Results 31 to 40 of about 2,233 (191)

Ligand Radicals Tune LPMO Activity in Model Complex. [PDF]

Inorg Chem
Radicals are essential to the catalytic chemistry of metalloenzymes, enabling reactivity and self-protection through controlled redox processes. In copper-dependent LPMOs, amino acid radicals mediate oxidative transformations via hole hopping. However, the generation and role of ligand-centered radicals in synthetic copper models remain poorly ...
Marques Netto CGC, Pandey R, Bezerra de Castro C, Moreno L, Pereira Ferreira M, Gomes Rodrigues L, Gonçalves Guimaraes W, de Araujo-Neto JH, Conciani G, Dyer RB, Jannuzzi SAV, de Moura AF, Ferreira de Souza DH, Nascimento OR.   +13 more
europepmc   +4 more sources

Inhibition of the Peroxygenase Lytic Polysaccharide Monooxygenase by Carboxylic Acids and Amino Acids

Antioxidants, 2022
Lytic polysaccharide monooxygenases (LPMOs) are widely distributed in fungi, and catalyze the oxidative degradation of polysaccharides such as cellulose.
Erik Breslmayr, Peter Poliak, Alen Požgajčić, Roman Schindler, Daniel Kracher, Chris Oostenbrink, Roland Ludwig   +6 more
doaj   +1 more source

Enhanced in situ H2O2 production explains synergy between an LPMO with a cellulose-binding domain and a single-domain LPMO

Scientific Reports, 2022
Abstract Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that catalyze oxidative depolymerization of recalcitrant substrates such as chitin or cellulose. Recent work has shown that LPMOs catalyze fast peroxygenase reactions and that, under commonly used reaction set-ups, access to in situ ...
Anton A. Stepnov, Vincent G. H. Eijsink, Zarah Forsberg   +2 more
openaire   +3 more sources

Heterologous expression and characterization of novel GH12 β-glucanase and AA10 lytic polysaccharide monooxygenase from Streptomyces megaspores and their synergistic action in cellulose saccharification

Biotechnology for Biofuels and Bioproducts, 2023
Background The combination of cellulase and lytic polysaccharide monooxygenase (LPMO) is known to boost enzymatic saccharification of cellulose. Although the synergy between cellulases (GH5, 6 or 7) and LPMOs (AA9) has been extensively studied, the ...
Xing Qin, Kun Yang, Jiahuan Zou, Xiaolu Wang, Tao Tu, Yuan Wang, Xiaoyun Su, Bin Yao, Huoqing Huang, Huiying Luo   +9 more
doaj   +1 more source

Heterologous expression of lytic polysaccharide monooxygenases (LPMOs)

Biotechnology Advances, 2020
Lytic polysaccharide monooxygenases (LPMOs) are relatively new enzymes that have been discovered 10 years ago. LPMOs comprise a diverse group of enzymes which play a pivotal role in the depolymerization of sugar-based biopolymers including cellulose, hemicellulose, chitin, and starch.
Gaber, Yasser, Rashad, Boshra, Hussein, Rasha, Abdelgawad, Mai, Ali, Nourhan S., Dishisha, Tarek, Varnai, Aniko   +6 more
openaire   +4 more sources

Lysdrevet lytisk polysakkaridmonooksygenase (LPMO)-katalysert løseliggjøring av polysakkarider [PDF]

, 2022
Lytic polysaccharide monooxygenases (LPMOs) are a recently discovered family of enzymes that catalyze oxidative cleavage of glycosidic bonds in insoluble polysaccharides at a liquid-solid interface.
Kommedal, Eirik Garpestad
core  

A fast and sensitive activity assay for lytic polysaccharide monooxygenase

Biotechnology for Biofuels, 2018
Background Lytic polysaccharide monooxygenases (LPMO) release a spectrum of cleavage products from their polymeric substrates cellulose, hemicellulose, or chitin.
Erik Breslmayr, Marija Hanžek, Aoife Hanrahan, Christian Leitner, Roman Kittl, Božidar Šantek, Chris Oostenbrink, Roland Ludwig   +7 more
doaj   +1 more source

Lytic Polysaccharide Monooxygenases from Serpula lacrymans as Enzyme Cocktail Additive for Efficient Lignocellulose Degradation

Fermentation, 2023
Lytic polysaccharide monooxygenase (LPMO) could oxidize and cleavage the glycosidic bonds of polysaccharides in lignocellulose, thereby promoting the hydrolysis of polysaccharide substrates by glycoside hydrolases and significantly improving the ...
Fei Li, Yang Liu, Honglu Zhao, Xuan Liu, Hongbo Yu   +4 more
doaj   +1 more source

Reduced Processivity in a Chitobiohydrolase Enhances LPMO-Assisted Chitin Depolymerization. [PDF]

Biochemistry
Efficient enzymatic depolymerization of recalcitrant polysaccharides such as chitin and cellulose relies on processive glycoside hydrolases (GHs), whose efficiency can be enhanced through cooperation with lytic polysaccharide monooxygenases (LPMOs).
Votvik AK, Forsberg Z, Gautieri A, Eijsink VGH, Sørlie M.   +4 more
europepmc   +3 more sources

Current understanding of substrate specificity and regioselectivity of LPMOs [PDF]

Bioresources and Bioprocessing, 2020
AbstractRenewable biomass such as cellulose and chitin are the most abundant sustainable sources of energy and materials. However, due to the low degradation efficiency of these recalcitrant substrates by conventional hydrolases, these biomass resources cannot be utilized efficiently. In 2010, the discovery of lytic polysaccharide monooxygenases (LPMOs)
Xiaoli Zhou, Honghui Zhu
openaire   +2 more sources