Results 241 to 250 of about 325,683 (268)

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

ATP modulates holdase activity of fungal and human 110-kilodalton heat shock proteins to promote protein folding. [PDF]

Protein Sci
Kidd JM, Sun C, Garay A, Keplinger M, Richter C, May AE, Liu Q.   +6 more
europepmc   +1 more source

Coronavirus M Protein Hijacks Toll-Interacting Protein (TOLLIP) to Suppress NF-κB Signaling and Promote Immune Evasion. [PDF]

MedComm (2020)
Zhang Y, Kang L, Zhong Y, Shao S, Xue S, Liu C, Zheng X, Lin JW, Chen Y, Luo F, Wan H.   +10 more
europepmc   +1 more source

Association of the FTO gene polymorphism with the features of the clinical course of tuberculosis infection. [PDF]

BMC Infect Dis
Zhang J, Wang MJ, Jiang F, He JQ.
europepmc   +1 more source

mRNA Delivery by Lipoamino Fatty Acid-Peptide Polyplexes in Different Lung Cell Models and Lungs. [PDF]

Polymers (Basel)
Thalmayr S, Müller J, Polewka V, Gialdini I, Nguyen A, Dohmen C, Lamb DC, Merkel OM, Wagner E.   +8 more
europepmc   +1 more source

Mutational analyses of an instability domain reveal its conserved role in the regulation of class-B ARF levels in <i>Arabidopsis</i>. [PDF]

Proc Natl Acad Sci U S A
Ban Z, Prigge MJ, Zhu Y, Morffy N, Neher WR, Muroyama A, Strader L, Estelle M.   +7 more
europepmc   +1 more source

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Beyond luciferase-luciferin system: Modification, improved imaging and biomedical application

Coordination Chemistry Reviews, 2023
Xiaorui Shi, Chu Tang, Fu Wang
exaly  

Supramolecular Control over Split‐Luciferase Complementation

Angewandte Chemie - International Edition, 2016
Lech-Gustav Milroy, Tom F A De Greef, Maarten Merkx   +2 more
exaly