Results 41 to 50 of about 14,390,763 (310)

SARS-CoV-2 Neutralizing Antibodies: A Network Meta-Analysis across Vaccines

Vaccines, 2021
Background: There are no studies providing head-to-head comparison across SARS-CoV-2 vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing neutralizing antibodies against SARS-CoV-2.
Paola Rogliani, Alfredo Chetta, Mario Cazzola, Luigino Calzetta   +3 more
doaj   +1 more source

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Nature Genetics, 2018
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we define 279 lung function signals, 139 of which are ...
N. Shrine, A. Guyatt, A. Erzurumluoglu, V. Jackson, B. Hobbs, C. Melbourne, C. Batini, K. Fawcett, Kijoung Song, P. Sakornsakolpat, Xingnan Li, Ruth Boxall, N. Reeve, M. Obeidat, J. Zhao, M. Wielscher, S. Weiss, K. Kentistou, J. Cook, B. Sun, Jian Zhou, J. Hui, S. Karrasch, M. Imboden, S. Harris, J. Marten, Stefan Enroth, S. Kerr, I. Surakka, V. Vitart, T. Lehtimäki, R. Allen, P. Bakke, T. Beaty, E. Bleecker, Y. Bossé, C. Brandsma, Zhengming Chen, J. Crapo, J. Danesh, D. Demeo, F. Dudbridge, R. Ewert, C. Gieger, A. Gulsvik, A. Hansell, K. Hao, Joshua D Hoffman, J. Hokanson, G. Homuth, P. Joshi, P. Joubert, C. Langenberg, Xuan Li, Liming Li, Kuang Lin, L. Lind, N. Locantore, J. Luan, A. Mahajan, J. Maranville, A. Murray, D. Nickle, R. Packer, M. Parker, Megan L. Paynton, D. Porteous, Dmitry Prokopenko, D. Qiao, R. Rawal, H. Runz, I. Sayers, D. Sin, Blair H. Smith, M. Soler Artigas, D. Sparrow, R. Tal-Singer, P. Timmers, M. van den Berge, J. Whittaker, P. Woodruff, L. Yerges-Armstrong, O. Troyanskaya, O. Raitakari, M. Kähönen, O. Polašek, U. Gyllensten, I. Rudan, I. Deary, N. Probst-Hensch, H. Schulz, A. James, James F. Wilson, B. Stubbe, E. Zeggini, M. Jarvelin, N. Wareham, E. Silverman, C. Hayward, A. Morris, A. Butterworth, R. Scott, R. Walters, D. Meyers, M. Cho, D. Strachan, I. Hall, M. Tobin, L. Wain   +108 more
semanticscholar   +1 more source

Impaired Lung Function, Lung Disease, and Risk of Incident Dementia.

American Journal of Respiratory and Critical Care Medicine, 2019
Rationale: Growing evidence suggests that compromised lung health may be linked to dementia and worsening cognitive ability. Objectives: To test the hypothesis that impaired lung function or lung disease in midlife is associated with greater risk of ...
P. Lutsey, N. Chen, M. Mirabelli, K. Lakshminarayan, D. Knopman, Keith A. Vossel, R. Gottesman, T. Mosley, Á. Alonso   +8 more
semanticscholar   +1 more source

Mycophenolate Mofetil Improves Exercise Tolerance in Systemic Sclerosis Patients with Interstitial Lung Disease: A Pilot Study

Rheumatology and Therapy, 2020
Introduction Systemic sclerosis (SSc) is an autoimmune disease characterized by the overproduction of collagen leading to fibrosis of the skin and internal organs.
Valentina Vaiarello, Stefano Schiavetto, Federica Foti, Antonietta Gigante, Francesco Iannazzo, Gregorino Paone, Paolo Palange, Edoardo Rosato   +7 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study

BMC Pediatrics
Background Persistent airflow limitation (PAL) in childhood asthma is associated with a poor prognosis. The aim of this study was to categorize asthmatic children with PAL into distinct phenotypes and investigate the risk factors associated with each ...
Shiqiu Xiong, Xinyu Jia, Wei Chen, Chuanhe Liu   +3 more
doaj   +1 more source

Respiratory sleep disturbance in children and adolescents with cystic fibrosis

Revista Portuguesa de Pneumologia (English Edition), 2016
Sleep disturbance has been described in cystic fibrosis (CF) patients as relevant to clinical and lung function predictive factors helping to improve the diagnosis and early intervention. Related paediatric studies are scarce.
A.M. Silva, A. Descalço, M. Salgueiro, L. Pereira, C. Barreto, T. Bandeira, R. Ferreira   +6 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

International consensus on lung function testing during the COVID-19 pandemic and beyond

ERJ Open Research, 2022
Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing.
Aisling McGowan, Pierantonio Laveneziana, Sam Bayat, Nicole Beydon, P.W. Boros, Felip Burgos, Matjaž Fležar, Monika Franczuk, Maria-Alejandra Galarza, Adrian H. Kendrick, Enrico Lombardi, Jellien Makonga-Braaksma, Meredith C. McCormack, Laurent Plantier, Sanja Stanojevic, Irene Steenbruggen, Bruce Thompson, Allan L. Coates, Jack Wanger, Donald W. Cockcroft, Bruce Culver, Karl Sylvester, Frans De Jongh   +22 more
doaj   +1 more source

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya, Veronica Moroz, Juliet Hale, Vesna Pavasovic, Rachel Hobson, Patricia Sartori, Daniel Saunders, Mark Powis, Gordan M. Vujanic, Stephen Baker, Kathy Pritchard‐Jones   +10 more
wiley   +1 more source