Results 1 to 10 of about 136,700 (260)

Case series of anifrolumab for treatment of cutaneous lupus erythematosus and lupus-related mucocutaneous manifestations in patients with SLE

open access: yesLupus Science and Medicine, 2023
Objective To assess the efficacy of anifrolumab, a type-1 interferon receptor subunit-1 monoclonal antibody, in treating refractory cutaneous lupus erythematosus (CLE) and lupus non-specific mucocutaneous manifestations in patients with systemic lupus ...
Jun Kang, Aaron Bao
doaj   +2 more sources

Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus

open access: yesActa Dermato-Venereologica, 2022
NLRP3 inflammasome is suggested to contribute to the complex pathogenesis of systemic lupus erythematosus, but its role in cutaneous lupus erythematosus has not been addressed.
Katariina Mähönen   +6 more
doaj   +2 more sources

A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus

open access: yesFrontiers in Immunology, 2022
Lupus erythematosus is an autoimmune disease that may manifest in a variety of organs and tissues including the skin, kidney, brain, heart and lung. Many patients present with cutaneous lupus, where disease is often limited to the skin, but are at risk ...
Paul Curtiss   +2 more
doaj   +2 more sources

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

open access: yesFrontiers in Immunology, 2021
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic lupus erythematosus (SLE), and CLE can also develop in the absence of ...
Lisa Abernathy-Close   +18 more
doaj   +2 more sources

Cutaneous lupus erythematosus: An update [PDF]

open access: yesIndian Dermatology Online Journal, 2014
Lupus erythematosus (LE) is a chronic, autoimmune, multisystem disease that displays many diverse symptoms in which localized cutaneous LE (CLE) is on one end of the spectrum and severe systemic LE (SLE) on the other end.
Carina M Grönhagen, Filippa Nyberg
doaj   +3 more sources

Lupus Erythematosus: Cutaneous Manifestations and Treatment

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2019
Cutaneous lupus erythematosus (CLE) includes a broad range of dermatologic manifestations, which may or may not be associated with systemic manifestations. Specific CLE - defined by the presence of an interface dermatitis on histopathological evaluation -
Francisca Alves, Margarida Gonçalo
doaj   +2 more sources

Skin involvement in systemic lupus erythematosus: a review article [PDF]

open access: yesRomanian Journal of Rheumatology, 2023
Cutaneous disease is one of the most frequent manifestations of systemic lupus erythematosus (SLE), being classified as LE-specific and LE-nonspecific.
Teodora Baciu   +7 more
doaj   +1 more source

Cutaneous Lupus Erythematosus [PDF]

open access: yesJAMA Dermatology, 2014
Lupus erythematosus is an autoimmune disease that presents with either cutaneous or systemic findings. Cutaneous lupus is divided into lupus-specific and -nonspecific skin disease with the former including the acute cutaneous lupus, subacute cutaneous lupus, and chronic cutaneous lupus subtypes. Patients with cutaneous lupus must be evaluated regularly
Ruth Ann Vleugels, A. Brooke Eastham
openaire   +5 more sources

Panoramic view of clinical features of lupus erythematosus: a cross-sectional multicentre study from China

open access: yesLupus Science and Medicine, 2023
Objective Lupus erythematosus (LE) is a complicated disease with highly heterogeneous clinical manifestations. Previous studies have rarely included all subgroups of patients with lupus and have overlooked the importance of the cutaneous manifestations ...
Qing Zhang   +19 more
doaj   +1 more source

Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho   +6 more
doaj   +1 more source

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