Results 31 to 40 of about 14,132 (212)

Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI

Journal of Clinical Medicine, 2019
Weekly rifapentine and isoniazid therapy (known as 3HP) for latent tuberculosis infection (LTBI) is increasingly used, but systemic drug reactions (SDR) remain a major concern.
Meng-Rui Lee, Hung-Ling Huang, Shu-Wen Lin, Meng-Hsuan Cheng, Ya-Ting Lin, So-Yi Chang, Bo-Shiun Yan, Ching-Hua Kuo, Po-Liang Lu, Jann-Yuan Wang, I. Chong   +10 more
semanticscholar   +1 more source

Acceptability of levofloxacin dispersible and non-dispersible tablet formulations in children receiving TB preventive treatment

IJTLD Open
BACKGROUND: We evaluated the palatability and acceptability of a 100 mg dispersible and a non-dispersible 250 mg levofloxacin (LVX) tablet formulation in children.
D. T. Wademan, H. R. Draper, S. E. Purchase, M. Palmer, A. C. Hesseling, L. Van der Laan, A. J. Garcia-Prats   +6 more
doaj   +1 more source

A retrospective analysis of the effect of latent tuberculosis infection on clinical pregnancy outcomes of in vitro fertilization–fresh embryo transferred in infertile women

Open Medicine, 2023
In areas with high incidence of tuberculosis (TB), there are more infertile women who underwent in vitro fertilization (IVF) and have latent TB infection (LTBI), and thus, their potential risks should be paid enough attention.
Jia Xinzhuan, Wei Lan, Zhang Na, Zheng Bolin, Li Mengya, Wang Hongxia, Liu Erhuan, Xu Jie, Sun Guangyu, Zhang Zhengmao   +9 more
doaj   +1 more source

The Dynamic Change of Immune Checkpoints and CD14+ Monocytes in Latent Tuberculosis Infection

Biomedicines, 2021
Controlling latent tuberculosis infection (LTBI) is important for preventing tuberculosis (TB). However, the immune regulation of LTBI remains uncertain. Immune checkpoints and CD14+ monocytes are pivotal for immune defense but have been scarcely studied
Ping-Huai Wang, Ming-Fang Wu, Chi-Yu Hsu, Shu-Yung Lin, Ya-Nan Chang, Ho-Shen Lee, Yu-Feng Wei, Chin-Chung Shu   +7 more
doaj   +1 more source

Performance evaluation of the LIOFeron®TB/LTBI IGRA for screening of paediatric LTBI and tuberculosis

European Journal of Pediatrics
Abstract Purpose: High-accuracy diagnostic screening tests for Mycobacterium tuberculosis (MTB) infection are required, primarily to detect patients with latent infections (LTBIs) in order to avoid their progression to active tuberculosis disease. The performance of the novel IGRA LIOFeron®TB/LTBI was evaluated in children. The originality of
Chiara Della Bella, Marco Antonio Motisi, Elisabetta Venturini, Sofia D’Elios, Evangelia Asvestopoulou, Agnese Maria Tamborino, Luisa Galli, Mario Milco D’Elios, Elena Chiappini   +8 more
openaire   +3 more sources

Engaging with civil society to improve access to LTBI screening for new migrants in England: a qualitative study.

The International Journal of Tuberculosis and Lung Disease, 2019
SETTING The latent tuberculous infection (LTBI) programme in England, UK, offers testing and treatment to new migrants from high tuberculosis incidence countries. However, the rates of LTBI testing, treatment acceptance and completion are suboptimal and
L. Berrocal-Almanza, J. Botticello, H. Piotrowski, N. Karnani, O. Kon, A. Lalvani, D. Zenner   +6 more
semanticscholar   +1 more source

Screening for tuberculosis and LTBI in diabetes patients, Pohnpei, Federated States of Micronesia [PDF]

Public Health Action, 2014
A retrospective cohort study was performed in Pohnpei, a small Pacific Island, to evaluate the feasibility and results of screening adult diabetes (DM) patients for tuberculosis (TB) and latent tuberculous infection (LTBI) using a symptom screen, tuberculin skin testing and chest radiography. Of 79 patients, 65 (82%) completed screening.
R R, Defang, R, Brostrom, S, Ram, E, Johnson, P S, Perman   +4 more
openaire   +2 more sources

Children and providers’ perspectives on once-weekly rifapentine and isoniazid TB preventive therapy

IJTLD Open
BACKGROUND: TB preventive treatment (TPT) prevents the development of TB disease in individuals at risk of progression from infection to disease. However, implementation of TPT for children is poor in most high-burden settings. The long duration and pill
A.J. Marthinus, D.T. Wademan, Z. Saule, Y. Hirsch-Moverman, L. Viljoen, J. Winckler, L. van der Laan, M. Palmer, S.L. Barnabas, R. Boyd, A.C. Hesseling, G. Hoddinott   +11 more
doaj   +1 more source

Differed IL-1 Beta Response between Active TB and LTBI Cases by Ex Vivo Stimulation of Human Monocyte-Derived Macrophage with TB-Specific Antigen

Disease Markers, 2019
Background The difference of macrophage-specific interleukin-1 beta (IL-1b) response between latent tuberculosis infection (LTBI) and active tuberculosis (TB) remains less studied.
Meng-Rui Lee, Lih-Yu Chang, Chia-Hao Chang, Bo-Shiun Yan, Jann-Yuan Wang, Wan-Hsin Lin   +5 more
semanticscholar   +1 more source

Prevalence of Latent Mycobacterium Tuberculosis Infection (LTBI) in Saudi Arabia; Population based survey.

International Journal of Infectious Diseases, 2017
BACKGROUND The annual risk of tuberculosis infection (ARTI) data in Saudi Arabia has not been updated since 1993. OBJECTIVES To estimate the prevalence of latent TB infection (LTBI) and ARTI in a population-based sample in Saudi Arabia using Tuberculin
H. Balkhy, K. E. El Beltagy, A. El-Saed, B. Aljasir, A. Althaqafi, A. Alothman, Mohammad Alshalaan, H. Al-Jahdali   +7 more
semanticscholar   +1 more source