Results 31 to 40 of about 637,902 (343)

Management of fungal lung disease in the immunocompromised [PDF]

open access: yesTherapeutic Advances in Respiratory Disease, 2011
Pulmonary mycoses are among the most feared infections encountered in immunocompromised patients. The problem is amplified by the increasing numbers of chronically immunocompromised patients that have substantially increased both the prevalence and clinical severity of infections caused by fungi.
Christopher H. Mody, Anowara Islam
openaire   +4 more sources

Update on Respiratory Fungal Infections in Cystic Fibrosis Lung Disease and after Lung Transplantation [PDF]

open access: yesJournal of Fungi, 2020
Cystic fibrosis is the most common autosomal-recessive metabolic disease in the Western world. Impaired trans-membrane chloride transport via the cystic fibrosis transmembrane conductance regulator (CFTR) protein causes thickened body fluids. In the respiratory system, this leads to chronic suppurative cough and recurrent pulmonary infective ...
Sabine Renner   +3 more
openaire   +3 more sources

Using Artificial Intelligence in Fungal Lung Disease: CPA CT Imaging as an Example [PDF]

open access: yesMycopathologia, 2021
AbstractThis positioning paper aims to discuss current challenges and opportunities for artificial intelligence (AI) in fungal lung disease, with a focus on chronic pulmonary aspergillosis and some supporting proof-of-concept results using lung imaging.
Elsa Angelini, Anand Shah
openaire   +4 more sources

Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases – Current Concepts and Potential Applications

open access: yesInternational Journal of COPD, 2020
Chitinases, enzymes that cleave chitin’s chain to low molecular weight chitooligomers, are widely distributed in nature. Mammalian chitinases belong to the 18-glycosyl-hydrolase family and can be divided into two groups: true chitinases with enzymatic ...
N. Przysucha, K. Górska, R. Krenke
semanticscholar   +1 more source

The Gut-Lung Axis in Health and Respiratory Diseases: A Place for Inter-Organ and Inter-Kingdom Crosstalks

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The gut and lungs are anatomically distinct, but potential anatomic communications and complex pathways involving their respective microbiota have reinforced the existence of a gut–lung axis (GLA).
R. Enaud   +6 more
semanticscholar   +1 more source

Lung cancer coexisting with Papiliotrema flavescens infection diagnosed by next-generation sequencing: a case report

open access: yesBMC Infectious Diseases, 2022
Background Papiliotrema flavescens is a rare environmental yeast, which has been isolated from air, trees, kernels of wheat and corn, fermenting soya sauce, and cerebrospinal fluid of patient with AIDS.
Siang Zhang   +5 more
doaj   +1 more source

Exposure to mold proteases stimulates mucin production in airway epithelial cells through Ras/Raf1/ERK signal pathway.

open access: yesPLoS ONE, 2020
Environmental mold (fungus) exposure poses a significant threat to public health by causing illnesses ranging from invasive fungal diseases in immune compromised individuals to allergic hypertensive diseases such as asthma and asthma exacerbation in ...
Xianxian Wu   +4 more
doaj   +1 more source

Infection prophylaxis and management of fungal infections in lung transplant

open access: yesAnnals of Translational Medicine, 2020
Lung transplantation has emerged as a lifesaving treatment for a wide range of advanced lung diseases. While the survival of lung transplant recipients continues to improve, infectious complications contribute substantially to morbidity and mortality ...
A. P. Villalobos, S. Husain
semanticscholar   +1 more source

PD-1 blockade improves survival and fungal clearance, induces pro-inflammatory lung cytokines and synergizes with caspofungin in a pulmonary aspergillosis model.

open access: yesJournal of Infectious Diseases, 2020
Pharmacological immune checkpoint blockade has revolutionized oncological therapies and its remarkable success has sparked interest in expanding checkpoint inhibitor therapy in infectious diseases.
S. Wurster   +8 more
semanticscholar   +1 more source

Pulmonary histoplasmoma: a disguised malady

open access: yesAutopsy and Case Reports, 2019
Histoplasmosis is a mycosis caused by the dimorphic fungus, Histoplasma capsulatum, which is transmitted via dust and aerosols. Lung involvement is the most common, with a varied clinical presentation.
Paulo Marcelo Pontes Gomes de Matos   +2 more
doaj   +1 more source

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