Results 111 to 120 of about 11,360 (208)

Lumefantrine drug selection regimen.

, 2012
Number of cycles during which V1S was cultured with varying Lumefantrine (LM) concentrations. In total, parasites were exposed to LM for 166 P. falciparum cycles, finally resulting in LM resistant V1SLM.
Jennifer Musyoki (181154), Jacob Lemieux (181156), Chris Newbold (181166), Leah Mwai (181144), Steven Muriithi (181152), Avi Feller (181159), Victor Masseno (181150), Theresa Feltwell (66997), Alexis Nzila (181169), Abdi Diriye (181147), Gunnar R. Mair (181162), Céline K. Carret (181171), Kevin Marsh (9406)   +12 more
core   +1 more source

Artemether-lumefantrine coadministration with antiretrovirals; population pharmacokinetics and dosing implications.

, 2014
AIM: Drug-drug interactions between antimalarial and antiretroviral drugs may influence antimalarial treatment outcomes. The aim of this study was to investigate the potential drug-drug interactions between the anti-malarial drugs; lumefantrine ...
Pauline Byakika‐Kibwika, Mohammed Lamorde, Concepta Merry, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning, Angela Äbelö, Ashton, M, Michael Ashton, Byakika-Kibwika, P, Nicholas J. White, Hanpithakpong, W, Abelö, A, Merry, C, Tarning, J, Warunee Hanpithakpong, Day, NP, White, NJ, Lamorde, M, Hoglund, RM   +19 more
core   +1 more source

Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda. [PDF]

Nat Med
Niaré K, Tafesse B, Treat M, Sadler JM, Okitwi M, Orena S, Asua V, Kreutzfeld O, Legac J, Marglous J, Nsobya SL, Yeka A, Richard D, Ferdig MT, Mukherjee A, Rosenthal PJ, Juliano JJ, Bailey JA, Conrad MD.   +18 more
europepmc   +1 more source

Structural and Functional Impact of the G340S Mutation in Plasmodium falciparum Ferredoxin NADP⁺ Reductase: In silico Analysis and Molecular Docking. [PDF]

Gates Open Res
Kiboi D, Muriithi B.
europepmc   +1 more source

Indole-based hybrids target both asexual parasites and gametocytes of <i>Plasmodium falciparum</i> and synergize with lumefantrine. [PDF]

Antimicrob Agents Chemother
Mohanty A, Nakabashi M, Dias BKM, Maiolini P, Delgado JAC, Quaglio KdS, Paixão MW, Garcia CRS.   +7 more
europepmc   +1 more source

Determination of Lumefantrine after Capillary Sampling onto Sampling Paper

, 2007
The antimalarial lumefantrine was first synthesised and registered in China and is now commercially available as a coformulated product together with artemether (Coartem®/Riamet®).
Annerberg, Anna, Blessborn, Daniel,, Björkman, Anders, Römsing, Susanne,, Sundquist, Daniel, Lindegårdh, Niklas, Bergqvist, Yngve,   +6 more
core  

Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda. [PDF]

Nat Commun
Nguyen TD, Zupko RJ, Conrad MD, Rukundo GB, Farinha CC, Asua VD, Tran KT, Grace DM, Rosenthal PJ, Agaba BB, Kamya MR, Opigo J, Boni MF.   +12 more
europepmc   +1 more source

Cross-border molecular epidemiology of Plasmodium falciparum drug susceptibility: insights from the Uganda-Democratic Republic of the Congo border. [PDF]

Malar J
Dilufwasayo PM, Balikagala B, Uchopa MA, Amaa JA, Ngoyi DM, Mita T.   +5 more
europepmc   +1 more source

Therapeutic efficacy of artemether-lumefantrine plus single low dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in a high transmission setting, Western Ethiopia. [PDF]

PLoS One
Deressa JD, Behaksra SW, Molla E, Letebo A, Shumie G, Adnew B, Alemayehu DH, Kassa FA, Seyoum T, Tafa EB, Woldekidan K, Ejigu LA, Huwe T, Keffale M, Bayissa GA, Koepfli C, Chala B, Asmamaw Y, Tadesse FG, Gadisa E.   +19 more
europepmc   +1 more source

Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review. [PDF]

EClinicalMedicine
Pandey AK, Bhandari RK, Charani E, Cohn J, Ghautare A, Märtson AG, Gadde U, Dlamini S, Miller M, Malhotra S, Tängdén T, Singh S, Mendelson M, Shafiq N.   +13 more
europepmc   +1 more source