Results 131 to 140 of about 65,198 (258)
Impairment of mossy fiber-CA3 LTP by a sialidase inhibitor.
(A) LTP was induced at 30 min by tetanic stimulation in the presence of 50 μM AP5. DANA (300 μM), 1 μM DCG-IV and 10 μM CNQX were applied at 10–70, 70–80 and 80–90 min, respectively. n = 7 each. The inset shows representative fEPSPs recorded at the times
Shou Mamada (3270204) +8 more
core +1 more source
Degradation Mechanism of Phosphate‐Based Li‐NASICON Conductors in Alkaline Environment
The presence of water in the cathode of a Li‐air battery shifts reactions to produce LiOH, creating a corrosive, alkaline environment. This study investigates the alkaline stability of the common Li‐NASICON solid‐state conductor chemistries through a systematic experimental study combined with computational modeling to understand the degradation ...
Benjamin X. Lam +3 more
wiley +1 more source
Exploiting Ferroelectric and Spintronic Dynamics for Neural Network Computation
Ferroelectric and spintronic devices, relying on the control of polarization and magnetization, offer intrinsically fast, durable, energy‐efficient, and low‐latency building blocks for analog in‐memory computing. The hysteretic dynamics of an order parameter are leveraged to provide nonvolatile, multistate memory and nonlinear switching. Brain‐inspired
Dashiell Harrison +4 more
wiley +1 more source
AP2 (APETALA2)/EREBP (ethylene-responsive element-binding protein), cytochrome c oxidase (COX) and nonspecific lipid transfer proteins (LTP) play important roles in the response to drought stress.
Amaal Maghraby, Mohamed Alzalaty
doaj +1 more source
Energy‐Aware Perturbation Optimization for Memristor‐Array Convolutional Neural Networks
Memristor‐array inference becomes more energy efficient when layer inputs are reshaped before computation. Sinusoidal perturbation encoding with dual‐threshold screening reduces active voltage pulses and contracts ADC input‐current ranges, jointly lowering crossbar and peripheral energy while preserving accuracy across hardware MNIST validation, deep ...
Ao Xu +6 more
wiley +1 more source
A two‐terminal IGZO memtransistor enabling low‐voltage operation is demonstrated through coupling enhancement. By utilizing drain‐induced Fowler–Nordheim tunneling, the device achieves programming below 10 V with a large memory window and high on/off ratio.
Junhyeong Park +5 more
wiley +1 more source
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li +3 more
wiley +1 more source
MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
KIF1A‐Mediated Axonal Transport of Netrin‐1 in iPSC‐Derived Human Forebrain Neurons
ABSTRACT Netrin‐1 is a secreted laminin‐like protein that functions as a guidance cue for axon pathfinding in development. Netrin‐1 also modulates synapse formation in developing neurons and long‐term potentiation in mature neurons. Netrin‐1 is expressed in human neurons; however, its intracellular distribution and trafficking have not been assessed ...
T. Y. Leung +5 more
wiley +1 more source

