Results 111 to 120 of about 45,597 (264)

Unveiling Mucorales infections: A cutting-edge longitudinal imaging approach for real-time infection and host-response monitoring in <i>Galleria mellonella</i> and mouse models. [PDF]

Virulence
Resendiz-Sharpe A, Kandelbauer C, Navarro Mendoza MI, Lemmens G, Scheler J, Bauer I, Vanhoffelen E, Seldeslachts L, de Herdt L, Michiels L, Belmans F, Nicolás FE, Lass-Flörl C, Lagrou K, Garre V, Binder U, Velde GV.   +16 more
europepmc   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Metastasis enables immunogenicity through migrasome-mediated antigen release. [PDF]

Nat Immunol
Jiang D, He J, Xie R, Shi M, Liu S, Jia H, Yang B, Ruan X, Tao X, Xiang Y, Chen Y, Jiao L, Feng X, Yu L.   +13 more
europepmc   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

A multiplex hextuple luciferase assay for advancing cellular signaling analysis in plant cells. [PDF]

Plant Commun
Song S, Darji S, Carter N, Venken KJT, Navarro S.   +4 more
europepmc   +1 more source

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source

Luciferase-induced immune activation prevents orthotopic K7M2luc osteosarcoma establishment in BALB/c mice. [PDF]

Radiol Oncol
Kupcic S, Kamensek U, Cemazar M, Tratar UL.   +3 more
europepmc   +1 more source

CYPRIDINA LUCIFERIN. PARTITION CHROMATOGRAPHY

Journal of Biological Chemistry, 1952
H S, MASON, E F, DAVIS
openaire   +2 more sources

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Development and Validation of a Method to Determine CYP4V2 Enzyme Activity in rAAV-hCYP4V2 Gene Therapy Products Using a Bioluminescent Substrate Assay. [PDF]

Molecules
Li Y, Fan W, Hou S, Ding Y, Jia X, Zhu X, Yuan Y, Zhang Y, Cao Y, Qin X, Liang C, Wang L.   +11 more
europepmc   +1 more source