Results 31 to 40 of about 271,261 (306)

Immunological features of chronic obstructive pulmonary disease (COPD) induced by indoor pollution and cigarette smoke [PDF]

, 2012
Epigenetics is defined as heritable changes that affect gene expression without altering the DNA sequence. Epigenetic regulation of gene expression is facilitated through different mechanisms such as DNA methylation, histone modifications and RNA ...
Adcock, IM, Barnes, PJ, Heidarnazhad, H, Masjedi, MR, Mortaz, E   +4 more
core   +4 more sources

Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]

, 2019
Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix, Feldhaus, Felix W., Hubner, Ralf-Harto, Kuhnigk, Jan-Martin, Neumann, Konrad, Theilig, Dorothea Cornelia   +5 more
core   +1 more source

Type 2 responses determine skin rash during recombinant interleukin-2 therapy

Journal of Immunotoxicology
The skin is the organ most often affected by adverse drug reactions. Although these cutaneous adverse drug reactions (CADRs) often are mild, they represent a major burden for patients.
Charline Sommer, Vanessa Neuhaus, Patricia Gogesch, Thierry Flandre, Susann Dehmel, Katherina Sewald   +5 more
doaj   +1 more source

Evaluation of Functional Condition of Respiratory Muscles of Patients with a Complicated Bronchial Asthma Pathology and Chronic Obstructive Pulmonary Diseases [PDF]

, 2017
The aim of the research was to study the functional state of respiratory muscles and neuro-respiratory drive in patients with a combined pathology of bronchial asthma and chronic obstructive pulmonary disease.The functional condition of the respiratory ...
Feschenko, Y. (Yuriy), Nazarenko, K. (Ksenia)   +1 more
core   +2 more sources

Clinical characteristics of Japanese patients with chronic obstructive pulmonary disease (COPD) with comorbid interstitial lung abnormalities: A cross-sectional study.

PLoS ONE, 2020
Smoking-related interstitial lung abnormalities are different from specific forms of fibrosing lung disease which might be associated with poor prognoses.
Manabu Ono, Seiichi Kobayashi, Masakazu Hanagama, Masatsugu Ishida, Hikari Sato, Tomonori Makiguchi, Masaru Yanai   +6 more
doaj   +1 more source

Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases—Colonization or Disease?

Antibiotics, 2020
Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients with chronic lung diseases.
Monika Szturmowicz, Karina Oniszh, Dorota Wyrostkiewicz, Piotr Radwan-Rohrenschef, Dorota Filipczak, Anna Zabost   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Leveraging human precision cut lung slices for the study of human parainfluenza virus 3 infection

Respiratory Research
Human parainfluenza virus 3 is a highly abundant RNA virus that primarily affects young children, the elderly, and immunocompromised individuals, leading to severe lower respiratory infections and pneumonia.
Olga Danov, Philippe Vollmer Barbosa, Helena Obernolte, Maximilian Fuchs, Patrice Guillon, Larissa Dirr, Ibrahim El-Deeb, Meik Kunz, Leonie Hose, Gaël Martin, Fabian Röpken, Anna Zimmer, Lavinia Neubert, Danny Jonigk, Hans-Gerd Fieguth, Franziska Dahlmann, Sabine Wronski, Mark von Itzstein, Thomas Tschernig, Armin Braun, Katherina Sewald   +20 more
doaj   +1 more source

Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury

Frontiers in Immunology
IntroductionPulmonary ischemia-reperfusion (IR) injury (IRI) plays a significant role in various lung disorders and is a key factor in the development of primary graft dysfunction following lung transplantation.
Tomoyuki Nakagiri, Tomoyuki Nakagiri, Nadine R. Köhler, Sabina Janciauskiene, Sabina Janciauskiene, Sabina Janciauskiene, Lavinia Neubert, Lavinia Neubert, Ann-Kathrin Knöfel, Ann-Kathrin Knöfel, Pooja Pradhan, Arjang Ruhparwar, Fabio Ius, Fabio Ius, Stephan Immenschuh   +14 more
doaj   +1 more source