Results 61 to 70 of about 8,462 (183)

Leveraging Social Risk Factor Screening Infrastructure in Rheumatology Clinics to Respond to Rising Rates of Tuberculosis Among Individuals Experiencing Homelessness

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective Immunocompromised individuals with rheumatic conditions have heightened risk of tuberculosis (TB) infection, reactivation, and severe disease. Patients with social risks are especially vulnerable. After an alert of increased TB rates among individuals experiencing homelessness in Massachusetts, we leveraged the existing social risk screening ...
Rebecca Summit, Dylan B. Tierney, Taussia Boadi, Tyler Green, Karli Retzel, Virginia Bills, Nancy A. Shadick, Leah Santacroce, Sara R. Schoenfeld, Candace H. Feldman   +9 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda

Frontiers in Immunology
BackgroundEfforts to eradicate tuberculosis (TB) are threatened by diabetes mellitus (DM), which confers a 3-fold increase in the risk of TB disease.
Phillip Ssekamatte, Phillip Ssekamatte, Rose Nabatanzi, Diana Sitenda, Marjorie Nakibuule, Bernard Ssentalo Bagaya, Davis Kibirige, Andrew Peter Kyazze, David Patrick Kateete, Obondo James Sande, Reinout van Crevel, Stephen Cose, Irene Andia Biraro, Irene Andia Biraro   +13 more
doaj   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, Volume 13, Issue 17, 23 March 2026.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Higher blood manganese level associated with increased risk of adult latent tuberculosis infection in the US population

Frontiers in Public Health
BackgroundThe associations between blood heavy metal levels and latent tuberculosis infection (LTBI) have not been fully elucidated. The aim of this study was to investigate the potential association between blood heavy metal levels and LTBI in adults ...
Min Qi, Min Qi, Huan Zhang, Huan Zhang, Jian-Qing He, Jian-Qing He   +5 more
doaj   +1 more source

Implementation of latent tuberculosis infection screening and treatment among newly arriving immigrants in the Netherlands: A mixed methods pilot evaluation.

PLoS ONE, 2019
IntroductionTo reach pre-elimination levels of tuberculosis (TB) incidence in the Netherlands, prevention of TB among immigrants through diagnosis and treatment of latent TB infection (LTBI) is needed.
Ineke Spruijt, Connie Erkens, Jeanine Suurmond, Erik Huisman, Marga Koenders, Peter Kouw, Sophie Toumanian, Frank Cobelens, Susan van den Hof   +8 more
doaj   +1 more source

Latent tuberculosis infection and infection-associated risk factors for miner workers with silicosis in eastern China

BMC Pulmonary Medicine
Objectives Silicosis people are at high risk of developing pulmonary tuberculosis. Whether silica exposure increases the likelihood of latent tuberculosis infection (LTBI) was not well understood, and potential factors involved in LTBI risk among ...
Xinsong Hu, Cheng Chen, Qianqian Gao, Lang Zhou, Yan Shao, Guoli Li, Honghuan Song, Qiao Liu, Lei Han, Limei Zhu   +9 more
doaj   +1 more source

Latent tuberculosis infection and diagnostic performance of the tuberculin skin test among type 2 diabetics in Sana’a city, Yemen

BMC Infectious Diseases
Background Tuberculosis (TB) is one of the most widespread infectious diseases worldwide, typically persisting in the body as a latent TB infection (LTBI). Patients with type 2 diabetes have an increased risk of LTBI progressing to active TB.
Rashad Abdul-Ghani, Asmaa Al-Awadi, Nuha Al-aghbari, Abdullah A. Al-Mikhlafy, Sadeq S. Abdulmoghni, Sami S. Al-dobai, Nedal F. Nauman   +6 more
doaj   +1 more source

Intestinal Helminth Infections and Their Association with QuantiFERON-TB Gold Plus Test Performance in an Endemic Setting, Northwest Ethiopia

Infection and Drug Resistance
Yohannes Zenebe,1– 3 Markos Abebe,3 Abaineh Munshea,2,4 Gizachew Yismaw,5 Meaza Zewde,3 Mekdelawit Alemayehu,3 Roland Lang,6 Meseret Habtamu3 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir ...
Zenebe Y, Abebe M, Munshea A, Yismaw G, Zewde M, Alemayehu M, Lang R, Habtamu M   +7 more
doaj  

Latent tuberculosis infection (LTBI): a real host defence or a permanent threat? [PDF]

Le infezioni in medicina, 2016
Screening of latent infection by Mycobacterium tuberculosis (LTBI) and treatment of positive subjects is the key point in the prevention of TB; such a strategy should be performed mainly among individuals with risk of progression. Progression from LTBI to active TB is highest both in recent contacts of patients with active TB, and in immunocompromised ...
SANDUZZI ZAMPARELLI, ALESSANDRO, PONTICIELLO, ANTONIO, BOCCHINO, MARIALUISA, PERNA, FRANCESCO, Vatrella, Alessandro   +4 more
openaire   +2 more sources