Results 21 to 30 of about 934,333 (350)

Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]

, 2013
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason, Martin, Jonathan, Ross, Joy R, Ross, Joy R., Wells, Athol U, Wells, Athol U.   +5 more
core   +1 more source

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

Nature Communications, 2021
Lung diseases, such as cystic fibrosis and COPD, are characterized by mucus obstruction and chronic airway inflammation, but their mechanistic link remains poorly understood.
Joschka Hey, Michelle Paulsen, R. Toth, D. Weichenhan, S. Butz, J. Schatterny, Reinhard Liebers, P. Lutsik, C. Plass, M. Mall   +9 more
semanticscholar   +1 more source

Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]

, 2016
Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM, Alipoor, SD, Garssen, J, Mirsaeidi, M, Mortaz, E, Movassaghi, M   +5 more
core   +10 more sources

New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]

, 2018
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A., Nayak, Ajay P., Penn, Raymond B   +2 more
core   +2 more sources

Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group

Respiratory Research, 2022
Introduction Despite improvements in medical science and public health, mortality of community-acquired pneumonia (CAP) has barely changed throughout the last 15 years.
Mathias W. Pletz, Andreas Vestergaard Jensen, Christina Bahrs, Claudia Davenport, Jan Rupp, Martin Witzenrath, Grit Barten-Neiner, Martin Kolditz, Sabine Dettmer, James D. Chalmers, Daiana Stolz, Norbert Suttorp, Stefano Aliberti, Wolfgang M. Kuebler, Gernot Rohde   +14 more
doaj   +1 more source

Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency? [PDF]

, 2017
Differentiating between chronic obstructive pulmonary disease (COPD) patients with normal (PiMM) or deficient (PiZZ) genetic variants of alpha-1 antitrypsin (A1AT) is important not only for understanding the pathobiology of disease progression but also ...
Carleo, Alfonso, Chorostowska-Wynimko, Joanna, Czajkowska-Malinowska, Małgorzata, Janciauskiene, Sabina, Koeck, Thomas, Mischak, Harald, Rozy, Adriana, Welte, Tobias   +7 more
core   +2 more sources

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1

Frontiers in Medicine, 2020
Smokers with apparently “healthy” lungs suffer from more severe and frequent viral respiratory infections, but the mechanisms underlying this observation are still unclear.
Olga Danov, Martin Wolff, Sabine Bartel, Sabine Bartel, Sebastian Böhlen, Helena Obernolte, Sabine Wronski, Danny Jonigk, Barbara Hammer, Draginja Kovacevic, Sebastian Reuter, Sebastian Reuter, Susanne Krauss-Etschmann, Susanne Krauss-Etschmann, Katherina Sewald   +14 more
doaj   +1 more source

Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies

Scientific Reports, 2022
Non-alcoholic fatty liver disease (NAFLD) affects about 24% of the world's population. Progression of early stages of NAFLD can lead to the more advanced form non-alcoholic steatohepatitis (NASH), and ultimately to cirrhosis or liver cancer.
Fabian Heinemann, Peter Gross, Svetlana Zeveleva, Hu Sheng Qian, Jon Hill, Anne Höfer, Danny Jonigk, Anna Mae Diehl, Manal Abdelmalek, Martin C. Lenter, Steven S. Pullen, Paolo Guarnieri, Birgit Stierstorfer   +12 more
doaj   +1 more source

Current concepts on the role of inflammation in COPD and lung cancer [PDF]

, 2009
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading cause of death, and both are associated with cigarette smoke exposure. It has been shown that 50–70% of patients diagnosed with lung cancer suffer from COPD, and reduced lung ...
Abdel-Aziz, Adenuga, Barnes, Bonomi, Brock, Campisi, Cao, Chen, Edirisinghe, Fong, Gebel, Goswami, Gozuacik, Gridelli, Hogg, Hogg, Hongwei Yao, Houghton, Irfan Rahman, Ito, Kamlah, Kasahara, Lee, Liu, Liu, Mannino, Marwick, Michaud, Moghaddam, Morris, Nozik-Grayck, Parimon, Pilette, Rajendrasozhan, Reiman, Rossi, Saitoh, Scherz-Shouval, Senderowicz, Siafakas, Sun, Takizawa, Tomita, Tsuji, van der Strate, van Houwelingen, Voelkel, Yamamoto, Yang, Yang, Yao, Yue   +51 more
core   +1 more source

Inhalation Technique Errors with Metered-Dose Inhalers Among Patients with Obstructive Lung Diseases: A Systematic Review and Meta-Analysis of U.S. Studies.

Chronic obstructive pulmonary diseases, 2019
Background Metered dose inhalers (MDIs) are commonly prescribed for inhalation therapy, but correct use is critical to promoting effective medication delivery.
Soojin Cho-Reyes, B. Celli, C. Dembek, Karen Yeh, M. Navaie   +4 more
semanticscholar   +1 more source