Results 11 to 20 of about 166,181 (302)

Cutaneous lupus erythematosus: a review of etiopathogenic, clinical, diagnostic and therapeutic aspects

open access: yesAnais Brasileiros de Dermatologia, 2023
Cutaneous lupus erythematosus is an autoimmune disease of varied clinical expression, which may present as an exclusively cutaneous disease or be one of the multiple manifestations of systemic lupus erythematosus.
Everton Carlos Siviero do Vale   +1 more
doaj   +1 more source

Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Blood dendritic cell antigen 2 (BDCA2) is a receptor that is exclusively expressed on plasmacytoid dendritic cells, which are implicated in the pathogenesis of lupus erythematosus.
V. Werth   +18 more
semanticscholar   +1 more source

Single-cell sequencing shows cellular heterogeneity of cutaneous lesions in lupus erythematosus

open access: yesNature Communications, 2022
Discoid lupus erythematosus (DLE) and systemic lupus erythematosus (SLE) are both types of lupus, yet the characteristics, and differences between them are not fully understood.
Meiling Zheng   +16 more
semanticscholar   +1 more source

Cutaneous Involvement in Systemic Lupus Erythematosus: A Review for the Rheumatologist

open access: yesJournal of Rheumatology, 2022
The majority of patients with systemic lupus erythematosus (SLE) have cutaneous manifestations at some point in their disease course. The skin findings in SLE are classified as SLE-specific or SLE-nonspecific based on histopathologic findings.
C. Stull, G. Sprow, V. Werth
semanticscholar   +1 more source

Cutaneous Manifestations of “Lupus”: Systemic Lupus Erythematosus and Beyond

open access: yesInternational Journal of Rheumatology, 2021
Lupus, Latin for “wolf,” is a term used to describe many dermatologic conditions, some of which are related to underlying systemic lupus erythematosus, while others are distinct disease processes.
Elizabeth E Cooper   +2 more
semanticscholar   +1 more source

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

open access: yes, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana   +5 more
core   +6 more sources

Ocular discoid lupus erythematosus: More than what meets the eye

open access: yesIndian Dermatology Online Journal, 2023
Lupus erythematosus is a spectrum that includes auto-immune disorders such as systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus (SCLE), and chronic cutaneous lupus erythematosus (CCLE).
Sumiti Pareek   +3 more
doaj   +1 more source

Induction and exacerbation of subacute cutaneous lupus erythematosus following mRNA‐based or adenoviral vector‐based SARS‐CoV‐2 vaccination

open access: yesClincal and Experimental Dermatology, 2021
Evidence is accumulating that COVID‐19 vaccines might induce or exacerbate autoimmune rheumatic diseases. The currently available COVID‐19 vaccines include mRNA and recombinant adenoviral vector vaccines, both encoding SARS‐CoV‐2 spike protein production
A. Kreuter   +5 more
semanticscholar   +1 more source

Linear cutaneous lupus erythematosus in children—report of two cases and review of the literature: A case report

open access: yesSAGE Open Medical Case Reports, 2020
Linear cutaneous lupus erythematosus is an unusual presentation of cutaneous lupus following Blaschko’s lines. It is described mostly in children and young adults and is usually not associated with systemic involvement.
Darosa Lim   +3 more
doaj   +1 more source

Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2020
Manifestations of chronic cutaneous lupus erythematosus are variable. Periorbital and facial swelling occurs in dermatomyositis and systemic lupus, but it has been rarely reported as a manifestation of exclusively cutaneous lupus.
Mónica García-Arpa   +4 more
doaj   +1 more source

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