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The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions
Frontiers in Pharmacology, 2018 Neutrophils are the predominant immune cells in human blood possessing heterogeneity, plasticity and functional diversity. The activation and recruitment of neutrophils into inflamed tissue in response to stimuli are tightly regulated processes.
Sabina Janciauskiene +7 more
doaj +1 more source
Obstructive Lung Diseases in HIV: A Clinical Review and Identification of Key Future Research Needs
Seminars in Respiratory and Critical Care Medicine, 2016 HIV infection has shifted from what was once a disease directly impacting short-term mortality to what is now a chronic illness controllable in the era of effective combination antiretroviral therapy (ART).
M. Drummond +2 more
semanticscholar +1 more source
Exosomal Long Non-Coding RNAs in Lung Diseases
International Journal of Molecular Sciences, 2020 Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their secretion within exosomes are a window that could further explain the regulation, the sustaining, and the spread of lung diseases.
C. Poulet +6 more
semanticscholar +1 more source
Pulmonary functions in sewage workers [PDF]
, 2022 Background: Occupational lung diseases in sewage workers have not received sufficient attention, despite chronic exposure to noxious material. We aimed to describe the pulmonary function testing pattern of sewage workers with special emphasis on ...
Asagaonkar, Dileep +5 more
core +2 more sources
New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]
, 2018 Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A. +2 more
core +2 more sources
Current concepts on the role of inflammation in COPD and lung cancer [PDF]
, 2009 Chronic obstructive pulmonary disease (COPD) and lung cancer are leading cause of death, and both are associated with cigarette smoke exposure. It has been shown that 50–70% of patients diagnosed with lung cancer suffer from COPD, and reduced lung ...
Abdel-Aziz +51 more
core +1 more source
Significance of the microbiome in obstructive lung disease [PDF]
Thorax, 2012 The composition of the lung microbiome contributes to both health and disease, including obstructive lung disease. Because it has been estimated that over 70% of the bacterial species on body surfaces cannot be cultured by currently available techniques, traditional culture techniques are no longer the gold standard for microbial investigation ...
Fernando J. Martinez +15 more
openaire +3 more sources
Computational modeling of the obstructive lung diseases asthma and COPD
Journal of Translational Medicine, 2014 Asthma and chronic obstructive pulmonary disease (COPD) are characterized by airway obstruction and airflow limitation and pose a huge burden to society.
K. Burrowes, T. Doel, C. Brightling
semanticscholar +1 more source
Hybrid Deep Learning for Detecting Lung Diseases from X-ray Images [PDF]
Informatics in Medicine Unlocked, 2020, 2020 Lung disease is common throughout the world. These include chronic obstructive pulmonary disease, pneumonia, asthma, tuberculosis, fibrosis, etc. Timely diagnosis of lung disease is essential. Many image processing and machine learning models have been developed for this purpose.
arxiv +1 more source
Phenotypes of obstructive lung disease [PDF]
The Clinical Respiratory Journal, 2008 AbstractRecently, there has been much emphasis on the fact that there are many different phenotypes in asthma and chronic obstructive pulmonary disease (COPD). The aim of this review is to investigate some aspects of phenotyping in these two diseases.Epidemiological studies show a quite different risk factor pattern in allergic and non‐allergic asthma.
openaire +3 more sources