Results 101 to 110 of about 214,416 (313)

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Identification of novel diagnostic and prognostic microRNAs in sarcoma on TCGA dataset: bioinformatics and machine learning approach

Scientific Reports
The discovery of unique microRNA (miR) patterns and their corresponding genes in sarcoma patients indicates their involvement in cancer development and suggests their potential use in medical management. MiRs were identified from The Cancer Genome Atlas (
Rahem Rahmati, Fatemeh Zarimeidani, Farnaz Ahmadi, Hannaneh Yousefi-Koma, Abdolreza Mohammadnia, Maryam Hajimoradi, Shadi Shafaghi, Elham Nazari   +7 more
doaj   +1 more source

Immunological Similarities and Differences between Post-COVID-19 Lung Sequelae and Idiopathic Pulmonary Fibrosis

Biomedicines
Introduction: Pulmonary fibrosis is an irreversible condition that may be caused by known (including viral triggers such as SARS-CoV-2) and unknown insults.
Sara Gangi, Laura Bergantini, Paolo Cameli, Irene Paggi, Marco Spalletti, Fabrizio Mezzasalma, Elena Bargagli, Miriana d’Alessandro   +7 more
doaj   +1 more source

Pathological findings following lung transplantation. [PDF]

, 1972
Κ.B. Shilkin, Lynne Reid
openalex   +1 more source

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang, Yuanhao Zhou, Qingyuan Wu, Yishu Li, Yilin Huang, Kexin Yu, Ping Li, Zhenye Lv, Haotian Liu, Hai Zou, Huiyu Liu, Xiaozhou Mou   +11 more
wiley   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

Diaphragm and Lung Transplantation

Transplant International
Mutual interactions between the diaphragm and lung transplantation (LTx) are known to exist. Before LTx, many factors can exert notable impact on the diaphragmatic function, such as the underlying respiratory disease, the comorbidities, and the chronic treatments of the patient.
Alessandro Palleschi, Alessandro Palleschi, Giovanni Mattioni, Giovanni Mattioni, Antonella LoMauro, Emilia Privitera, Valeria Musso, Letizia Morlacchi, Letizia Morlacchi, Maurizio Vergari, Daniele Velardo, Giacomo Grasselli, Giacomo Grasselli   +12 more
openaire   +4 more sources

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

Advanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma, Yang Chen, Qinfan Yao, Yuxi Wang, Nan Ouyang, Fei Han, Guzong Wang, Meifang Wang, Yuan Yuan, Jianghua Chen, Jianzhen Shan, Dajin Chen   +11 more
wiley   +1 more source

The Lung and Other Organs TRANSPLANTATION OF THE LUNG

, 1967
David A. Blumenstock
openalex   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source