Results 71 to 80 of about 9,755 (173)

PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins?

Bleeding, Thrombosis and Vascular Biology
Background and Aims: Plasma mixing test is a simple laboratory procedure, which is performed on samples from patients with coagulation screening tests prolonged (mainly the activated partial thromboplastin (APTT), but also the prothrombin time (PT) or ...
doaj   +1 more source

Patients with DVT and primary antiphospholipid syndrome have worse obstetric outcomes than pregnant women with DVT and negative antiphospholipid antibodies: a retrospective cohort study

São Paulo Medical Journal
BACKGROUND: Pregnant women are at an increased risk of thromboembolism compared with non-pregnant women. Venous thrombosis is a manifestation of antiphospholipid syndrome (APS), an autoimmune thrombophilia associated with pregnancy morbidity. OBJECTIVES:
Priscila Guyt Rebelo, Marcela Ignacchiti Lacerda Ávila, Nilson Ramires de Jesús, Flávio Victor Signorelli, Evandro Mendes Klumb, Guilherme Ramires de Jesús   +5 more
doaj   +1 more source

Seizure as an Atypical Presentation of Myasthenia Gravis: A Rare but Critical Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT A 27‐year‐old male patient with a known case of epilepsy and also recently diagnosed with myasthenia gravis presented with dysphagia, respiratory distress, and seizures. Despite timely intervention, he progressed into septic shock during a myasthenic crisis and succumbed to cardiopulmonary arrest.
Huda Faisal, Chanchan, Karan Chaman Lal, Zahabia Adnan, Shamyl Zehra, MD. Faisal Ahmed   +5 more
wiley   +1 more source

NEWLY DIAGNOSED HEREDITARY FACTOR V DEFICIENCY IN A PATIENT PRESENTING WITH DEEP VEIN THROMBOSIS: A Rare Case

Hematology, Transfusion and Cell Therapy
Objective: Factor V (FV) is a crucial regulator of hemostasis, functioning as both a procoagulant and an anticoagulant glycoprotein within the coagulation cascade. In plasma, FV exists as an inactive precursor, which is activated by thrombin or factor Xa
Songül Beskisiz Dönen, Vehbi Demircan, Abdullah Karakuş, Mehmet Orhan Ayyıldız   +3 more
doaj   +1 more source

Factor XIII Deficiency: A Silent Bleeder Behind a Normal Coagulation Profile

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Factor XIII deficiency is a rare cause of bleeding disorder. An 8‐month‐old male infant presented with persistent bleeding from a minor lip cut injury, which was sustained 2 days prior. The bleeding did not stop despite local hemostatic measures.
Ramesh Yadav, Madhav Raj Karki, Dikshya Pokhrel, Aron Neupane, Kshitiz Parajuli, Hem Sagar Rimal   +5 more
wiley   +1 more source

PO78 | Acquired hemophilia A as a paraneoplastic syndrome: two cases report on a rare coexistence

Bleeding, Thrombosis and Vascular Biology
Background: Acquired hemophilia, meanwhile, is the most common acquired disease affecting clotting factors. Possible causes that have been empirically described include autoimmune disease (such as rheumatoid arthritis or systemic lupus erythematosus ...
doaj   +1 more source

ACQUIRED HEMOPHILIA A IN A 3-YEAR-OLD PEDIATRIC PATIENT: A CASE REPORT OF RARE AND POTENTIALLY FATAL BLEEDING DISORDER

Hematology, Transfusion and Cell Therapy
Introduction: Acquired hemophilia A (AHA) is a rare severe autoimmune bleeding disorder with significant morbidity and mortality mainly occurring in older adults (average age 75). The condition is extremely rare in children.
Z Alrajhi, LLE Souza, M Carcao
doaj   +1 more source

Granulomatosis With Polyangiitis Presenting as Deep Vein Thrombosis in an Adolescent: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Granulomatosis with polyangiitis can rarely present as deep vein thrombosis in adolescents. Unexplained thrombosis in a young patient, accompanied by systemic inflammatory features, should raise suspicion for an underlying vasculitis. Early recognition and prompt initiation of immunosuppressive therapy alongside anticoagulation are crucial to ...
Bishal Budha, Aron Shrestha, Satish Bajracharya, Dhiraj Poudel, Bishweshar Joshi, Pujan Pandey, Rajan Budha, Sadikshya Pandey, Bishal Panthi   +8 more
wiley   +1 more source

Inflammation in Idiopathic Intracranial Hypertension: An Immunometabolic Mechanistic Framework and Clinical Implications

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Systemic metabolic dysfunction and comorbidities may act as upstream modulators converging on inflammatory activation, which is closely intertwined with excessive CSF production and impaired clearance, potentially contributing to sustained ICP elevation.
Guangyu Han, Jiahao Song, Shuling Wan, Xunming Ji, Da Zhou, Ran Meng   +5 more
wiley   +1 more source

Decreasing Serum Adropin Levels in Patients With Systemic Lupus Erythematosus: A Case‐Control Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Introduction Systematic lupus erythematosus is a complex fundamental autoimmune disease with relapsing‐remitting course and spectrum of disease ranging from mild to life‐threatening illness. Approximately half of women diagnosed with systemic lupus erythematosus (SLE) are affected by obesity, with rates reaching up to 50%.
Mehrzad Hajialilo, Amir Ghorbanihaghjo, Kamran Javidi‐Aghdam, Seyed Amir Hossein Seyeddorraji, Alireza Khabbazi, Mehdi Jafarpour   +5 more
wiley   +1 more source