Results 51 to 60 of about 184,952 (311)

Clinical characteristics of Japanese patients with chronic obstructive pulmonary disease (COPD) with comorbid interstitial lung abnormalities: A cross-sectional study.

PLoS ONE, 2020
Smoking-related interstitial lung abnormalities are different from specific forms of fibrosing lung disease which might be associated with poor prognoses.
Manabu Ono, Seiichi Kobayashi, Masakazu Hanagama, Masatsugu Ishida, Hikari Sato, Tomonori Makiguchi, Masaru Yanai   +6 more
doaj   +1 more source

Monitoring pulmonary rehabilitation and long-term oxygen therapy for people with chronic obstructive pulmonary disease (COPD) [PDF]

, 2013
This report outlines a proposed approach to monitoring access to, and utilisation of, pulmonary rehabilitation and long term oxygen therapy, by capitalising on existing data sources and identifying data development opportunities.SummaryChronic ...
Guy Marks
core  

Comparison of Platelet Indices in Patients with Obstructive Sleep Apnea and Obstructive Lung Diseases + Obstructive Sleep Apnea Syndrome [PDF]

Introduction: We aimed to observe the changes in platelet activities in patients with obstructive sleep apnea (OSA) and obstructive lung diseases + obstructive sleep apnea (OLDOSA) syndrome.
Fuat Erel, Mustafa Çolak, Nurhan Sarıoğlu, Gülden Deniz Aksu, Hikmet Çoban   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury

Frontiers in Immunology
IntroductionPulmonary ischemia-reperfusion (IR) injury (IRI) plays a significant role in various lung disorders and is a key factor in the development of primary graft dysfunction following lung transplantation.
Tomoyuki Nakagiri, Tomoyuki Nakagiri, Nadine R. Köhler, Sabina Janciauskiene, Sabina Janciauskiene, Sabina Janciauskiene, Lavinia Neubert, Lavinia Neubert, Ann-Kathrin Knöfel, Ann-Kathrin Knöfel, Pooja Pradhan, Arjang Ruhparwar, Fabio Ius, Fabio Ius, Stephan Immenschuh   +14 more
doaj   +1 more source

Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases—Colonization or Disease?

Antibiotics, 2020
Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients with chronic lung diseases.
Monika Szturmowicz, Karina Oniszh, Dorota Wyrostkiewicz, Piotr Radwan-Rohrenschef, Dorota Filipczak, Anna Zabost   +5 more
doaj   +1 more source

A pilot study of the impact of high-frequency chest wall oscillation in chronic obstructive pulmonary disease patients with mucus hypersecretion

, 2011
Indranil Chakravorty1, Kamaljit Chahal2, Gillian Austin21St George's Hospital, London, 2East and North Hertfordshire NHS Trust, Lister Hospital and Primary Care Trust, Stevenage, Hertfordshire, UKIntroduction: Chronic obstructive pulmonary ...
Chahal, K, Chakravorty, I, Chahal K, null Chahal, Austin G, Chakravorty I, Indranil Chakravorty, Austin, G, null Austin   +8 more
core   +1 more source

Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2011
Chronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators.
Hongwei Yao, Yao, Hongwei, Rahman, Irfan, Irfan Rahman   +3 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source