Results 61 to 70 of about 19,610 (201)

Interference of lupus anticoagulant causing antiprothrombin and anti–beta-2-glycoprotein I antibodies on international normalized ratio measurements: comparative analysis of international normalized ratio methods

Research and Practice in Thrombosis and Haemostasis
Background: Life-long vitamin K antagonist (VKA) therapy is recommended as a standard of care in antiphospholipid syndrome (APS) patients with thrombosis.
Rachel Gehlen, Roxanne G. Moesbergen, CuiCui Bai, Philip G. de Groot, A.J.Gerard Jansen, Joost C.M. Meijers, Bas de Laat, Jasper A. Remijn   +7 more
doaj   +1 more source

Acquired Hemophilia in a Patient With Rheumatoid Arthritis: Case Report and Literature Review

Clinical Management Issues, 2018
Acquired hemophilia (AH) is a rare bleeding disorder caused by the spontaneous development of autoantibodies against coagulation factors, most commonly factor (F) VIII (acquired hemophilia A, AHA).
Masen Abdel Jaber, Roberto Bortolotti, Sara Martinelli, Mara Felicetti, Teresa Aloisi, Giuseppe Paolazzi   +5 more
doaj   +1 more source

Acquired inhibitors of blood coagulation: diagnostic perpective and especial cases [PDF]

, 2016
Los inhibidores adquiridos son defectos raros. Se asocian a diferentes manifestaciones clínicas con morbimortalidad significativa. Su detección es importante para implementar el tratamiento sin demora.
Blanco, Alicia Noemi, Grosso, Silvia Haydée, Ingratti, Marcelo Francisco, Lazzari, María Ángela, Meschengieser, Carolina, Morandini, Maria Paula, Remotti, Lucia, Sánchez Luceros, Analía Gabriela, Woods, Adriana Inés   +8 more
core  

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Anticorpos antinucleossomo e síndrome antifosfolipídica: estudo observacional Antinucleosome antibodies and primary antiphospholipid syndrome: an observational study

Revista Brasileira de Reumatologia, 2012
OBJETIVO: Avaliar a associação entre a presença de anticorpos antinucleossomo (anti-NCS) e a síndrome antifosfolipídica primária (SAFP) e o posterior desenvolvimento de lúpus eritematoso sistêmico (LES).
Alexandre Wagner Silva de Souza, Silene Peres Keusseyan, Neusa Pereira da Silva, Emilia Inoue Sato, Luis Eduardo Coelho Andrade   +4 more
doaj   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

The Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk, Joost H. N. Schuitemaker, Marijke M. Faas, Alexandra M. Smink   +3 more
wiley   +1 more source

36-Year-Old Female with Catastrophic Antiphospholipid Syndrome Treated with Eculizumab: A Case Report and Review of Literature

Case Reports in Hematology, 2014
Catastrophic antiphospholipid syndrome (CAPS) is a rare but potentially life-threatening condition characterized by diffuse vascular thrombosis, leading to multiple organ failure developing over a short period of time in the presence of positive ...
Marianna Strakhan, Mariana Hurtado-Sbordoni, Nahun Galeas, Kamila Bakirhan, Karenza Alexis, Tarek Elrafei   +5 more
doaj   +1 more source

Type I Interferon Gene Expression and Its Association With Ocular Involvement in Systemic Lupus Erythematosus

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Severalstudies have highlighted the role of Type I interferons (IFN‐I) in activating inflammatory pathways in lupus. However, no previous research focused on investigating the role of IFN‐I gene expression in the ophthalmologic involvement of systemic lupus erythematosus (SLE).
Raphael Teixeira Costa, Werbson Lima Guaraná, Braziliano Miguel da Silva Júnior, Jaciel Clementino, Luís Sousa Inês, Paula Sandrin‐Garcia, Thiago Sotero Fragoso   +6 more
wiley   +1 more source

Antiphosphatidylserine antibody as a cause of multiple dural venous sinus thromboses and ST-elevation myocardial infarction [PDF]

, 2018
Objective: Rare disease Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antibodies directed against phos-pholipids on plasma membranes. Through unclear mechanisms, APS confers hypercoagulability.
Marquardt, Caillin W., Pickens, Peter V., Varner, Chelsea K.   +2 more
core   +1 more source

Tissue factor in antiphospholipid antibody-induced pregnancy loss:a pro-inflammatory molecule [PDF]

, 2008
Fetal loss in patients with antiphospholipid antibodies (aPL) has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically complement activation with generation of the anaphylotoxin C5a, is an essential ...
Broze GJ Jr., de Prost D, G Girardi, Ikeda K, Kornberg A, Macfarlane SR, Makrides SC, Monestier M, N Mackman, Pawlinski R, Randolph GJ, Shin ML   +11 more
core   +2 more sources