Results 31 to 40 of about 275,740 (301)

Immunological features of chronic obstructive pulmonary disease (COPD) induced by indoor pollution and cigarette smoke [PDF]

, 2012
Epigenetics is defined as heritable changes that affect gene expression without altering the DNA sequence. Epigenetic regulation of gene expression is facilitated through different mechanisms such as DNA methylation, histone modifications and RNA ...
Adcock, IM, Barnes, PJ, Heidarnazhad, H, Masjedi, MR, Mortaz, E   +4 more
core   +4 more sources

Type 2 responses determine skin rash during recombinant interleukin-2 therapy

Journal of Immunotoxicology
The skin is the organ most often affected by adverse drug reactions. Although these cutaneous adverse drug reactions (CADRs) often are mild, they represent a major burden for patients.
Charline Sommer, Vanessa Neuhaus, Patricia Gogesch, Thierry Flandre, Susann Dehmel, Katherina Sewald   +5 more
doaj   +1 more source

Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases—Colonization or Disease?

Antibiotics, 2020
Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients with chronic lung diseases.
Monika Szturmowicz, Karina Oniszh, Dorota Wyrostkiewicz, Piotr Radwan-Rohrenschef, Dorota Filipczak, Anna Zabost   +5 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Clinical characteristics of Japanese patients with chronic obstructive pulmonary disease (COPD) with comorbid interstitial lung abnormalities: A cross-sectional study.

PLoS ONE, 2020
Smoking-related interstitial lung abnormalities are different from specific forms of fibrosing lung disease which might be associated with poor prognoses.
Manabu Ono, Seiichi Kobayashi, Masakazu Hanagama, Masatsugu Ishida, Hikari Sato, Tomonori Makiguchi, Masaru Yanai   +6 more
doaj   +1 more source

Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]

, 2019
Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix, Feldhaus, Felix W., Hubner, Ralf-Harto, Kuhnigk, Jan-Martin, Neumann, Konrad, Theilig, Dorothea Cornelia   +5 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Leveraging human precision cut lung slices for the study of human parainfluenza virus 3 infection

Respiratory Research
Human parainfluenza virus 3 is a highly abundant RNA virus that primarily affects young children, the elderly, and immunocompromised individuals, leading to severe lower respiratory infections and pneumonia.
Olga Danov, Philippe Vollmer Barbosa, Helena Obernolte, Maximilian Fuchs, Patrice Guillon, Larissa Dirr, Ibrahim El-Deeb, Meik Kunz, Leonie Hose, Gaël Martin, Fabian Röpken, Anna Zimmer, Lavinia Neubert, Danny Jonigk, Hans-Gerd Fieguth, Franziska Dahlmann, Sabine Wronski, Mark von Itzstein, Thomas Tschernig, Armin Braun, Katherina Sewald   +20 more
doaj   +1 more source

Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosisResearch in context

EBioMedicine
Summary: Background: Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator, CFTR, an epithelial anion transport protein, responsible for, inter alia, sputum viscoelasticity in the lung.
Alexander Uden, Inga Dunsche, Sabina Janciauskiene, Simon Gräber, Longhua Feng, Stephanie Tamm, Silke Hedtfeld, Gesa Stege, Kirsten Jahn, Julia Kontsendorn, Nadine Alfeis, Iris Kühbandner, Rebecca Minso, Christian Dopfer, Matthias Griese, Olaf Sommerburg, Felix C. Ringshausen, Lutz Nährlich, Gesine Hansen, Tobias Welte, Peter Braubach, Marcus A. Mall, Burkhard Tümmler, Anna-Maria Dittrich, Frauke Stanke, Josje Altenburg, Els Aertgeerts, Vera Bauer, Johanna M.W. van den Berg, Sebastian F.N. Bode, Carlo Castellani, Raphael Chiron, Owen Dempsey, Angelika Dübbers, Johannes Eder, Helmut Ellemunter, Mary Herzig, Andrea Lakatos-Krepcik, Ulrika Lindberg, Jan ter Maaten, Henry Mazurek, Paola Melotti, Rita Francesca Padoan, Caroline Raynal, Sabina Seehofer, Nicholas J. Simmonds, Christina Smaczny, Prasima Srivastava, Nathalie Stremler, Fiona Thomson, Maria Dolores Pastor Vivero, Paul Vöhringer, Nadine Wollscheid, Domenique D. Zomer-van Ommen   +53 more
doaj   +1 more source

Bronchiolitis obliterans. [PDF]

, 1989
Bronchiolitis obliterans in the adult patient is a relatively uncommon and vexing clinical entity. This confusion results because this pathologic finding occurs in a variety of diverse clinical settings.
King, TE
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