Results 11 to 20 of about 934,333 (350)

Multifaceted Roles of Ferroptosis in Lung Diseases

open access: yesFrontiers in Molecular Biosciences, 2022
Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is characterized by the accumulation of intracellular iron, exhaustion of glutathione, deactivation of glutathione peroxidase, and promotion of lipid peroxidation ...
Yi Li   +7 more
doaj   +2 more sources

Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases

open access: yesThoracic Cancer, 2020
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of defense of the airway and lungs against inhaled pollutants and pathogens.
Yu Cao   +4 more
doaj   +2 more sources

Fine particulate matter (PM2.5): The culprit for chronic lung diseases in China

open access: yesChronic Diseases and Translational Medicine, 2018
Air pollution is a world public health problem. Particulate matter (PM), a mix of solid and liquid particles in the air, becomes an increasing concern in the social and economic development of China.
Tao Li   +6 more
doaj   +2 more sources

Natural therapeutics and nutraceuticals for lung diseases: Traditional significance, phytochemistry, and pharmacology.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
BACKGROUND Lung diseases including chronic obstructive pulmonary disease (COPD), infections like influenza, acute respiratory distress syndrome (ARDS), asthma and pneumonia lung cancer (LC) are common causes of sickness and death worldwide due to their ...
M. Rahman   +20 more
semanticscholar   +1 more source

IL-17 Cytokines and Chronic Lung Diseases

open access: yesCells, 2022
IL-17 cytokines are expressed by numerous cells (e.g., gamma delta (γδ) T, innate lymphoid (ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the induction of cytokines and chemokines which mediate the recruitment of ...
F. Ritzmann   +4 more
semanticscholar   +1 more source

The Role of Macrophages in the Development of Acute and Chronic Inflammatory Lung Diseases

open access: yesCells, 2021
Macrophages play an important role in the innate and adaptive immune responses of organ systems, including the lungs, to particles and pathogens. Cumulative results show that macrophages contribute to the development and progression of acute or chronic ...
Jae-Won Lee   +7 more
semanticscholar   +1 more source

Role of Ferroptosis in Lung Diseases

open access: yesJournal of Inflammation Research, 2021
Ferroptosis is a new type of programmed cell death characterized by intracellular iron accumulation and lipid peroxidation that leads to oxidative stress and cell death.
Wenting Xu   +9 more
semanticscholar   +1 more source

Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

open access: yeseLife, 2021
Expression levels of CX3CR1 (C-X3-C motif chemokine receptor 1) on immune cells have significant importance in maintaining tissue homeostasis under physiological and pathological conditions.
Srinu Tumpara   +14 more
doaj   +1 more source

Recent Progress of Ferroptosis in Lung Diseases

open access: yesFrontiers in Cell and Developmental Biology, 2021
Ferroptosis is a new form of programmed cell death due to iron-dependent excess accumulation of lipid peroxides and differs from other programmed cell deaths in morphological and biochemical characteristics.
Shang Yu   +5 more
semanticscholar   +1 more source

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]

open access: yes, 2015
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter   +15 more
core   +2 more sources

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