International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. [PDF]
, 2005 Lung cancer rates have peaked among men in many areas of the world, but rates among women continue to rise. Most lung cancers are squamous cell carcinoma, small cell carcinoma, or adenocarcinoma; trends vary according to type.
Bray, Freddie +3 more
core +1 more source
Cell Death and Differentiation, 2021 The prerequisite function of vimentin for the epithelial–mesenchymal transition (EMT) is not clearly elucidated yet. Here, we show that vimentin phosphorylated by PLK1, triggers TGF-β-signaling, which consequently leads to metastasis and PD-L1 expression
Hay-Ran Jang +6 more
semanticscholar +1 more source
MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]
, 2018 Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio +5 more
core +1 more source
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity
Genome Biology, 2021 Background Although using a blockade of programmed death-ligand 1 (PD-L1) to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy is limited for patients with solid tumors.
Shuang Qu +16 more
semanticscholar +1 more source
Effects of lncRNA PKD2-2-3 on cell proliferation, clone formation, migration, and invasion of lung adenocarcinoma [PDF]
Zhongguo aizheng zazhi, 2023 Background and purpose: Long non-coding RNA (lncRNA) is abnormally expressed in lung adenocarcinoma patients, and closely related to tumor occurrence, development and chemotherapy resistance.
JIA Liqing, GE Xiaolu, JIANG Lin, ZHOU Xiaoyan
doaj +1 more source
Cardiac Tamponade Secondary to Metastasis from Adenocarcinoma of the Parotid Gland [PDF]
, 2003 BACKGROUND: Metastatic involvement of pericardium producing cardiac tamponade is rare. When occurs it is mainly from the lung, breast and the neoplasms of the lymphoreticular system.
Barbetakis, Nikolaos G +5 more
core +4 more sources
Translational Lung Cancer Research, 2021 Background The biological role and clinical significance of transfer RNA-derived small RNAs (tsRNAs) remain largely unclear. The purpose of this study was to investigate the biological function, molecular mechanism, and clinical significance of tsRNA ...
F. Hu +8 more
semanticscholar +1 more source
GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma
BMC Cancer, 2018 Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei +6 more
doaj +1 more source
Histogram-based models on non-thin section chest CT predict invasiveness of primary lung adenocarcinoma subsolid nodules. [PDF]
, 2019 109 pathologically proven subsolid nodules (SSN) were segmented by 2 readers on non-thin section chest CT with a lung nodule analysis software followed by extraction of CT attenuation histogram and geometric features.
Dmytriw, Adam A +7 more
core +2 more sources
Hepatoid adenocarcinoma of the lung
Autopsy and Case Reports, 2013 Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
João Augusto dos Santos Martines +3 more
openaire +4 more sources