Results 101 to 110 of about 219,832 (311)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Left pulmonary vein anatomical variation in Turner syndrome. Benefits of three‐dimensional visualization for surgical planning

Thoracic Cancer
A 41 year‐old female with a medical history of Turner syndrome underwent a chest computed tomography (CT) scan which revealed a varicose left pulmonary vein and an endobronchial tumor of the left lower lobe.
Gabrielle Drevet, Valentin Soldea, François Tronc   +2 more
doaj   +1 more source

Succinylation heterogeneity in lung adenocarcinoma: from prognostic model to KLK6-driven tumor microenvironment remodeling

Frontiers in Immunology
BackgroundLung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality. Protein succinylation, a key post-translational modification, is implicated in tumor progression.
Jichang Liu, Xuehan Zhu, Chenlong Zha, Jiaqi Ding, Chuanpeng Zhang, Yizhe Wang, Tao Yan, Hui Kong, Yong Liu, Jingyu Chen, Jingyu Chen   +10 more
doaj   +1 more source

Baseline 6-Min Walk Distance Predicts Survival in Lung Transplant Candidates

, 2008
Tereza Martinu, Michael A. Babyak, C.F. O’Connell, Robert M. Carney, Elbert P. Trulock, R. Duane Davis, James A. Blumenthal, Scott M. Palmer   +7 more
openalex   +1 more source

Outcomes of novel surgical procedures for graft size mismatch in living-donor lobar lung transplantation [PDF]

, 2020
Daisuke Nakajima, Satona Tanaka, Akihiro Ohsumi, Hiroshi Date   +3 more
openalex   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

The Lung Transplant Program in Saudi Arabia. Unique Differences and Challenges [PDF]

, 2014
Imran Nizami, Behram Khan
openalex   +1 more source

Nutritional intervention process for a patient with lung transplantation: a case report

, 2023
Dinh Phu Nguyen, Van-Anh Nguyen, Hao Dao Thi, Nguyen Thi Huong, Thao T Pham, Duyen Bui Thi, Nguyễn Thu Hà   +6 more
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

RNA binding protein ALYREF regulates ferroptosis to facilitate LUAD growth and metastasis via promoting SLC7A11 mRNA stability

Scientific Reports
Ferroptosis is of great significance in carcinogenesis as it interconnects with a multiplicity of biological processes. Meanwhile, its function and regulatory role in lung cancer remains ambiguous.
Yanni Chen, Ting Zhao, Hao Chen, Jun Chen, Weili Han   +4 more
doaj   +1 more source