Results 121 to 130 of about 60,315 (306)

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Nitric oxide signaling exerts bidirectional effects on plasticity inductions in amygdala.

PLoS ONE, 2013
It has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nucleus of the amygdala (LA) constitutes an essential cellular mechanism contributing to encoding of conditioned fear.
Ryong-Moon Shin, Makoto Higuchi, Tetsuya Suhara   +2 more
doaj   +1 more source

MINO prevents LTP impairment during sepsis

, 2017
Sepsis-associated encephalopathy is a major complication during sepsis, and an effective treatment remains unknown. Although minocycline (MINO) has neuroprotective effects and is an attractive candidate for treating sepsis-associated encephalopathy, the ...
Hoshino, Koji, Mineji Hayakawa, Koji Hoshino, Yuji Morimoto, Morimoto, Yuji, Hayakawa, Mineji   +5 more
core   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

, 2008
Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of the human chromosome 21 (Hsa21). Recently, O’Doherty and colleagues in an earlier study generated a new genetic mouse model of DS (Tc1) that carries an almost complete ...
Morice, E., Cooke, S.F., Bliss, T.V.P., Vanes, L., Andreae, L.C., Tybulewicz, V.L.J., Fisher, E.M.C.   +6 more
core  

Evidence for constitutive protein synthesis in hippocampal LTP stabilization

, 2013
The notion that blockade of constitutive protein synthesis underlies the effect of protein synthesis inhibitors (PSIs) on long-term potentiation (LTP) stabilization was examined using the rat hippocampal CA3-CA1 synapse.
Abbas, Abdul-Karim,
core   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Tubulin expression in LTP-stimulated rats.

, 2014
(a) LTP of fEPSPs in the medial perforant path synapses (MML) and heterosynaptic LTD in the lateral perforant path synapses (OML), n = 8. (b) Representative Western blot showing tubulin expression in laser microdissected tissue from one LTP-stimulated ...
Wickliffe C. Abraham (153143), Joanna M. Williams (153149), Jeremy T. T. Kennard (542293), Diane Guévremont (542294), Sara E. Mason-Parker (542295)   +4 more
core   +1 more source

Electromagnetic Radiation Stimulated Learning in Perovskite Nickelates

Advanced Science, EarlyView.
ABSTRACT Biological plasticity refers to the ability of synapses to strengthen or weaken over time. These adaptive properties play a fundamental role in learning and memory, spanning many orders of magnitude in timescales. Short‐term plasticity (STP) arises from rapid correlative activity, while long‐term plasticity (LTP) is governed by slower ...
Ranjan Kumar Patel, Kabir Zama, Matthew Smart, Ramya Eathirajan, Ivan Seskar, Narayan Mandayam, Guangxin Ni, Martin Mönnigmann, Shriram Ramanathan   +8 more
wiley   +1 more source

AMPK activation inhibits L-LTP expression.

, 2013
A) AMPK activation inhibits LTP induced by HFS. 10 mM 2DG (n = 10) reduces L-LTP to 10% of control (n = 20) (p = 0.034). 5 µM metformin (n = 8) reduces L-LTP to 40% of control (p = 0.028). B) AMPK activation inhibits LTP induced by TBS. 10 mM 2DG reduces
Kenneth J. O'Riordan (199412), Matthew Wagoner (367466), Susan M. K. Osting (367465), Corinna Burger (199443), Avtar Roopra (140005), Wyatt B. Potter (367463), David Barnett (367464)   +6 more
core   +1 more source