Results 21 to 30 of about 16,606 (224)

Outlook for tuberculosis elimination in California: An individual-based stochastic model. [PDF]

, 2019
RationaleAs part of the End TB Strategy, the World Health Organization calls for low-tuberculosis (TB) incidence settings to achieve pre-elimination (<10 cases per million) and elimination (<1 case per million) by 2035 and 2050, respectively. These
Barry, Pennan M, Cattamanchi, Adithya, Flood, Jennifer, Goodell, Alex J, Hill, Andrew, Kahn, James G, Marks, Suzanne M, McCabe, Devon, Porco, Travis C, Shete, Priya B, Vreman, Rick   +10 more
core   +3 more sources

Impact of latent tuberculosis infection on health and wellbeing: a systematic review and meta-analysis

European Respiratory Review, 2021
The impact of latent tuberculosis infection (LTBI) on health and wellbeing is not well understood. This review aims to evaluate the health and wellbeing of individuals with LTBI.
Yen Jun Wong, Noorliza Mohd Noordin, Salmaan Keshavjee, Shaun Wen Huey Lee   +3 more
doaj   +1 more source

The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition [PDF]

, 2016
M. tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding
Barry III, CE, Brandenburg, J, Prosser, G, Reiling, N, Wilkinson, KA, Wilkinson, RJ   +5 more
core   +1 more source

Prevalence of latent tuberculosis infection among participants of the national LTBI screening program in South Korea – A problem of low coverage rate with current LTBI strategy

Frontiers in Public Health, 2023
BackgroundThe Government of South Korea launched a national preemptive latent tuberculosis infection (LTBI) screening program in 2016, including more than 1. 6 million population in congregate settings. The objective of this study was to analyze LTBI prevalence and its risk factors in each setting.
Hyung Woo Kim, Jinsoo Min, Joon Young Choi, Ah Young Shin, Jun-Pyo Myong, Yunhee Lee, Hyeon Woo Yim, Hyunsuk Jeong, Sanghyuk Bae, Hoyong Choi, Hyekyung In, Ahyoung Park, Miri Jang, Hyeon-Kyoung Koo, Sung-Soon Lee, Jae Seuk Park, Ju Sang Kim   +16 more
openaire   +3 more sources

Elevated Circulating Concentrations of Interferon-Gamma in Latent Tuberculosis Infection

Pathogens and Immunity, 2016
Background: Latent tuberculosis infection (LTBI) has been associated with increased immune activation. We assessed circulating concentrations of interferon-gamma in persons with LTBI.
Moises Arturo Huaman, George S. Deepe, Jr., Carl J. Fichtenbaum   +2 more
doaj   +1 more source

Epidemiological impact of targeted interventions for people with diabetes mellitus on tuberculosis transmission in India: Modelling based predictions. [PDF]

, 2020
INTRODUCTION: Diabetes mellitus (DM) is a leading driver of tuberculosis (TB) disease in TB-DM burdened countries. We aimed to assess the impact on TB disease of several intervention strategies targeting people with DM in India.
Abu-Raddad, LJ, Awad, SF, Critchley, JA
core   +2 more sources

Latent tuberculosis infection is associated with increased unstimulated levels of interferon-gamma in Lima, Peru.

PLoS ONE, 2018
BackgroundWe previously reported increased unstimulated blood levels of interferon-gamma in persons with latent tuberculosis infection (LTBI) in the United States, suggesting enhanced immune activation in LTBI. To investigate this further in a TB-endemic
Moises A Huaman, David Henson, Paola L Rondan, Eduardo Ticona, Gustavo Miranda, Richard J Kryscio, Raquel Mugruza, Ernesto Aranda, Cesar Ticona, Susan Abarca, Paula Heredia, Andres Aguirre, Timothy R Sterling, Beth A Garvy, Carl J Fichtenbaum   +14 more
doaj   +1 more source

Gender disparities in latent tuberculosis infection in high-risk individuals: a cross-sectional study. [PDF]

PLoS ONE, 2014
Male predominance in active tuberculosis (TB) is widely-reported globally. Gender inequalities in socio-cultural status are frequently regarded as contributing factors for disparities in sex in active TB.
Wen-Ying Ting, Shiang-Fen Huang, Ming-Che Lee, Yung-Yang Lin, Yu-Chin Lee, Jia-Yih Feng, Wei-Juin Su   +6 more
doaj   +1 more source

Tricks to translating TB transcriptomics. [PDF]

, 2015
Transcriptomics and other high-throughput methods are increasingly applied to questions relating to tuberculosis (TB) pathogenesis. Whole blood transcriptomics has repeatedly been applied to define correlates of TB risk and has produced new insight into ...
Coussens, AK, Deffur, A, Wilkinson, RJ
core   +1 more source

Serum Biomarker Profile Including CCL1, CXCL10, VEGF, and Adenosine Deaminase Activity Distinguishes Active From Remotely Acquired Latent Tuberculosis

Frontiers in Immunology, 2021
IntroductionThere is an urgent medical need to differentiate active tuberculosis (ATB) from latent tuberculosis infection (LTBI) and prevent undertreatment and overtreatment.
Eveline M. Delemarre, Eveline M. Delemarre, Laura van Hoorn, Laura van Hoorn, Aik W. J. Bossink, Julia Drylewicz, Simone A. Joosten, Tom H. M. Ottenhoff, Onno W. Akkerman, Delia Goletti, Elisa Petruccioli, Assunta Navarra, Brigitte T. A. van den Broek, Sanne P. A. Paardekooper, Ineke van Haeften, Leo Koenderman, Leo Koenderman, Jan-Willem J. Lammers, Steven F. T. Thijsen, Regina W. Hofland, Regina W. Hofland, Stefan Nierkens, Stefan Nierkens   +22 more
doaj   +1 more source