Results 31 to 40 of about 8,462 (183)

Co‐Occurring Risk Factors for Tuberculosis Preventive Treatment Non‐Adherence Among People Living With HIV in Ethiopia: A Latent Class Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective Non‐adherence to tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) is a critical issue in Ethiopia and other Sub‐Saharan African countries, where both TB and HIV burdens are high. To reduce TPT non‐adherence among PLHIV, it is crucial to identify those at risk and implement targeted interventions. Therefore,
Edao Sinba Etu, Jet Fransen, Biftu Geda, Kemal Ahmed Kuti, Anteneh Fikrie, Mark Spigt   +5 more
wiley   +1 more source

Latent TB Infection (LTBI) – Mycobacterium tuberculosis pathogenesis and the dynamics of the granuloma battleground [PDF]

International Journal of Infectious Diseases, 2019
Latent tuberculosis infection (LTBI) is established in over 90% of persons infected with Mycobacterium tuberculosis (Mtb), from whom new active TB cases will arise. Understanding the spatio-temporal dynamics of host immune responses in LTBI granulomas is essential to designing effective post-exposure therapies that inhibit progression to TB ...
Martin Rao, Giuseppe Ippolito, Sayoki Mfinanga, Francine Ntoumi, Dorothy Yeboah-Manu, Cristina Vilaplana, Alimuddin Zumla, Markus Maeurer   +7 more
openaire   +7 more sources

Management of childhood and adolescent latent tuberculous infection (LTBI) in Germany, Austria and Switzerland

PLOS ONE, 2021
Background Majority of active tuberculosis (TB) cases in children in low-incidence countries are due to rapid progression of infection (latent TB infection (LTBI)) to disease. We aimed to assess common practice for managing paediatric LTBI in Austria, Germany and Switzerland prior to the publication of the first joint national guideline for paediatric
Ulrich von Both, Philipp Gerlach, Nicole Ritz, Matthias Bogyi, Folke Brinkmann, Stephanie Thee   +5 more
openaire   +5 more sources

Comparison of QFT-IT and QFT-Plus for Detecting Latent Tuberculosis in HIV-Infected Iranian Patients

Novelty in Biomedicine
Background: Tuberculosis (TB) is a major public health issue, especially among Human immunodeficiency virus (HIV)-infected individuals, where early detection of latent tuberculosis infection (LTBI) is crucial.
Zahra Abtahian, Elaheh Eghbal, Payam Tabarsi, Farima Khalili, Mohammad Javad Nasiri   +4 more
doaj   +1 more source

Upregulation of CREB1 by Mycobacterium Tuberculosis Transcriptionally Activates TREM2 to Promote Macrophage M2 Polarization

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Tuberculosis, caused by Mycobacterium tuberculosis (MTB), affects approximately 25% of people globally as latent infection (LTBI). Although macrophage CREB activation promotes MTB survival, the underlying mechanisms remain unclear. This study reveals, for the first time, how MTB modulates M2 macrophage polarization through the CREB1/TREM2 ...
Yufeng Zhu, Mingzhong Xu, Danxia Liu, Wei Ning, Miaomiao Wang, Feifan Huang, Zhen An, Jingsong Qiu, Xian Tang, Peipei Wang, Bin Tian, Lan Wen   +11 more
wiley   +1 more source

P165 Latent tuberculosis infections (ltbi) national screening programme [PDF]

Early detection and screening in TB, 2017
Background The new entrant TB screening programme identified very few persons for Latent TB screening locally. However, following national funding for community LTBI screening, 12 GP practices were identified to undertake IGRA testing in “high risk” registered persons.
YO Abunga, M Day, N Wright, SO Brij
openaire   +1 more source

Mycobacterium tuberculosis and SARS‐CoV‐2 Co‐Infection: An Efficient Cell Model to Study Lung Host–Pathogen Interactions

Current Protocols, Volume 6, Issue 8, August 2026.
Abstract In less than a year, SARS‐CoV‐2 managed to displace Mycobacterium tuberculosis (Mtb) as the leading cause of death worldwide due to a single infectious agent. Both pathogens affect the respiratory tract, mainly the lungs. However, the impact that a possible Mtb + SARS‐CoV‐2 co‐infection can have on the host response is still unknown. Herein we
Thays Maria Costa de Lucena, Débora Elienai de Oliveira Miranda, Juliana Vieira de Barros Arcoverde, Mariana Souza Bezerra Cavalcanti, Willyene Marilia Dantas, Lindomar José Pena, Michelle Christiane da Silva Rabello, Jaqueline de Azevêdo Silva   +7 more
wiley   +1 more source

Health Screening and Post‐Arrival Services for Refugee Children From Afghanistan

Journal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1403-1410, August 2026.
ABSTRACT Aim To examine refugee health screening and services for Afghan children in the unique context of emergency expedited humanitarian resettlement in Melbourne, Australia. Methods Retrospective audit of Afghan children who attended a specialist child refugee health service between August 2021–April 2024. Results Participants included 218 children
Amy Williamson, Eva Sudbury, Rija Khanal, Jade Woon, Jennifer Schaefer, Georgia Paxton   +5 more
wiley   +1 more source

Smoking Exposure and the Risk of Latent Tuberculosis Infection: Results from NHANES 2011–2012

Toxics
The association between smoking exposure and latent tuberculosis infection (LTBI) has been investigated in a few studies; however, further investigation is needed.
Xinsong Hu, Jiongya Liu, Yan Shao, Guoli Li, Honghuan Song, Qiao Liu, Cheng Chen, Limei Zhu   +7 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source