LSD1/CoREST - H3-Histone Molecular Recognition: Inter-Domain Motions in an Allosteric Nanoscale Clamp Revealed by Computer Simulations [PDF]
Nadeem Ahmad Vellore, Riccardo Baron
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Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. [PDF]
Waterbury AL+11 more
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LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAF mutant colorectal cancer. [PDF]
Ladaika CA+5 more
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GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1 [PDF]
Roshana Thambyrajah+15 more
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Lysine Demethylase 1 Has Demethylase-Dependent and Non-Canonical Functions in Myofibroblast Activation in Systemic Sclerosis. [PDF]
Wasson CW+3 more
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Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation [PDF]
Taeko Wada+4 more
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Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity. [PDF]
Osumi T+5 more
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Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1
JuHyun Kim+4 more
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Discovery of highly potent and novel LSD1 inhibitors for the treatment of acute myeloid leukemia: structure-based virtual screening, molecular dynamics simulation, and biological evaluation. [PDF]
Hong Y+9 more
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