Mechanical Stiffening Promotes Growth, Invasion-Associated Phenotypes, and Reduced Selumetinib Sensitivity in 3D Plexiform Neurofibroma Cultures. [PDF]
Ji K, Shi C, Zhang J, Mattingly RR.
europepmc +1 more source
Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu +5 more
wiley +1 more source
Reconstructing protein conformations to activate follicular enzyme-nutrient reservoirs for reversing follicle aging. [PDF]
Ling S +9 more
europepmc +1 more source
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du +7 more
wiley +1 more source
Degradation of LOX-1 via Neuronal Autophagy Alleviates Cerebral Ischemia/Reperfusion Injury in Mice. [PDF]
Hu Y +7 more
europepmc +1 more source
This study presents a comprehensive evaluation of Hibiscus sabdariffa L. calyx extracts from Libya, integrating phytochemical profiling, multi‐target biological activities, and in silico validation. Aqueous and ethanolic extracts were prepared and assessed for antibacterial activity against multidrug‐resistant clinical isolates (MIC: 6.25–25 mg/mL; MBC/
Ahmed Saeed Kabbashi +8 more
wiley +1 more source
Enhanced Anti-Atherogenic Effects of Epicatechin and Hydroxytyrosol in THP-1 Macrophages: An Integrated In Silico and In Vitro Study. [PDF]
Bashanfar NO +3 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Synthesis, Characterization, and Cytotoxic Activity Properties of Some Novel Purine Derivatives. [PDF]
Akdoğan N +6 more
europepmc +1 more source
Screening and mechanistic evaluation of antioxidants for mitigating beany flavor formation during pea protein isolation. [PDF]
Villacís-Chiriboga J +4 more
europepmc +1 more source

