Results 61 to 70 of about 271,314 (298)

Chemical Biology Strategies to Study Autophagy

Frontiers in Cell and Developmental Biology, 2018
Growing amount of evidence in the last two decades highlight that macroautophagy (generally referred to as autophagy) is not only indispensable for survival in yeast but also equally important to maintain cellular quality control in higher eukaryotes as ...
Piyush Mishra, Veena Ammanathan, Ravi Manjithaya   +2 more
doaj   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

IgE-Crosslinking-Induced Luciferase Expression Test as a Sensitive Indicator of Anisakis Allergy

Antibodies
Background: Anisakis allergy has been increasing, and the diagnosis of it is based on specific serum IgE detection. Recently, the IgE-crosslinking-induced luciferase expression (EXiLE) test has been proposed as convenient tool for detecting functionally ...
Haruyo Akiyama, Masashi Niwa, Chisato Kurisaka, Yuto Hamada, Yuma Fukutomi, Reiko Teshima   +5 more
doaj   +1 more source

A Cell Line for Detection of Botulinum Neurotoxin Type B

Frontiers in Pharmacology, 2017
Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles.
Aleksander Rust, Ciara Doran, Rosalyn Hart, Thomas Binz, Paul Stickings, Dorothea Sesardic, Andrew A. Peden, Bazbek Davletov   +7 more
doaj   +1 more source

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

Advanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy, Chuan‐En Lu, Kai Liu, Audrey Gallud   +3 more
wiley   +1 more source

Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins

, 2021
Maximilian Hirschenberger, Manuel Hayn, Alexandre Laliberté, Lennart Koepke, Frank Kirchhoff, Konstantin M. J. Sparrer   +5 more
openalex   +1 more source

Anti-Inflammatory and Reactive Oxygen Species Suppression through Aspirin Pretreatment to Treat Hyperoxia-Induced Acute Lung Injury in NF-κB–Luciferase Inducible Transgenic Mice [PDF]

, 2020
Chuan‐Mu Chen, Yu‐Tang Tung, Chi-Hsuan Wei, Po-Ying Lee, Wei Chen   +4 more
openalex   +1 more source

NanoLuc Luciferase as a Fluorogen-Activating Protein for GFP Chromophore Based Fluorogens [PDF]

, 2023
Yulia A. Bogdanova, Elvira R. Zaitseva, Alexander Yu. Smirnov, Надежда С. Балеева, Alexey S. Gavrikov, Ivan N. Myasnyanko, Sergey A. Goncharuk, Erik F. Kot, Константин С. Минеев, Alexander S. Mishin, Михаил С. Баранов   +10 more
openalex   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Modification of H1N1 Influenza Luciferase Reporter Viruses Using StopGo Translation and/or Mouse-Adapted Mutations

Viruses
Reporter viruses are valuable tools for studying infections at the cellular level and in living animals. They also enable rapid, high-throughput antiviral drug screening and serological studies.
Po-Ling Chen, Guohua Yang, Chet Ojha, Balaji Banoth, Charles J. Russell   +4 more
doaj   +1 more source