By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Correction to "Homosalate Boosts the Release of Tumour-derived Extracellular Vesicles With Protection Against Anchorage-Loss Property". [PDF]
europepmc +1 more source
The bHLH transcription factor PIL1 orchestrates starch synthesis in key cereal crops. [PDF]
Meng Y +9 more
europepmc +1 more source
The rs713586 risk variant dysregulates ADCY3 rather than DNAJC27, leading to obesity through ZFP42-TET1-mediated DNA methylation. [PDF]
Wang W +8 more
europepmc +1 more source
Evaluation of the Ligand-Independent Activation of a VHH-Based Anti-CD19 SynNotch Receptor by Dual-Luciferase Assay. [PDF]
Asaadi Y, Rahbarizadeh F.
europepmc +1 more source
A broadly applicable split-luciferase biosensor approach for rapid antibody detection in emerging infectious diseases. [PDF]
Li X +9 more
europepmc +1 more source
Poly(A) variants supporting robust transmission stability in bacteria and high protein expression in animals for mRNA <i>in vitro</i> transcription. [PDF]
Chen H +12 more
europepmc +1 more source

