Results 61 to 70 of about 16,392,537 (299)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
GelsGold nanoparticles (AuNPs) possess attractive electronic, optical, and catalytic properties, enabling many potential applications. Poly(N-isopropyl acrylamide) (PNIPAAm) is a temperature-responsive polymer that changes its hydrophilicity upon a slight ...
Palida Pongsanon +3 more
doaj +1 more source
LCST phase behavior of benzo-21-crown-7 with different alkyl chains
Beilstein Journal of Organic Chemistry, 2019 The introduction of hydrophobic units into crown ethers can dramatically decrease the critical transition temperature of LCST and realize macroscopic phase separation at low to moderate temperature and concentration.
Yan Deng +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular insight into the lower critical solution temperature transition of aqueous alkyl phosphonium benzene sulfonates [PDF]
, 2019 Ionic liquid (IL)-water mixtures can exhibit a lower critical solution temperature (LCST) transition, but changes in long-range order and local molecular environment during this transition are not comprehensively understood.
Kang, Hyungmook +5 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
, 2016 Side-Chain Polypseudorotaxanes with Heteromacrocyclic Receptors of Cyclodextrins (CDs) and Cucurbit[7]uril (CB7): Their Contrast Lower Critical Solution Temperature Behavior with α-CD, γ-CD, and ...
Tomoki Ogoshi (1269234) +3 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2020 In this work, liquid–liquid equilibrium (LLE) data at different temperatures have been correlated for 30 binary systems that presented different miscibility behaviors: 15 upper critical solution temperature (UCST), 5 lower critical solution temperature ...
Marina Trives (8708622) +4 more
core +2 more sources
Biological ControlTo enhance in-soil survival the field stability and environmental responsiveness of traditional microbial biocontrol agents, this study developed a thermosensitive immobilized Bacillus subtilis formulation, S24, by combining a biochar-based carrier with ...
Yaqi Fu +6 more
doaj +1 more source