Results 21 to 30 of about 3,148,779 (255)

Multifaceted Roles of Ferroptosis in Lung Diseases

Frontiers in Molecular Biosciences, 2022
Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is characterized by the accumulation of intracellular iron, exhaustion of glutathione, deactivation of glutathione peroxidase, and promotion of lipid peroxidation ...
Yi Li, Yi Li, Yi Li, Ying Yang, Ying Yang, Yongfeng Yang, Yongfeng Yang, Yongfeng Yang   +7 more
doaj   +1 more source

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1

Frontiers in Medicine, 2020
Smokers with apparently “healthy” lungs suffer from more severe and frequent viral respiratory infections, but the mechanisms underlying this observation are still unclear.
Olga Danov, Martin Wolff, Sabine Bartel, Sabine Bartel, Sebastian Böhlen, Helena Obernolte, Sabine Wronski, Danny Jonigk, Barbara Hammer, Draginja Kovacevic, Sebastian Reuter, Sebastian Reuter, Susanne Krauss-Etschmann, Susanne Krauss-Etschmann, Katherina Sewald   +14 more
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Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group

Respiratory Research, 2022
Introduction Despite improvements in medical science and public health, mortality of community-acquired pneumonia (CAP) has barely changed throughout the last 15 years.
Mathias W. Pletz, Andreas Vestergaard Jensen, Christina Bahrs, Claudia Davenport, Jan Rupp, Martin Witzenrath, Grit Barten-Neiner, Martin Kolditz, Sabine Dettmer, James D. Chalmers, Daiana Stolz, Norbert Suttorp, Stefano Aliberti, Wolfgang M. Kuebler, Gernot Rohde   +14 more
doaj   +1 more source

Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies

Scientific Reports, 2022
Non-alcoholic fatty liver disease (NAFLD) affects about 24% of the world's population. Progression of early stages of NAFLD can lead to the more advanced form non-alcoholic steatohepatitis (NASH), and ultimately to cirrhosis or liver cancer.
Fabian Heinemann, Peter Gross, Svetlana Zeveleva, Hu Sheng Qian, Jon Hill, Anne Höfer, Danny Jonigk, Anna Mae Diehl, Manal Abdelmalek, Martin C. Lenter, Steven S. Pullen, Paolo Guarnieri, Birgit Stierstorfer   +12 more
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Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan [PDF]

, 2014
Katsuya Onishi,1 Daisuke Yoshimoto,2 Gerry W Hagan,3 Paul W Jones4 1Onishi Heart Clinic, Mie, 2Medical Affairs Respiratory, GlaxoSmithKline KK, Tokyo, Japan; 3Independent Consultant, Marbella, Spain; 4Division of Clinical Science, St George's ...
Jones PW, Hagan, GW, Hagan GW, Onishi, K, Jones, PW, Onishi K, Yoshimoto D, Yoshimoto, D   +7 more
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Lung function in the general population : the complex interplay of variants in "Serpina1" and other genes with the environment [PDF]

, 2013
Background. One of the globally most frequent health problems are obstructive lung diseases such as asthma and chronic obstructive pulmonary disease.
Thun, Gian Andri
core   +1 more source

Early life origins of lung ageing : early life exposures and lung function decline in adulthood in two European cohorts aged 28-73 years [PDF]

