Results 161 to 170 of about 44,149 (263)

Targeted Delivery of mRNA to the Heart via Extracellular Vesicles or Lipid Nanoparticles. [PDF]

J Extracell Vesicles
Nawaz M, Tangruksa B, Heydarkhan-Hagvall S, Kohl F, Garibotti HG, Jing Y, Payandeh Z, Reyahi A, Jennbacken K, Wiseman J, Hultin L, Lindfors L, Synnergren J, Valadi H.   +13 more
europepmc   +1 more source

Synthesis of Cypridina Luciferin and Related Compounds. VIII. : Improvement in the Synthesis of Cypridina Luciferin

YAKUGAKU ZASSHI, 1970
SUMI SUGIURA, SHOJI INOUE, TOSHIO GOTO
openaire   +2 more sources

Visualisation and Prediction of Phosphate Deficiency via Auto‐Glowing Plant Bioluminescent Sensors

Plant, Cell &Environment, EarlyView.
Ching‐Wen Chiu, Ya‐Fen Zhan, Ting‐Yang Lu, Liang‐Jie Chiu, Ya‐Ru Li, Cheng‐Jiun Huang, Hao‐Jun Lu, Huai‐Ji Huang, Alexander S. Mishin, Karen S. Sarkisyan, Ting‐Ying Wu, Chiu‐Han Hsiao, Ming‐Jung Liu   +12 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, Volume 13, Issue 35, 24 June 2026.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

A luminescent calcium biosensor enabling endpoint measurement of GPCR-mediated calcium signaling. [PDF]

Commun Biol
Doi K, Kise R, Shimizume K, Yanagawa M, Inoue A.   +4 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, Volume 13, Issue 35, 24 June 2026.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Development of a Glymphatic Pathway-based Rat Model for Cancer Metastasis from Brain to Lung. [PDF]

In Vivo
Sreejith A, Xiao H, Howson I, Bocchetta M, Aryal M.   +4 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, Volume 13, Issue 35, 24 June 2026.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

A Transgenic Mouse Model to Track MRC1-High Macrophages Using In Vivo Optical Imaging. [PDF]

Int J Mol Sci
Chawda C, Zambito G, Gaspar N, Schliehe C, Leenen PJM, Löwik C, Mezzanotte L.   +6 more
europepmc   +1 more source