Results 61 to 70 of about 3,148,779 (255)

Comparison of Platelet Indices in Patients with Obstructive Sleep Apnea and Obstructive Lung Diseases + Obstructive Sleep Apnea Syndrome [PDF]

Introduction: We aimed to observe the changes in platelet activities in patients with obstructive sleep apnea (OSA) and obstructive lung diseases + obstructive sleep apnea (OLDOSA) syndrome.
Fuat Erel, Mustafa Çolak, Nurhan Sarıoğlu, Gülden Deniz Aksu, Hikmet Çoban   +4 more
core   +1 more source

Association of German Bronchiectasis Registry participation with disease course

ERJ Open Research
Background Bronchiectasis research has advanced significantly through international and national registries, such as the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) registry, revealing crucial insights into the disease's
Jessica Rademacher, Felix C. Ringshausen, Sivagurunathan Sutharsan, Gernot Rohde, Annegret Zurawski, Sarah Sieber, Grit Barten-Neiner, Nina Adaskina, Isabell Pink, Pontus Mertsch, Borghild Grün, Stefan Dargel, Katarina Ludwig, Andrés de Roux, Ralf Otto-Knapp, Hartmut Lode, Christian Gogoll, Meike Probst, Frank Herrmann, Axel Overlack, Stefan Pabst, Urte Sommerwerck, Harald Vehar, Stefan Blaas, Bernhard Schaaf, Martin Kolditz, Sivagurunathan Sutharsan, Peter Kardos, Achim Grünewaldt, Stephan Sorichter, Tobias Scholz, Marco Idzko, Moritz Mohadjer, Stephan Eisenmann, Sven P. Aries, Johannes Lauer-Hermfisse, Sabine Kampf, Felix C. Ringshausen, Sabine Wege, Felix Herth, Santiago Ewig, Christian Reinhardt, Stefan Andreas, Christian Schumann, Ingrid Bobis, Thomas Bahmer, Rita Fey, Martin Jüch, Axel T. Kempa, Erika Piirsoo, Benjamin Klapdor, Pontus Mertsch, Bernhard Schmidt, Holger Hein, Peter Haidl, Jorge Fernando Gamarra   +55 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke [PDF]

, 2009
The activation of transcription factor NF-kappaB is controlled by two main pathways: the classical canonical (RelA/p65-p50)- and the alternative noncanonical (RelB/p52)-NF-kappaB pathways.
Edirisinghe, Indika, Sime, Patricia J, Rajendrasozhan, Saravanan, Valvo, Samantha, McCabe Jr., Michael J, Bulger, Michael, Yao, Hongwei, Rahman, Irfan, Yang, Se-Ran, Li, Jian-Dong, Chung, Sangwoon, Fromm, George, Phipps, Richard P   +12 more
core   +1 more source

Pneumococcal pneumonia in adults – re-emergence of vaccine serotypes: a prospective multicenter cohort study in Germany, 2020–2023

Pneumonia
The main burden of non-invasive pneumococcal diseases in adults is largely due to community-acquired pneumonia (CAP). This study aimed to investigate the distribution and dynamics of pneumococcal vaccine serotypes and to determine the proportion of CAP ...
Christina Bahrs, Norman Rose, Grit Barten-Neiner, Carolin Fleischmann-Struzek, Mark P. G. van der Linden, Gernot Rohde, Jan Rupp, Martin Witzenrath, Jessica Rademacher, Mathias W. Pletz, the CAPNETZ Study Group   +10 more
doaj   +1 more source

Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosisResearch in context

EBioMedicine
Summary: Background: Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator, CFTR, an epithelial anion transport protein, responsible for, inter alia, sputum viscoelasticity in the lung.
Alexander Uden, Inga Dunsche, Sabina Janciauskiene, Simon Gräber, Longhua Feng, Stephanie Tamm, Silke Hedtfeld, Gesa Stege, Kirsten Jahn, Julia Kontsendorn, Nadine Alfeis, Iris Kühbandner, Rebecca Minso, Christian Dopfer, Matthias Griese, Olaf Sommerburg, Felix C. Ringshausen, Lutz Nährlich, Gesine Hansen, Tobias Welte, Peter Braubach, Marcus A. Mall, Burkhard Tümmler, Anna-Maria Dittrich, Frauke Stanke, Josje Altenburg, Els Aertgeerts, Vera Bauer, Johanna M.W. van den Berg, Sebastian F.N. Bode, Carlo Castellani, Raphael Chiron, Owen Dempsey, Angelika Dübbers, Johannes Eder, Helmut Ellemunter, Mary Herzig, Andrea Lakatos-Krepcik, Ulrika Lindberg, Jan ter Maaten, Henry Mazurek, Paola Melotti, Rita Francesca Padoan, Caroline Raynal, Sabina Seehofer, Nicholas J. Simmonds, Christina Smaczny, Prasima Srivastava, Nathalie Stremler, Fiona Thomson, Maria Dolores Pastor Vivero, Paul Vöhringer, Nadine Wollscheid, Domenique D. Zomer-van Ommen   +53 more
doaj   +1 more source

The role of airway infection in chronic obstructive pulmonary disease [PDF]

, 2006
PhDThis. thesis examines the role of respiratory bacterial and viral infection in the natural history of Chronic Obstructive Pulmonary Disease. The rationale for this study is basedu pon previous data demonstratingt hat airway bacterial colonisationi s
Wilkinson, Thomas Michael Alan
core   +4 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review [PDF]

, 2009
Exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the natural history of this prevalent and devastating condition. This review provides a concise, state of the art summary on prevention and management of exacerbations.
Hurst, JR, Hurst John R, Wedzicha Jadwiga A, Wedzicha, JA, John R Hurst, Jadwiga A Wedzicha   +5 more
core   +2 more sources

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source