’ko S L, Cheng P, Johnpierre Paglione, K Kirshenbaum, Li L J, N P Butch, P Y Zavalij, Park T, Ren Z-A, S R Saha, Saha S R, T Drye, Wang X F, Zhu X   +14 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source