Results 51 to 60 of about 3,948,840 (323)

The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification.

Journal of Thoracic Oncology, 2015
The 2015 World Health Organization (WHO) Classification of Tumors of the Lung, Pleura, Thymus and Heart has just been published with numerous important changes from the 2004 WHO classification. The most significant changes in this edition involve (1) use
W. Travis, E. Brambilla, A. Nicholson, Y. Yatabe, J. Austin, M. Beasley, L. Chirieac, S. Dacic, E. Duhig, D. Flieder, K. Geisinger, F. Hirsch, Y. Ishikawa, K. Kerr, M. Noguchi, G. Pelosi, C. Powell, M. Tsao, I. Wistuba   +18 more
semanticscholar   +1 more source

Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus

Frontiers in Immunology, 2019
Exposure of lupus-prone female NZBWF1 mice to respirable crystalline silica (cSiO2), a known human autoimmune trigger, initiates loss of tolerance, rapid progression of autoimmunity, and early onset of glomerulonephritis.
Abby D. Benninghoff, Melissa A. Bates, Melissa A. Bates, Preeti S. Chauhan, Kathryn A. Wierenga, Kathryn A. Wierenga, Kristen N. Gilley, Andrij Holian, Jack R. Harkema, Jack R. Harkema, James J. Pestka, James J. Pestka, James J. Pestka   +12 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Erlotinib in previously treated non-small-cell lung cancer.

New England Journal of Medicine, 2005
BACKGROUND We conducted a randomized, placebo-controlled, double-blind trial to determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival in non-small-cell lung cancer after the failure of first-line or second-line ...
F. Shepherd, J. Rodrigues Pereira, T. Ciuleanu, E. Tan, V. Hirsh, S. Thongprasert, D. Campos, Savitree Maoleekoonpiroj, M. Smylie, R. Martins, M. van Kooten, M. Dediu, B. Findlay, D. Tu, D. Johnston, A. Bezjak, G. Clark, P. Santabarbara, L. Seymour   +18 more
semanticscholar   +1 more source

Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement.

Journal of the American Medical Association (JAMA), 2021
Importance Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, and 135 720 persons died of the disease.
A. Krist, K. Davidson, C. Mangione, M. Barry, M. Cabana, A. Caughey, E. Davis, Katrina E. Donahue, Chyke A Doubeni, Martha Y. Kubik, C. Landefeld, Li Li, G. Ogedegbe, D. Owens, L. Pbert, Michael Silverstein, J. Stevermer, Chien-Wen Tseng, J. Wong   +18 more
semanticscholar   +1 more source

Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain); November 23rd-25th 2016; Session “Lung and development”

Journal of Pediatric and Neonatal Individualized Medicine, 2016
Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain); November 23rd-25th 2016; Session “Lung and development” ABS 1. AN OPEN LABEL, DOSE-ESCALATION STUDY OF LUCINACTANT FOR INHALATION DELIVERED VIA NASAL CONTINUOUS POSITIVE ...
--- Various Authors
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells

Frontiers in Immunology, 2018
Porcine Reproductive and Respiratory Syndrome virus (PRRSV) is an arterivirus responsible for highly contagious infection and huge economic losses in pig industry. Two species, PRRSV-1 and PRRSV-2 are distinguished, PRRSV-1 being more prevalent in Europe.
Elise Bordet, Fany Blanc, Mathieu Tiret, Elisa Crisci, Elisa Crisci, Edwige Bouguyon, Patricia Renson, Patricia Renson, Patricia Renson, Pauline Maisonnasse, Mickael Bourge, Jean-Jacques Leplat, Elisabetta Giuffra, Luc Jouneau, Isabelle Schwartz-Cornil, Olivier Bourry, Olivier Bourry, Nicolas Bertho   +17 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Perinatal respiratory infections and long term consequences

Journal of Pediatric and Neonatal Individualized Medicine, 2015
Respiratory syncytial virus (RSV) is the most important pathogen in the etiology of respiratory infections in early life. 50% of children are affected by RSV within the first year of age, and almost all children become infected within two years. Numerous
Luciana Indinnimeo, Valentina De Vittori
doaj   +1 more source