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Isolation studies with Cypridina luciferin

Archives of Biochemistry and Biophysics, 1961
Abstract An attempt to isolate Cypridina luciferin in pure form has been made. The most promising approaches have involved the use of countercurrent distribution and membrane diffusion. Although the final objective was not realized because of instability and lack of material, the experiments strongly indicated the active chromophore to be a low ...
P, MARFEY, L C, CRAIG, E N, HARVEY
openaire   +2 more sources

Luciferin Regeneration in Firefly Bioluminescence via Proton-Transfer-Facilitated Hydrolysis, Condensation and Chiral Inversion.

ChemPhysChem, 2019
Firefly bioluminescence is produced via luciferin enzymatic reactions in luciferase. Luciferin has to be unceasingly replenished to maintain bioluminescence. How is the luciferin reproduced after it has been exhausted?
Yuan-Yuan Cheng, Yajun Liu
semanticscholar   +1 more source

Effect of &bgr;‐elemene on the kinetics of intracellular transport of d‐luciferin potassium salt (ABC substrate) in doxorubicin‐resistant breast cancer cells and the associated molecular mechanism

European Journal of Pharmaceutical Sciences, 2018
&NA; In order to explore the mechanism of the reversing multidrug resistance (MDR) phenotypes by &bgr;‐elemene (&bgr;‐ELE) in doxorubicin (DOX)‐resistant breast cancer cells (MCF‐7/DOX), both the functionality and quantity of the ABC transporters in MCF ...
Chaoyuan Tang   +7 more
semanticscholar   +1 more source

Bacterial and Other "Luciferins"

BioScience, 1975
Although luminous bacteria were among the very first of bioluminescent organisms to be made the subject of scientific research (Boyle 1667a,b), only recently has a satisfactory answer to one of the most puzzling aspects of bacterial luminescence become firmly established (McCapra and Hysert 1973, Dunn et al. 1973, Shimomura et al. 1972, 1974, Vigny and
Frank H. Johnson, Osamu Shimomura
openaire   +1 more source

2-S-cysteinylhydroquinone is an intermediate for the firefly luciferin biosynthesis that occurs in the pupal stage of the Japanese firefly, Luciola lateralis.

Bioorganic chemistry (Print), 2018
Firefly luciferin is a natural product that is well-known to function as the substrate of the bioluminescence reaction in luminous beetles. However, the details of the biosynthetic system are still unclear.
Shusei Kanie, R. Nakai, M. Ojika, Y. Oba
semanticscholar   +1 more source

Novel Heterocyclic Analogues of Firefly Luciferin

Biochemistry, 2012
Five novel firefly luciferin analogues in which the benzothiazole ring system of the natural substrate was replaced with benzimidazole, benzofuran, benzothiophene, benzoxazole, and indole were synthesized. The fluorescence, bioluminescence, and kinetic properties of the compounds were evaluated with recombinant Photinus pyralis wild type luciferase ...
Carolyn C, Woodroofe   +7 more
openaire   +2 more sources

Chemiluminescence of Firefly Luciferin without Enzyme

Science, 1962
We have been able to produce chemiluminescence in firefly luciferin without utilizing the enzyme luciferase. Following the analogous mechanism of the chemiluminescence of luminol in the organic solvent dimethyl sulfoxide, we have prepared synthetically the methyl ester of luciferin, the phosphate ester of luciferin and luciferyl adenylate ...
H H, SELIGER, W D, McELROY
openaire   +2 more sources

Multicolor Bioluminescence Obtained Using Firefly Luciferin

Current Topics in Medicinal Chemistry, 2016
Firefly bioluminescence is widely used in life science research as a useful analysis tool. For example, the adenosine-5`-triphosphate (ATP)-dependent enzymatic firefly bioluminescence reaction has long been utilized as a microbial monitoring tool. Rapid and sensitive firefly luciferin-luciferase combinations are used not only to measure cell viability ...
Masahiro, Kiyama   +5 more
openaire   +2 more sources

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