Results 21 to 30 of about 97,118 (179)

Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients [PDF]

PeerJ, 2020
Head and neck squamous cell carcinoma (HNSCC) represents a significant world health problem, with approximately 600,000 new cases being diagnosed annually. The prognosis for patients with HNSCC is poor and, therefore, the identification of biomarkers for
Mariati Abdul Rahman, Didi Erwandi Mohamad Haron, Robert J. Hollows, Zuleen Delina Fasya Abdul Ghani, Mustafa Ali Mohd, Wen Lin Chai, Ching Ching Ng, Munn Sann Lye, Saiful Anuar Karsani, Lee Fah Yap, Ian C. Paterson   +10 more
doaj   +2 more sources

Non-Edg family LPA receptors: the cutting edge of LPA research [PDF]

Journal of Biochemistry, 2011
Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and pathological actions on many types of cells. Originally, LPA was thought to elicit its biological functions through three subtypes of endothelial differentiation gene (Edg) family G protein-coupled receptors (LPA1, LPA2 and LPA3) until our group identified a fourth
Keisuke, Yanagida, Satoshi, Ishii
openaire   +2 more sources

Lysophosphatidic Acid Receptor 5 (LPA₅) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro

Cells, 2022
Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is continuously monitored by microglia. In the CNS, these changes include increased synthesis of the bioactive lipid lysophosphatidic acid (LPA), a ligand for the
Lisha Joshi, Ioanna Plastira, Eva Bernhart, Helga Reicher, Zhanat Koshenov, Wolfgang F. Graier, Nemanja Vujic, Dagmar Kratky, Richard Rivera, Jerold Chun, Wolfgang Sattler   +10 more
doaj   +1 more source

Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers. [PDF]

PLoS ONE, 2014
Lysophosphatidic acid (LPA) is a natural bioactive lipid with growth factor-like functions due to activation of a series of six G protein-coupled receptors (LPA₁₋₆).
Marion David, Debashish Sahay, Florence Mege, Françoise Descotes, Raphaël Leblanc, Johnny Ribeiro, Philippe Clézardin, Olivier Peyruchaud   +7 more
doaj   +1 more source

Cross-sectional associations between sleep duration, sedentary time, physical activity, and adiposity indicators among Canadian preschool-aged children using compositional analyses [PDF]

, 2017
Background Sleep duration, sedentary behaviour, and physical activity are three co-dependent behaviours that fall on the movement/non-movement intensity continuum.
AG LeBlanc, AL Adolph, B Day, BW Timmons, C Rich, Canadian Society for Exercise Physiology, CE Boeke, CJ Dobbelsteyn, DP Cliff, JNK Rao, KA Pfeiffer, KF Rust, L Matricciani, LL Moore, M Hirshkowitz, M Kang, Mark S. Tremblay, ME Rosenberger, MF Rolland-Cachera, ML Louzada, MP Buman, MS Tremblay, MS Tremblay, MS Tremblay, MS Tremblay, National Institutes of Health, RA Jones, RC Colley, RC Colley, RP Troiano, S Paruthi, Sebastien F. M. Chastin, SF Chastin, SL Wong, SM Williams, Statistics Canada, T Hinkley, V Carson, V Espana-Romero, Valerie Carson, WHO Multicentre Growth Reference Study Group, X Chen, Z Pedisic   +42 more
core   +4 more sources

Testing the ICD-11 proposal for complex PTSD in trauma-exposed adults: factor structure and symptom profiles

European Journal of Psychotraumatology, 2018
Background: The proposed ICD-11 criteria for trauma-related disorders define posttraumatic stress disorder (PTSD) and complex posttraumatic stress disorder (cPTSD) as separate disorders.
Maria Böttche, Thomas Ehring, Antje Krüger-Gottschalk, Heinrich Rau, Ingo Schäfer, Julia Schellong, Anne Dyer, Christine Knaevelsrud   +7 more
doaj   +1 more source

Antisymmetric and other subleading corrections to scaling in the local potential approximation [PDF]

, 2001
For systems in the universality class of the three-dimensional Ising model we compute the critical exponents in the local potential approximation (LPA), that is, in the framework of the Wegner-Houghton equation.
Bagnuls, Bagnuls, Bagnuls, Berges, Berges, Bruce, Comellas, Fodor, Fodor, Halasz, Hasenfratz, Kajantie, Kirzhnits, Kirzhnits, M.M. Tsypin, Newman, Nicoll, Nicoll, Parola, Parola, Pelissetto, Rehr, Rummukainen, Stephanov, Wegner, Wegner, Wilding, Wilding, Wilding, Wilding, Zhang   +30 more
core   +4 more sources

Utility of GeneXpert in Diagnosis of Pediatric Tuberculosis and Detection of Rifampicin Resistance [PDF]

Perspectives In Medical Research
Background: Tuberculosis (TB) remains a significant public health challenge in developing countries, including India, where children under 15 years account for 12% of all TB cases. The National Tuberculosis Elimination Programme (NTEP) recommends the use
Pooja Shah, Sae Pol, Esther Prabhakaran, Bhakti Karmalkar, Vaishali Gaikwad, Sujata Dharamshale, Rajesh Karyakarte   +6 more
doaj   +1 more source

Lysophosphatidic Acid Alters The Expression of Apoptosis Related Genes and miR-22 in Cultured and Autotransplanted Ovaries [PDF]

Cell Journal, 2021
Objective: The aim of this study was to evaluate the effect of lysophosphatidic acid (LPA) on the follicular development, incidence of cell death, and expressions of apoptosis related genes and miR-22 in transplanted ovaries.
Maryam Dehghan, Shirin Shahbazi, Mojdeh Salehnia   +2 more
doaj   +1 more source

Two Acheuleans, two humankinds. From 1.5 to 0.85 Ma at Melka Kunture (Upper Awash, Ethiopian highlands) [PDF]

, 2017
The Acheulean is the longest-lasting human cultural record, spanning approximately 1.5 Ma and three continents. The most comprehensive sequences are found in East Africa, where, in large-scale syntheses, the Lower Pleistocene Acheulean (LPA) has often ...
Gallotti, Rosalia, Mussi, Margherita
core   +1 more source