, 2015
Early life environment is essential for lung growth and maximally attained lung function. Whether early life exposures impact on lung function decline in adulthood, an indicator of lung ageing, has scarcely been studied.; Spirometry data from two time ...
Svanes, C., Dratva, J., Norbäck D, Dan Norbäck (2143342), Villani, S., Gómez Real, Francisco, Dan Norbäck, Real, Francisco Gómez, Marco, Roberto de, Janson C, Dharmage, Shyamali C, Burdet, L., Jarvis, D, Villani S, de Marco, Roberto, Zemp, E., Accordini, Simone, Roberto de Marco, Julia Dratva, Elisabeth Zemp (142900), Accordini, S., Zemp, E, Deborah Jarvis (59834), Norbäck, D., Probst-Hensch, Nicole, Zemp, Elisabeth, Zemp, Elisabeth,, Probst-Hensch, N, Deborah Jarvis, Shyamali C. Dharmage (131486), Simona Villani, Pons, M, Joachim Heinrich (60421), Dharmage, S.C., Burdet, Luc, Luc Burdet (848789), Sunyer Deu, Jordi, Sunyer J, Accordini, Simone,, de Marco R, Dratva, Julia,, Jarvis, Deborah,, Simone Accordini (411992), Heinrich, Joachim,, Svanes, C, Marco Pons (848790), Dratva, J, Roberto de Marco (370210), Probst Hensch, Nicole, Christer Janson, Cecilie Svanes (59836), Thorarinn Gislason (508297), Heinrich, Joachim, Norbäck, Dan, Pons, M., Elisabeth Zemp, Heinrich, J., Julia Dratva (748527), Luc Burdet, Jarvis, Deborah, Villani, Simona, Nicole Probst-Hensch (520032), Real, FG, Jordi Sunyer, Dharmage SC, Villani, Simona,, Jarvis, D., de Marco, R., Dratva J, Accordini S, Pons M, Gislason, T., Probst-Hensch, N., Zemp E, Christer Janson (83414), Sunyer, J., Gislason, Thorarinn, Francisco Gómez Real (769225), Dharmage, Shyamali C.,, Real, Francisco Gomez,, Sunyer, Jordi,, Janson, Christer,, Sunyer, J, Janson, C., Thorarinn Gislason, Jarvis D, Svanes C, de Marco, Roberto,, Janson, C, Norback, D, Cecilie Svanes, Simona Villani (59831), de Marco, R, Burdet, Luc,, Pons, Marco,, Francisco Gómez Real, Real FG, Gislason, Thorarinn,, Shyamali C Dharmage, Norbäck, Dan,, Heinrich, J, Real, F.G., Simone Accordini, Joachim Heinrich, Janson, Christer, Dharmage, Shyamali C., Dratva, Julia, Jordi Sunyer (59833), Probst-Hensch N, Dharmage, SC, Pons, Marco, Sunyer, Jordi, Accordini, S, Gislason, T, Gislason T, Heinrich J, Svanes, Cecilie,, Villani, S, Probst-Hensch, Nicole,, Svanes, Cecilie, Nicole Probst-Hensch, Burdet, L, Marco Pons, Burdet L   +123 more
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A pilot study of the impact of high-frequency chest wall oscillation in chronic obstructive pulmonary disease patients with mucus hypersecretion [PDF]

, 2011
Indranil Chakravorty1, Kamaljit Chahal2, Gillian Austin21St George's Hospital, London, 2East and North Hertfordshire NHS Trust, Lister Hospital and Primary Care Trust, Stevenage, Hertfordshire, UKIntroduction: Chronic obstructive pulmonary ...
Chahal, K, Chakravorty, I, Chahal K, null Chahal, Austin G, Chakravorty I, Indranil Chakravorty, Austin, G, null Austin   +8 more
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The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions

Frontiers in Pharmacology, 2018
Neutrophils are the predominant immune cells in human blood possessing heterogeneity, plasticity and functional diversity. The activation and recruitment of neutrophils into inflamed tissue in response to stimuli are tightly regulated processes.
Sabina Janciauskiene, Sabina Janciauskiene, Sabine Wrenger, Stephan Immenschuh, Beata Olejnicka, Timm Greulich, Tobias Welte, Joanna Chorostowska-Wynimko   +7 more
doaj   +1 more source

Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study

Frontiers in Oncology, 2022
In the last decade, targeting the immune system became a promising therapy in advanced lung cancer stages. However, in a clinical follow-up, patient responses to immune checkpoint inhibitors widely differ.
Marc A. Schneider, Marc A. Schneider, Adriana Rozy, Sabine Wrenger, Sabine Wrenger, Petros Christopoulos, Petros Christopoulos, Thomas Muley, Thomas Muley, Michael Thomas, Michael Thomas, Michael Meister, Michael Meister, Tobias Welte, Tobias Welte, Joanna Chorostowska-Wynimko, Sabina Janciauskiene, Sabina Janciauskiene, Sabina Janciauskiene   +18 more
doaj   +1 more source