Results 51 to 60 of about 16,606 (224)

The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization. [PDF]

, 2015
Bacille Calmette-Guérin (BCG) immunization provides variable protection against tuberculosis. Prenatal antigen exposure may have lifelong effects on responses to related antigens and pathogens. We therefore hypothesized that maternal latent Mycobacterium
Akello, Mirriam, Cose, Stephen, Dockrell, Hazel M, Egesa, Moses, Elliott, Alison M, Kizindo, Robert, Lule, Swaib A, Mawa, Patrice A, Muwanga, Moses, Nkurunungi, Gyaviira, Smith, Steven G, Webb, Emily L   +11 more
core   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, Volume 13, Issue 17, 23 March 2026.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Cost-Effectiveness of LTBI Treatment for TB Contacts in British Columbia

Value in Health, 2008
Contacts of patients with active tuberculosis ("TB contacts") with a tuberculin skin test (TST) size > or = 5 mm are currently recommended treatment for latent TB infection (LTBI). Knowing the cost-effectiveness of LTBI therapy for specific TB contact subpopulations may improve the use of limited resources by reducing the treatment of persons at low TB
Tan, Michael C., Marra, Carlo A., Sadatsafavi, Mohsen, Marra, Fawziah, Morán-Mendoza, Onofre, Moadebi, Susanne, Elwood, R. Kevin, FitzGerald, J. Mark   +7 more
openaire   +2 more sources

Prevalence of Latent Mycobacterium Tuberculosis Infection (LTBI) in Saudi Arabia; Population based survey [PDF]

International Journal of Infectious Diseases, 2017
The annual risk of tuberculosis infection (ARTI) data in Saudi Arabia has not been updated since 1993.To estimate the prevalence of latent TB infection (LTBI) and ARTI in a population-based sample in Saudi Arabia using Tuberculin skin test (TST) and QuantiFERON TB Gold in tube (QFT-GIT) test.A population-based cross sectional study was conducted ...
Hanan H. Balkhy, Kamel El Beltagy, Aiman El-Saed, Badr Aljasir, Abdulhakeem Althaqafi, Adel F. Alothman, Mohammad Alshalaan, Hamdan Al-Jahdali   +7 more
openaire   +3 more sources

D‐Dimer: A Mediator of the Association Between Lymphocyte and Dissemination of Pulmonary Tuberculosis: A Retrospective Cohort Study

The Clinical Respiratory Journal, Volume 20, Issue 3, March 2026.
This study identifies D‐dimer as a key mediator between lymphocyte depletion and pulmonary tuberculosis dissemination. Our findings reveal that reduced lymphocyte counts increase dissemination risk partly by elevating D‐dimer levels, suggesting a critical link between immune deficiency and coagulopathy.
Yujun Lin, Di Wu, Xiaohong Chen, Lujing Jiang, Yiming Zeng   +4 more
wiley   +1 more source

Smoking Exposure and the Risk of Latent Tuberculosis Infection: Results from NHANES 2011–2012

Toxics
The association between smoking exposure and latent tuberculosis infection (LTBI) has been investigated in a few studies; however, further investigation is needed.
Xinsong Hu, Jiongya Liu, Yan Shao, Guoli Li, Honghuan Song, Qiao Liu, Cheng Chen, Limei Zhu   +7 more
doaj   +1 more source

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum [PDF]

, 2015
In an attempt to provide a reliable status of metal ions in children, new methods of analysis of children's sera are proposed. New flame atomic-absorption spectrometric (FAAS) methods are simple, cost- and time-effective and, above all, labor-, reagent ...
Bogden, Cernat, Ciftci, Dodig, Herlina, Ivka Zoričić Letoja, Lockitch, Luterotti, Luterotti, Luterotti, Meštrić, Moraes, Nenni, Pavić, Slavica Dodig, Svjetlana Luterotti, Tončica Vukman Kordić, Visser   +17 more
core   +4 more sources

Optimizing tuberculosis screening for immigrants in southern New Brunswick: A pilot study protocol.

PLoS ONE, 2022
IntroductionImmigrants from high tuberculosis-burdened countries have been shown to have an increased risk of latent tuberculosis infection (LTBI). To reduce the risk of increased tuberculosis cases in Canada, the country has a comprehensive immigration ...
Isdore Chola Shamputa, Duyen Thi Kim Nguyen, Doaa Higazy, Amani Abdelhadi, Hope MacKenzie, Michelle Reddin, Kimberley Barker, Duncan Webster   +7 more
doaj   +1 more source

Latent tuberculosis infection in myasthenia gravis patients on immunosuppressive therapy: high incidence yet moderate reactivation rate

Annals of Medicine, 2023
Background Immunosuppressive therapies (ISTs) are mainstays for management of myasthenia gravis (MG). Meanwhile, latent tuberculosis infection (LTBI) is common in the setting of high-burden countries. However, the prevalence of LTBI among MG patients and
Kangzhi Chen, Fei Jiang, Qian Zhou, Xiaohua Dong, Ting He, Yi Li, Zhaohui Luo, Weiwei Duan, Huan Yang   +8 more
doaj   +1 more source

Prevalence of Latent Tuberculosis Infection (LTBI) in Mexican Patients With Rheumatoid Arthritis (RA)

Cureus, 2023
Patients with rheumatoid arthritis (RA) are at increased risk of developing tuberculosis, and even more so if they receive biological agents. In Mexico, the prevalence of latent tuberculosis infection (LTBI) in RA diagnosed by interferon-gamma release assay (IGRA) is largely unknown.
Zavala del Ángel, Abel Eduardo, Morales-Romero, Jaime, Zenteno-Cuevas, Roberto, Enciso Moreno, José Antonio, Mata Miranda, María del Pilar, Martínez Zapata, Jorge Luis, Sampieri Ramírez, Clara Luz, Nachón García, María Gabriela, Blázquez Morales, María Sobeida Leticia, Álvarez-Bañuelos, María Teresa, Cruz López, José Artemio, Demeneghi-Marini, Verónica Patricia, González-López, Laura, Gámez-Nava, Jorge Iván   +13 more
openaire   +2 more sources