Results 71 to 80 of about 60,315 (306)
What does LTP tell us about the roles of CaMKII and PKMζ in memory?
Molecular Brain, 2018 In “Criteria for identifying the molecular basis of the engram (CaMKII, PKMζ),” Lisman proposes that elucidating the mechanism of LTP maintenance is key to understanding memory storage.
Todd Charlton Sacktor +1 more
doaj +1 more source
Post-LTP does not occlude the induction of pre-LTP.
, 2013 A, Post-LTP protocol, delivered to thalamic input, resulted in potentiation of EPSP to 144 ± 13% of baseline amplitude at thirty minutes after the induction (n=5, paired t test ...
Makoto Higuchi (217616) +2 more
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission
Frontiers in Pharmacology, 2017 Cannabinoid receptor 1 (CB1R) is widely distributed in the central nervous system, in excitatory and inhibitory neurons, and in astrocytes. CB1R agonists impair cognition and prevent long-term potentiation (LTP) of synaptic transmission, but the ...
Armando Silva-Cruz +6 more
doaj +1 more source
Advanced Science, EarlyView.An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang +7 more
wiley +1 more source
PLoS ONE, 2012 Current thinking about LTP triggered in the area CA1 of hippocampal slices is ruled by two "dogmas": (1) A single train of high-frequency stimulation is sufficient to trigger short-lasting LTP (1-3 h), whereas multiple trains are required to induce long ...
Agnès Villers +2 more
doaj +1 more source
A Congestion Control Approach for Licklider Transmission Protocol
IEEE Access, 2019 Delay Tolerant Networks (DTN) are designed to deal with the long delay of space network and frequent link interruption, in 2002. Licklider Transmission Protocol (LTP) was designed to replace the Internetworking Protocol (IP) and Transmission Control ...
Yongjing Ni, Guoyan Huang
doaj +1 more source
Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model. [PDF]
PLoS Computational Biology, 2012 Protein synthesis-dependent, late long-term potentiation (LTP) and depression (LTD) at glutamatergic hippocampal synapses are well characterized examples of long-term synaptic plasticity.
Paul Smolen +2 more
doaj +1 more source
Effect of 5-HT4 receptors on LTP.
, 2014 A1: HFS induces LTP under control conditions. A2: The 5-HT4 receptor agonist RS 67333 does not alter LTP. A3: The 5-HT4 receptor antagonists RS 39604 does not modulate LTP. B1: stHFS induces PTP but not LTP under control conditions.
Pawel Fidzinski (406066) +4 more
core +1 more source
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source