Interferon-gamma release assays in tuberculous uveitis: a comprehensive review [PDF]
International Journal of Ophthalmology, 2022 Tuberculous uveitis (TBU) comprises a broad clinical spectrum of ocular manifestations, making its diagnosis challenging. Ophthalmologists usually require evidence from investigations to confirm or support a clinical diagnosis of TBU.
Usanee Tungsattayathitthan +4 more
doaj +4 more sources
Diagnostic Value of Interferon-Gamma Release Assays for Tuberculosis in the Immunocompromised Population [PDF]
Diagnostics, 2022 Interferon-gamma release assays (IGRAs) are widely used in the diagnosis of Mycobacterium tuberculosis (M. tuberculosis) infection by detecting interferon-γ released by previously sensitized T-cells in-vitro.
Ying Yang, Chun-Zhen Hua
exaly +4 more sources
Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people [PDF]
International Journal of Infectious Diseases, 2021 SUMMARY: Background: Interferon gamma release assays (IGRAs) are used to detect latent Mycobacterium tuberculosis (M.tb) infection (LTBI) in adults, but their performance in older people is not well-established.
Julia Scordo +2 more
exaly +4 more sources
Interferon gamma release assays for diagnosis of osteoarticular tuberculosis: A systematic review and meta-analysis. [PDF]
PLoS ONE, 2022 BackgroundAlthough the Interferon Gamma Release Assays (IGRA) is often used to identify latent tuberculosis, it also plays a crucial role in diagnosing active extrapulmonary tuberculosis.
Chunnian Ren, Jie Tang, Liangfeng Xia
doaj +2 more sources
The Role of Interferon-Gamma Release Assays in Diagnosis of Latent Tuberculosis Infection in Children [PDF]
Acta Clinica Croatica, 2023 Despite numerous published papers, diagnosis of latent tuberculosis infection (LTBI) in children is still an undefined area. The importance of this topic lies in the fact that one third of the world’s population is infected with Mycobacterium (M ...
Mateja Šegović +2 more
doaj +2 more sources
Performance of two interferon-gamma release assays for tuberculosis infection screening in Kawasaki children before immunosuppressive therapy [PDF]
Frontiers in Pediatrics, 2023 ObjectiveWe aimed to compare QuantiFERON-TB Gold In-Tube (QFT-GIT) and X.DOT-TB for screening latent tuberculosis infection (LTBI) in kawasaki patients, and to identify the risk factors associated with indeterminate IGRA results.MethodsWe conducted a ...
Hao Chen +9 more
doaj +2 more sources
Diagnostic utility of quantitative interferon-gamma release assays in elderly patients with tuberculosis [PDF]
Microbiology SpectrumEvidence regarding the diagnostic value of quantitative interferon-gamma release assay (IGRA) results in elderly populations is limited, and large-scale data for QuantiFERON-TB Gold Plus (QFT-Plus) are scarce. We evaluated QFT-Plus and T-SPOT.TB (T-SPOT)
Yoshikazu Mutoh +14 more
doaj +2 more sources
In-hospital blood collection increases the rate of indeterminate results in interferon-gamma release assays [PDF]
Therapeutic Advances in Respiratory Disease, 2022 Background: The interferon (IFN)-γ release assay (IGRA) has recently been established as a method to evaluate the infection status of tuberculosis instead of the tuberculin skin test. However, indeterminate results can create challenges to interpretation.
Yuki Osakabe +14 more
doaj +2 more sources
Prevalence of indeterminate tuberculosis interferon‐gamma release assays in COVID‐19 patients: Systematic review and meta‐analysis [PDF]
Health Science Reports, 2023 Background and Aims The reliability of interferon‐gamma‐release‐assays (IGRAs) for tuberculosis (TB) testing in coronavirus disease 2019 (COVID‐19) patients is unknown.
Aicha Ben Tekaya +6 more
doaj +2 more sources
Diagnostic Accuracy of Interferon-Gamma Release Assays for Tuberculous Meningitis: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundIn this study, we evaluated and compared the accuracy of blood and cerebrospinal fluid (CSF) interferon release tests [interferon-gamma release assays (IGRAs)] in the diagnosis of tuberculous meningitis (TBM) by a meta-analysis of the relevant ...
An Wen +12 more
doaj +2 more sources