Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays [PDF]
, 2015 - Introduction: The aim of this study was to examine the prevalence and functional effects of antibodies directed against Factor (F)Xa and other serine proteases (SP) in patients with antiphospholipid syndrome (APS).
Artim-Esen, B. +8 more
core +2 more sources
Damage‐associated molecular patterns and coagulation
British Journal of Haematology, EarlyView.Injured cells release damage‐associated molecular patterns (DAMPs), which promote clot formation by activating coagulation, inflammation and immune pathways. Targeting these immunothrombotic mechanisms, via DAMPs, offers new opportunities for diagnosis and therapy in thromboinflammatory disease.
Jun Yong, Cheng‐Hock Toh
wiley +1 more source
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study. [PDF]
, 2015 Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy.
Arenas-Pinto, A +5 more
core +1 more source
Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
Clinical Endocrinology, EarlyView.ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley +1 more source
Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis
Arthritis Research & Therapy, 2019 Objective This study evaluates the utility of urinary pro-thrombotic molecules such as tissue factor (TF), anti-thrombotic molecules such as tissue factor pathway inhibitor (TFPI), and fibrinolytic molecules such as plasmin and d-dimer as biomarkers of ...
Ling Qin +10 more
doaj +1 more source
Pathogenetically differentiated management of pregnancy in patients with retrochorial hematoma
Акушерство, гинекология и репродукция, 2020 Introduction. Intrauterine hematomas commonly found in routine ultrasound examinations represent one of causes resulting in early pregnancy loss.
Kh. G. Sultangadzhieva, J. Kh. Khizroeva
doaj +1 more source
Recent Progress in Double Filtration Plasmapheresis
Hemodialysis International, EarlyView.ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li +3 more
wiley +1 more source
Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]
, 2000 Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N. +5 more
core +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source