Results 61 to 70 of about 934,333 (350)

Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review

International Journal of Environmental Research and Public Health, 2018
Many studies have been undertaken to reveal how tobacco smoke skews immune responses contributing to the development of chronic obstructive pulmonary disease (COPD) and other lung diseases. Recently, environmental tobacco smoke (ETS) has been linked with
Agnieszka Strzelak, Aleksandra Ratajczak, Aleksander Adamiec, W. Feleszko   +3 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Clinical characteristics of Japanese patients with chronic obstructive pulmonary disease (COPD) with comorbid interstitial lung abnormalities: A cross-sectional study.

PLoS ONE, 2020
Smoking-related interstitial lung abnormalities are different from specific forms of fibrosing lung disease which might be associated with poor prognoses.
Manabu Ono, Seiichi Kobayashi, Masakazu Hanagama, Masatsugu Ishida, Hikari Sato, Tomonori Makiguchi, Masaru Yanai   +6 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosisResearch in context

EBioMedicine
Summary: Background: Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator, CFTR, an epithelial anion transport protein, responsible for, inter alia, sputum viscoelasticity in the lung.
Alexander Uden, Inga Dunsche, Sabina Janciauskiene, Simon Gräber, Longhua Feng, Stephanie Tamm, Silke Hedtfeld, Gesa Stege, Kirsten Jahn, Julia Kontsendorn, Nadine Alfeis, Iris Kühbandner, Rebecca Minso, Christian Dopfer, Matthias Griese, Olaf Sommerburg, Felix C. Ringshausen, Lutz Nährlich, Gesine Hansen, Tobias Welte, Peter Braubach, Marcus A. Mall, Burkhard Tümmler, Anna-Maria Dittrich, Frauke Stanke, Josje Altenburg, Els Aertgeerts, Vera Bauer, Johanna M.W. van den Berg, Sebastian F.N. Bode, Carlo Castellani, Raphael Chiron, Owen Dempsey, Angelika Dübbers, Johannes Eder, Helmut Ellemunter, Mary Herzig, Andrea Lakatos-Krepcik, Ulrika Lindberg, Jan ter Maaten, Henry Mazurek, Paola Melotti, Rita Francesca Padoan, Caroline Raynal, Sabina Seehofer, Nicholas J. Simmonds, Christina Smaczny, Prasima Srivastava, Nathalie Stremler, Fiona Thomson, Maria Dolores Pastor Vivero, Paul Vöhringer, Nadine Wollscheid, Domenique D. Zomer-van Ommen   +53 more
doaj   +1 more source

Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases—Colonization or Disease?

Antibiotics, 2020
Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients with chronic lung diseases.
Monika Szturmowicz, Karina Oniszh, Dorota Wyrostkiewicz, Piotr Radwan-Rohrenschef, Dorota Filipczak, Anna Zabost   +5 more
doaj   +1 more source

Comorbidities of patients in tiotropium clinical trials : comparison with observational studies of patients with chronic obstructive pulmonary disease [PDF]

, 2015
Acknowledgments The authors are fully responsible for all content and editorial decisions made, were involved at all stages of manuscript development, and have approved the final version for publication.
Celli, Bartolome, Metzdorf, Norbert, Miravitlles, Marc, Price, David, Rabe, Klaus F, Schmidt, Hendrik   +5 more
core   +1 more source

The roles of exosomal miRNAs and lncRNAs in lung diseases

Signal Transduction and Targeted Therapy, 2019
An increasing number of studies have reported that exosomes released from various cells can serve as mediators of information exchange between different cells.
Yang Li, Zhengrong Yin, Jinshuo Fan, Siyu Zhang, Weibing Yang   +4 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Obstructive lung disease

, 2018
Abstract This chapter guides the reader on the diagnosis and management of obstructive lung disease in hospitalized patients.
Yuranga Weerakkody, Andrew Murphy, David Luong   +2 more
openaire   +2 more sources