Results 81 to 90 of about 11,428,692 (412)

Both T and B cells are indispensable for the development of a PBMC transfer-induced humanized mouse model for SSc

Arthritis Research & Therapy, 2022
Background Recently, a novel humanized mouse model for systemic sclerosis (SSc) was established by transferring peripheral blood mononuclear cells (PBMC) from patients with SSc to Rag2 −/− Il2rg −/− immunodeficient mice. Here, we aimed to investigate the
Yaqing Shu, Xiaoyang Yue, Jacqueline Wax, Brigitte Kasper, Junping Yin, Xiaoqing Wang, Liang Zhang, Marjan Ahmadi, Harald Heidecke, Antje Müller, Peter Lamprecht, Xinhua Yu, Gabriela Riemekasten, Frank Petersen   +13 more
doaj   +1 more source

Atypical Pulmonary Tuberculosis as the First Manifestation of Advanced HIV Disease—Diagnostic Difficulties

Diagnostics, 2022
Tuberculosis (TB) is the leading cause of morbidity, hospitalisations, and mortality in people living with HIV (PLWH). The lower CD4+ T-lymphocyte count in the course of HIV infection, the higher risk of active TB, and the higher odds for atypical ...
Aneta Kacprzak, Karina Oniszh, Regina Podlasin, Maria Marczak, Iwona Cielniak, Ewa Augustynowicz-Kopeć, Witold Tomkowski, Monika Szturmowicz   +7 more
doaj   +1 more source

Comorbidities in unclassifiable interstitial lung disease

Respiratory Research, 2022
Background Comorbidities are common in interstitial lung diseases (ILD) and have an important association with survival, but the frequency and prognostic impact of comorbidities in unclassifiable interstitial lung disease (uILD) remains elusive. We aimed
Thomas Skovhus Prior, Charlotte Hyldgaard, Sebastiano Emanuele Torrisi, Sissel Kronborg-White, Claudia Ganter, Elisabeth Bendstrup, Michael Kreuter   +6 more
doaj   +1 more source

Recent advances in interstitial lung disease research [PDF]

, 2006
The interstitial lung diseases are a diverse collection of disorders characterized by impaired gas exchange, restricted physiology on lung function testing, and diffuse parenchymal lung infiltrates on radiography.
Vassallo, Robert
core  

Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network

IEEE Transactions on Medical Imaging, 2016
Automated tissue characterization is one of the most crucial components of a computer aided diagnosis (CAD) system for interstitial lung diseases (ILDs). Although much research has been conducted in this field, the problem remains challenging.
M. Anthimopoulos, S. Christodoulidis, L. Ebner, A. Christe, S. Mougiakakou   +4 more
semanticscholar   +1 more source

Autoinflammatory disease in the lung [PDF]

Immunology, 2018
SummaryAscertaining the dominant cell type driving an immunological disease is essential to understanding the causal pathology and, therefore, selecting or developing an effective treatment. Classifying immunological diseases in this way has led to successful treatment regimens for many monogenic diseases; however, when the dominant cell type is ...
Scambler, T, Holbrook, J, Savic, S, McDermott, MF, Peckham, D   +4 more
openaire   +3 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Neutrophil-to-Lymphocyte and Platelet Ratio (N/LP Ratio), a Reliable Criterion for Predicting In-Hospital Mortality in Both Genders Infected With SARS-CoV-2

Mediators of Inflammation
Conclusion: A reliable predictor in the current study of men and women with COVID-19 was N/LP ratio.
Jafar Mohammadshahi, Hassan Ghobadi, Afshan Shargi, Hossein Moradkhani, Hamed Rezaei, Mahur Kazemy, Mohammad Reza Aslani   +6 more
doaj   +1 more source

Lung Ultrasonography in the Evaluation of Late Sequelae of COVID-19 Pneumonia—A Comparison with Chest Computed Tomography: A Prospective Study

Viruses
The onset of the COVID-19 pandemic allowed physicians to gain experience in lung ultrasound (LUS) during the acute phase of the disease. However, limited data are available on LUS findings during the recovery phase.
Katarzyna Zimna, Małgorzata Sobiecka, Jacek Wakuliński, Dorota Wyrostkiewicz, Ewa Jankowska, Monika Szturmowicz, Witold Z. Tomkowski   +6 more
doaj   +1 more source

Evaluation of cardiomyopathy diagnosis in heart transplant recipients: comparison of echocardiographic and pathologic classification

The Egyptian Heart Journal, 2021
Background Definite diagnosis of cardiomyopathy types can be challenging in end-stage disease process. New growing data have suggested that there is inconsistency between echocardiography and pathology in defining type of cardiomyopathy before and after ...
Neda Behzadnia, Babak Sharif-Kashani, Zargham Hossein Ahmadi, Farah Naghashzadeh, Atosa Dorudinia, Alireza Jahangirifard, Hamoun Hamarz, Payam Abbasi   +7 more
doaj   +1 more source