Results 41 to 50 of about 18,170 (246)

PAK4 inhibition significantly potentiates Gemcitabine activity in PDAC cells via inhibition of Wnt/β-catenin, p-ERK/MAPK and p-AKT/PI3K pathways

Biochemistry and Biophysics Reports, 2023
Pancreatic Ductal Adenocarcinoma (PDAC) remains one of the most difficult to treat cancers. Gemcitabine is still the standard of care treatment for PDAC but with modest survival benefit and well reported resistance.
Charudatt Samant, Ramesh Kale, Anand Bokare, Mahip Verma, K. Sreedhara Ranganath Pai, Mandar Bhonde   +5 more
doaj   +1 more source

Effect of Ultrasound Application on Protein Yield and Fate of Alkaloids during Lupin Alkaline Extraction Process

Biomolecules, 2020
The objective of this work is to elucidate the fate of quinolizidine alkaloids (QA) during the lupin protein extraction process assisted with ultrasound and the evaluation of the nutritional and functional properties of the protein fraction.
Luis Alberto Aguilar-Acosta, S. Serna-Saldívar, J. Rodríguez-Rodríguez, Anayansi Escalante-Aburto, C. Chuck‐Hernández   +4 more
semanticscholar   +1 more source

Evaluation of the Major Seed Storage Proteins, the Conglutins, Across Genetically Diverse Narrow-Leafed Lupin Varieties

Frontiers in Nutrition, 2022
Lupin seeds have an excellent nutritional profile, including a high proportion of protein and dietary fiber. These qualities make lupin seeds an ideal candidate to help meet the growing global demand for complementary sources of protein.
Arineh Tahmasian, Arineh Tahmasian, Angéla Juhász, James A. Broadbent, Mitchell G. Nye-Wood, Thao T. Le, Michelle L. Colgrave, Michelle L. Colgrave   +7 more
doaj   +1 more source

Implementation of Machine Learning Models to Predict Functionality of Pea Flour From Its Composition

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives The goal of this research was to examine the relationship between the composition and functionality of pea flour using the following machine learning algorithms: linear regression, partial least squares regression (PLSR), Gaussian process regression (GPR), support vector regression, gradient‐boosted decision trees ...
Colten N. Nickerson, Sarah Hogarth, Andrea K. Stone, Gene C. Arganosa, Pankaj Bhowmik, Tom D. Warkentin, Jordan Ubbens, Michael T. Nickerson   +7 more
wiley   +1 more source

The Current Landscape of Nanopaclitaxel Formulations and the Benefits of Polymeric Micellar Paclitaxel in Solid Tumors

Indian Journal of Medical and Paediatric Oncology
The tumor microenvironment (TME) creates a complex biochemical and physical barrier affecting the penetration of chemotherapeutic agents into the tumor. Nanotherapy, which allows targeted drug delivery, has generated considerable interest in recent times
Vaibhav Choudhary, Nirmal Raut, Gajanan Panchal, Maneesha Khalse, Kamlesh Patel   +4 more
doaj   +1 more source

Contrasting CO2‐response strategies in Pardina lentils: Yield maximization in a commercial cultivar and seed composition adjustment in a landrace

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Assessing crop's responses to elevated carbon dioxide (eCO2) is crucial for global food security. This study examines the impact of eCO2 (700 μmol mol−1) on the cultivars of lentil (Lens culinaris), local Pardina Verde Rayada lentil (PVRL), and commercial Pardina lentil (PL) in terms of the productivity and nutritional composition ...
Mohammad Abdullah, Idoia Garmendia, Cristina Mallor, Nieves Goicoechea, Johann Martínez‐Lüscher   +4 more
wiley   +1 more source

Genomic resources for lupins are coming of age

Legume Science, 2021
Lupins are underutilised pulse crops subject to increasing interest for human consumption of the high‐protein grain. They are also valued as a source of animal nutrition and make an excellent break crop in agricultural production systems.
Lars G. Kamphuis, Gagan Garg, Rhonda Foley, Karam B. Singh   +3 more
doaj   +1 more source

Stereotipe Gender dalam Serial Drama Daughter of Lupin (2019)

Paradigma: Jurnal Kajian Budaya, 2021
Stereotypes shown by the media have influenced how society constructs their perspective on gender. Japanese television program that contained gender stereotypes is Daughter of Lupin (2019) drama series.
Nabila Vina Fairuzzahra
doaj   +1 more source

Benefits of a commercial solid-state fermentation (SSF) product on growth performance, feed efficiency and gut morphology of juvenile Nile tilapia (Oreochromis niloticus) fed different UK lupin meal cultivars

Aquaculture, 2020
A nutritional investigation was conducted to determine whether growth performance, feed efficiency and midgut morphology of Nile tilapia is affected by United Kingdom cultivars of Yellow Lupin (Control, Y) (YLC) or Blue Lupin (Control, B) (BLC ...
P. Bowyer, E. El‐Haroun, Heba S. Salim, S. Davies   +3 more
semanticscholar   +1 more source

Wilting wildflowers and bummed‐out bees: Climate change threatens US state symbols

People and Nature, EarlyView.
Abstract Species designated as state symbols in the United States carry cultural importance, embody historical heritage and maintain long‐standing linkages to Indigenous traditions. However, they are threatened by climate change and even face the risk of local or global extinction.
Xuezhen Ge, Ya Zou, Heather A. Hager, Jonathan A. Newman   +3 more
wiley   +1 more source