Results 61 to 70 of about 1,776,297 (283)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

LCST phase behavior of benzo-21-crown-7 with different alkyl chains

Beilstein Journal of Organic Chemistry, 2019
The introduction of hydrophobic units into crown ethers can dramatically decrease the critical transition temperature of LCST and realize macroscopic phase separation at low to moderate temperature and concentration.
Yan Deng, Xing Li, Qiao Zhang, Zheng Luo, Chengyou Han, Shengyi Dong   +5 more
doaj   +1 more source

Polyester textile functionalization through incorporation of pH/thermo-responsive microgels. Part II: polyester functionalization and characterization [PDF]

, 2011
A new approach to functionalize the surface of polyester textiles is described in this study. Functionalization was achieved by incorporating pH/temperature-responsive polyelectrolyte microgels into the textile surface layer using UV irradiation. The aim
Calvimontes, A., Dutschk, V., Glampedaki, P., Warmoeskerken, M.M.C.G.   +3 more
core   +5 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Effect of Gold Nanoparticle Size on Regulated Catalytic Activity of Temperature-Responsive Polymer−Gold Nanoparticle Hybrid Microgels

Gels
Gold nanoparticles (AuNPs) possess attractive electronic, optical, and catalytic properties, enabling many potential applications. Poly(N-isopropyl acrylamide) (PNIPAAm) is a temperature-responsive polymer that changes its hydrophilicity upon a slight ...
Palida Pongsanon, Akifumi Kawamura, Hideya Kawasaki, Takashi Miyata   +3 more
doaj   +1 more source

The Removal of Hydrophobic Matter from Thermosensitive Poly[oligo(ethylene glycol) Monomethyl Ether Acrylate] Gel Adsorbent in Alcohol–Water Mixtures

Gels, 2022
A thermosensitive gel that exhibits lower critical solution temperature (LCST) becomes hydrophilic at low temperatures and hydrophobic at high temperatures in water.
Syed Ragib Safi, Toshiki Kaneko, Katsuhiro Nakahara, Takehiko Gotoh, Takashi Iizawa   +4 more
doaj   +1 more source

The encapsulation of hydrophobic drugs in Pluronic F127 micelles: the effects of drug hydrophobicity, solution temperature and pH

, 2013
Three drugs, Ibuprofen, Aspirin and Erythromycin, are encapsulated in spherical Pluronic F127 micelles. The shapes and the size distributions of the micelles in dilute, aqueous solutions, with and without drugs, are ascertained using cryo- Scanning ...
Bandyopadhyay, Ranjini, Basak, Rajib
core   +1 more source

Phase Equilibria of Lattice Polymers from Histogram Reweighting Monte Carlo Simulations [PDF]

, 1997
Histogram-reweighting Monte Carlo simulations were used to obtain polymer / solvent phase diagrams for lattice homopolymers of chain lengths up to r=1000 monomers.
Floriano, M. Antonio, Panagiotopoulos, Athanassios Z., Wong, Vicky   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Thermosensitive core-rigid micelles of monomethoxy poly(ethylene glycol)-deoxy cholic acid

Biomaterials Research, 2022
Background Thermosensitive micelles with rigid cores that exhibit a reversible lower critical solution temperature at 30–35 °C can be applied for drug delivery.
Jin Ok Han, Hyun Jung Lee, Byeongmoon Jeong   +2 more
doaj   +1 more source