Results 21 to 30 of about 801,766 (352)

Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases [PDF]

open access: yes, 2020
The second messenger molecule 3′5′-cyclic adenosine monophosphate (cAMP) imparts several beneficial effects in lung diseases such as asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).
Cattani-Cavalieri, Isabella   +3 more
core   +2 more sources

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease. [PDF]

open access: yes, 2020
BACKGROUND:Chronic obstructive pulmonary disease and lung cancer are both life-limiting diseases that confer burden in the form of symptoms and affect functioning and quality of life.
Barnes-Harris, MM   +5 more
core   +2 more sources

Basement membranes in obstructive pulmonary diseases [PDF]

open access: yes, 2021
Increased and changed deposition of extracellular matrix proteins is a key feature of airway wall remodeling in obstructive pulmonary diseases, including asthma and chronic obstructive pulmonary disease.
Burgess, Janette K   +3 more
core   +1 more source

Sleep and Obstructive Lung Diseases [PDF]

open access: yesSleep Medicine Clinics, 2008
Asthma and chronic obstructive pulmonary disease (COPD) are common obstructive lung diseases affecting millions of people in the United States. As sleep disorders are also common, it is not surprising that many people with obstructive lung disease also suffer from sleep disorders. However, people with COPD and those with asthma have worse sleep quality
Michael E. Ezzie   +2 more
openaire   +3 more sources

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group

open access: yesRespiratory Research, 2022
Introduction Despite improvements in medical science and public health, mortality of community-acquired pneumonia (CAP) has barely changed throughout the last 15 years.
Mathias W. Pletz   +14 more
doaj   +1 more source

Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies

open access: yesScientific Reports, 2022
Non-alcoholic fatty liver disease (NAFLD) affects about 24% of the world's population. Progression of early stages of NAFLD can lead to the more advanced form non-alcoholic steatohepatitis (NASH), and ultimately to cirrhosis or liver cancer.
Fabian Heinemann   +12 more
doaj   +1 more source

Elastocapillary network model of inhalation [PDF]

open access: yesPhysical Review Research, 2, 043382 (2020), 2020
The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and overall air flow into the lungs.
arxiv   +1 more source

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

open access: yesNature Communications, 2021
Lung diseases, such as cystic fibrosis and COPD, are characterized by mucus obstruction and chronic airway inflammation, but their mechanistic link remains poorly understood.
Joschka Hey   +9 more
semanticscholar   +1 more source

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1

open access: yesFrontiers in Medicine, 2020
Smokers with apparently “healthy” lungs suffer from more severe and frequent viral respiratory infections, but the mechanisms underlying this observation are still unclear.
Olga Danov   +14 more
doaj   +1 more source

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