Results 251 to 260 of about 417,647 (313)

A single-nucleotide enhancer mutation overrides chromosomal sex to drive XX male development. [PDF]

Nat Commun
Abberbock E, Ridnik M, Stévant I, Weiss R, Bamberger C, Ziv Lhermann S, Lubman M, Yao YM, Afek A, Poulat F, Gonen N.   +10 more
europepmc   +1 more source

Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission. [PDF]

J Virol
Kuryshko M, Luttermann C, Bayoumi M, Mostafa A, Weißmann J, Schäfer A, Wendt L, Hoenen T, Müller J, Martinez-Sobrido L, Mettenleiter TC, Abdelwhab EM.   +11 more
europepmc   +1 more source

The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate recruitment. [PDF]

PLoS Pathog
Vandewinkel B, Torrekens S, Claes Z, Bollen M, Henckaerts E.   +4 more
europepmc   +1 more source

Repurposing nuclear receptors for ligand-responsive liquid condensate formation and gene regulation. [PDF]

Nat Commun
Rihtar E, Fink T, Ivanovski F, Koplan E, Jerala R.   +4 more
europepmc   +1 more source

ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors.

Chem
Kahler JP, Ellenbroek BD, van der Noord VE, van de Water B, Pomplun SJ.   +4 more
europepmc   +1 more source

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Crystalline firefly luciferase

Biochimica et Biophysica Acta, 1956
Abstract 1. 1. The method for purification and crystallization of firefly luciferase is described. 2. 2. The crystalline enzyme is apparently homogenous as evidenced by ultracentrifugation a and electrophoretic determinations. The molecular weight is probably around 100,000 and the isoelectric point between pH 6.2 and 6.3. 3. 3.
A A, GREEN, W D, MCELROY
openaire   +2 more sources

Bioluminescence assays: multicolor luciferase assay, secreted luciferase assay and imaging luciferase assay

Expert Opinion on Drug Discovery, 2010
By selecting the most appropriate bioluminescence assay, the researcher can study the underlying molecular mechanisms of a physiological system and the effects of a drug throughout the body.This review covers three luciferase assay systems: the multicolor luciferase assay, secreted luciferase assay and imaging luciferase assay. These assays are applied
Yoshihiro, Nakajima, Yoshihiro, Ohmiya
openaire   +2 more sources

Firefly luciferase inhibition

Journal of Photochemistry and Photobiology B: Biology, 2010
Firefly luciferase (Luc) is the most studied of the luciferase enzymes and the mechanism and kinetics of the reactions catalyzed by this enzyme have been relatively well characterized. Luc catalyzes the bioluminescent reaction involving firefly luciferin (D-LH(2)), adenosine triphosphate (ATP), magnesium ion and molecular oxygen with the formation of ...
João M. M. Leitão, Joaquim C. G. Esteves da Silva   +1 more
openaire   +3 more sources