Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
The effect of residential urban greenness on allergic respiratory diseases in youth: A narrative review [PDF]
Background: Environmental exposures across the life course may be a contributor to the increased worldwide prevalence of respiratory and allergic diseases occurring in the last decades.
Asta F+5 more
core +1 more source
Constrictive bronchiolitis obliterans in patient with Castelman’s disease
A 37-year-old woman with hialin- vascular type Castelman’s disease (CD) localised in the retroperitoneal region, incompletely resected, developed progressive dyspnoea. The chest radiograph taken 3 months before the operation was normal. The chest CT scan
E. Radzikowska+3 more
doaj +1 more source
Characterization of the PF-ILD phenotype in patients with advanced pulmonary sarcoidosis
Background Advanced pulmonary sarcoidosis causes significant morbidity and can lead to death. Large trials demonstrated efficacy of antifibrotics in patients with progressive fibrosing interstitial lung diseases (PF-ILD), including a few with sarcoidosis.
M. C. Schimmelpennink+7 more
doaj +1 more source
Self-proning in COVID-19 patients on low-flow oxygen therapy: a cluster randomised controlled trial
Rationale and objectives Prone positioning as a complement to oxygen therapy to treat hypoxaemia in coronavirus disease 2019 (COVID-19) pneumonia in spontaneously breathing patients has been widely adopted, despite a lack of evidence for its benefit.
Aileen Kharat+10 more
doaj +1 more source
AI-Decision Support System Interface Using Cancer Related Data for Lung Cancer Prognosis [PDF]
Until the beginning of 2021, lung cancer is known to be the most common cancer in the world. The disease is common due to factors such as occupational exposure, smoking and environmental pollution. The early diagnosis and treatment of the disease is of great importance as well as the prevention of the causes that cause the disease.
arxiv
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil. NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM+7 more
core
CEA, CYFRA 21-1, NSE, and ProGRP in the diagnosis of lung cancer: a multivariate approach [PDF]
We retrospectively studied the single and combined diagnostic value of carcinoembryonic antigen (CEA), cytokeratin fragment 19 (CYFRA 21-1), neuron specific enolase (NSE) and pro-gastrin-releasing peptide (ProGRP), which were routinely analysed in ...
Barak+21 more
core +1 more source
Inception-Based Network and Multi-Spectrogram Ensemble Applied For Predicting Respiratory Anomalies and Lung Diseases [PDF]
This paper presents an inception-based deep neural network for detecting lung diseases using respiratory sound input. Recordings of respiratory sound collected from patients are firstly transformed into spectrograms where both spectral and temporal information are well presented, referred to as front-end feature extraction.
arxiv