International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. [PDF]
, 2005 Lung cancer rates have peaked among men in many areas of the world, but rates among women continue to rise. Most lung cancers are squamous cell carcinoma, small cell carcinoma, or adenocarcinoma; trends vary according to type.
Bray, Freddie +3 more
core +1 more source
MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]
, 2018 Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio +5 more
core +1 more source
Pan-cancer classifications of tumor histological images using deep learning [PDF]
, 2020 Histopathological images are essential for the diagnosis of cancer type and selection of optimal treatment. However, the current clinical process of manual inspection of images is time consuming and prone to intra- and inter-observer variability. Here we
Caruana, Dennis +8 more
core +1 more source
Cell Death and Differentiation, 2021 The prerequisite function of vimentin for the epithelial–mesenchymal transition (EMT) is not clearly elucidated yet. Here, we show that vimentin phosphorylated by PLK1, triggers TGF-β-signaling, which consequently leads to metastasis and PD-L1 expression
Hay-Ran Jang +6 more
semanticscholar +1 more source
Cardiac Tamponade Secondary to Metastasis from Adenocarcinoma of the Parotid Gland [PDF]
, 2003 BACKGROUND: Metastatic involvement of pericardium producing cardiac tamponade is rare. When occurs it is mainly from the lung, breast and the neoplasms of the lymphoreticular system.
Barbetakis, Nikolaos G +5 more
core +4 more sources
MEK5 promotes lung adenocarcinoma [PDF]
European Respiratory Journal, 2018 MEK5 acts as an oncogenic driver in mice lung cancer and is pivotal for human lung adenocarcinoma http://ow.ly ...
S?nchez Fern?ndez, Adri?n +9 more
openaire +3 more sources
GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma
BMC Cancer, 2018 Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei +6 more
doaj +1 more source
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity
Genome Biology, 2021 Background Although using a blockade of programmed death-ligand 1 (PD-L1) to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy is limited for patients with solid tumors.
Shuang Qu +16 more
semanticscholar +1 more source
EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients
Chinese Journal of Lung Cancer, 2013 Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN +4 more
doaj +1 more source
Effects of lncRNA PKD2-2-3 on cell proliferation, clone formation, migration, and invasion of lung adenocarcinoma [PDF]
Zhongguo aizheng zazhi, 2023 Background and purpose: Long non-coding RNA (lncRNA) is abnormally expressed in lung adenocarcinoma patients, and closely related to tumor occurrence, development and chemotherapy resistance.
JIA Liqing, GE Xiaolu, JIANG Lin, ZHOU Xiaoyan
doaj +1 more source