Results 1 to 10 of about 155,199 (206)
Lupus Science and Medicine, 2023 Objective To assess the efficacy of anifrolumab, a type-1 interferon receptor subunit-1 monoclonal antibody, in treating refractory cutaneous lupus erythematosus (CLE) and lupus non-specific mucocutaneous manifestations in patients with systemic lupus ...
Aaron Bao, M. Petri, A. Fava, Jun Kang
semanticscholar +3 more sources
Acta Dermato-Venereologica, 2022 NLRP3 inflammasome is suggested to contribute to the complex pathogenesis of systemic lupus erythematosus, but its role in cutaneous lupus erythematosus has not been addressed.
Katariina Mähönen +6 more
semanticscholar +3 more sources
A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus
Frontiers in Immunology, 2022 Lupus erythematosus is an autoimmune disease that may manifest in a variety of organs and tissues including the skin, kidney, brain, heart and lung. Many patients present with cutaneous lupus, where disease is often limited to the skin, but are at risk ...
P. Curtiss, A. Walker, B. Chong
semanticscholar +3 more sources
Frontiers in Immunology, 2021 Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic lupus erythematosus (SLE), and CLE can also develop in the absence of ...
Lisa Abernathy-Close +14 more
semanticscholar +3 more sources
Cutaneous Lupus Erythematosus [PDF]
JAMA Dermatology, 2014 Lupus erythematosus is an autoimmune disease that presents with either cutaneous or systemic findings. Cutaneous lupus is divided into lupus-specific and -nonspecific skin disease with the former including the acute cutaneous lupus, subacute cutaneous lupus, and chronic cutaneous lupus subtypes. Patients with cutaneous lupus must be evaluated regularly
A Brooke, Eastham, Ruth Ann, Vleugels
openaire +3 more sources
Cutaneous Lupus Erythematosus: An Update on Pathogenesis and Future Therapeutic Directions
American Journal of Clinical Dermatology, 2023 Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus erythematosus [CLE]).
D. Niebel +4 more
semanticscholar +1 more source
Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus.
New England Journal of Medicine, 2022 BACKGROUND Blood dendritic cell antigen 2 (BDCA2) is a receptor that is exclusively expressed on plasmacytoid dendritic cells, which are implicated in the pathogenesis of lupus erythematosus.
V. Werth +18 more
semanticscholar +1 more source
Single-cell sequencing shows cellular heterogeneity of cutaneous lesions in lupus erythematosus
Nature Communications, 2022 Discoid lupus erythematosus (DLE) and systemic lupus erythematosus (SLE) are both types of lupus, yet the characteristics, and differences between them are not fully understood.
Meiling Zheng +16 more
semanticscholar +1 more source
Cutaneous Involvement in Systemic Lupus Erythematosus: A Review for the Rheumatologist
Journal of Rheumatology, 2022 The majority of patients with systemic lupus erythematosus (SLE) have cutaneous manifestations at some point in their disease course. The skin findings in SLE are classified as SLE-specific or SLE-nonspecific based on histopathologic findings.
C. Stull, G. Sprow, V. Werth
semanticscholar +1 more source
Cutaneous Manifestations of “Lupus”: Systemic Lupus Erythematosus and Beyond
International Journal of Rheumatology, 2021 Lupus, Latin for “wolf,” is a term used to describe many dermatologic conditions, some of which are related to underlying systemic lupus erythematosus, while others are distinct disease processes.
Elizabeth E Cooper +2 more
semanticscholar +1 more source