Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla +12 more
core +4 more sources
Nurse‐led intervention to decrease drug use among LTBI positive homeless adults
AbstractBackgroundPeople experiencing homelessness (PEH) are disproportionately diagnosed with active tuberculosis. While promoting latent tuberculosis infection (LTBI) treatment has been a call to action, PEH engaging in substance use often experience challenges in completing LTBI treatment.MethodsIn this non‐randomized single arm study, we tested an ...
Adeline Nyamathi +10 more
openaire +4 more sources
Meira Erawati, Megah Andriany Department of Nursing, Faculty of Medicine, Universitas Diponegoro, Semarang, IndonesiaCorrespondence: Meira ErawatiDepartment of Nursing, Faculty of Medicine, Universitas Diponegoro, Jl. Prof.
Erawati M, Andriany M
doaj
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju +17 more
wiley +1 more source
Summary Background and Objectives Preventive tuberculosis (TB) therapy before initiating MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors for latent tuberculosis infection (LTBI) is supported by indirect evidence of TB reactivations with TNF inhibitors. However, direct evidence for MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors is limited.
Christoph Zeyen +4 more
wiley +1 more source
Factors associated with non-initiation of latent tuberculosis treatment among healthcare workers with a positive interferon-gamma releasing assay [PDF]
Despite widespread use of the interferon-gamma release assay for the diagnosis of latent tuberculosis infection (LTBI), the initiation rate of and factors associated with LTBI treatment among healthcare workers (HCWs) have not been studied in depth.
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core +4 more sources
Comparison of QFT-IT and QFT-Plus for Detecting Latent Tuberculosis in HIV-Infected Iranian Patients
Background: Tuberculosis (TB) is a major public health issue, especially among Human immunodeficiency virus (HIV)-infected individuals, where early detection of latent tuberculosis infection (LTBI) is crucial.
Zahra Abtahian +4 more
doaj +1 more source
Community-based cross-sectional survey of latent tuberculosis infection in Afar pastoralists, Ethiopia, using QuantiFERON-TB Gold In-Tube and tuberculin skin test [PDF]
Background There is little information concerning community-based prevalence of latent tuberculosis infection (LTBI) using T-cell based interferon-γ (IFN-γ) release assays (IGRAs), particularly in TB endemic settings.
Legesse, Mengistu +5 more
core +2 more sources
Tuberculosis-specific CD8 cells in HLA A*02-positive TB and LTBI patients [PDF]
Background: Understanding the CD8+ response against Mycobacterium tuberculosis (MTB) may be a key to improved TB diagnostics and vaccine development. Aims and Objectives: To detect a CD8+ T-cell response against Mycobacterium tuberculosis (MTB) in active tuberculosis (TB) and latent TB (LTBI), in HLA A*02 positive patients.
Fløe, Andreas +3 more
openaire +2 more sources
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source

