Results 41 to 50 of about 4,988 (293)

LuxS signaling in Porphyromonas gingivalis-host interactions [PDF]

, 2015
Dental plaque is a multispecies biofilm in the oral cavity that significantly influences oral health. The presence of the oral anaerobic pathogen Porphyromonas gingivalis is an important determinant in the development of periodontitis.
Crielaard, W., Lamont, R.J., Krom, B.P.; id_orcid, Krom, B.P., Scheres, N.   +4 more
core   +1 more source

Structural and Functional Characterization of the Signaling Molecule Autoinducer-2 Synthesis Enzyme S-Ribosylhomocysteinase in Limosilactobacillus fermentum [PDF]

Shipin Kexue
S-ribosylhomocysteinase (also referred to as LuxS protein) is an important enzyme involved in the biosynthesis of autoinducer-2 (AI-2) as a signaling molecule.
WEI Guangqiang, WANG Teng, XU Ziqi, WANG Yuzhu, ZHANG Wenbin, LI Xinglun, HUANG Aixiang
doaj   +1 more source

The absence of luxS reduces the invasion of Avibacterium paragallinarum but is not essential for virulence

Frontiers in Veterinary Science
The contagious respiratory pathogen, Avibacterium paragallinarum, contributes to infectious coryza in poultry. However, commercial vaccines have not shown perfect protection against infectious coryza.
Donghai Li, Donghai Li, Caiyun Huo, Guiping Li, Menghan Zhu, Fuzhou Xu, Jian Qiao, Huiling Sun   +7 more
doaj   +1 more source

Effect of Commiphora myrrha Extract on Biofilm Formation of Lactobacillus Isolated from Teeth Caries

Medical Journal of Babylon
Background: Dental caries starts, progresses, and results in tooth decay due to biological factors such as cariogenic bacteria. Streptococcus mutans and Lactobacillus are considered to be the main microorganisms involved in this condition. Objectives: To
Fatima Mohammed Jabbar, Sanaa Rahman Oleiwi   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Identification of genes regulated by cold temperature - a study of mdtJI in E. coli O157:H7 [PDF]

, 2009
E. coli O157:H7, a serious food-borne pathogen, is capable of adapting to distinctly different environments, ranging from the ruminant, to soil and water.
Urlich, Shelley
core  

Luxe

Anthropen, 2020
Le luxe reflète l’effort permanent de l’humain pour s’émanciper de la sphère du besoin, tout en stimulant l’innovation dans les styles de consommation et les formes de vie. Plus qu’un simple artefact, l’objet précieux porte en lui une part d’immatériel ; il condense un ensemble d’univers de sens et de relations.
openaire   +1 more source

LUX trigger efficiency [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018
31 pages, 14 ...
Akerib, D.S., Alsum, S., Araújo, H.M., Bai, X., Balajthy, J., Beltrame, P., Bernard, E.P., Bernstein, A., Biesiadzinski, T.P., Boulton, E.M., Boxer, B., Brás, P., Burdin, S., Byram, D., Carmona-Benitez, M.C., Chan, C., Cutter, J.E., Davison, T.J.R., Druszkiewicz, E., Fallon, S.R., Fan, A., Fiorucci, S., Gaitskell, R.J., Genovesi, J., Ghag, C., Gilchriese, M.G.D., Grace, E., Gwilliam, C., Hall, C.R., Haselschwardt, S.J., Hertel, S.A., Hogan, D.P., Horn, M., Huang, D.Q., Ignarra, C.M., Jacobsen, R.G., Ji, W., Kamdin, K., Kazkaz, K., Khaitan, D., Knoche, R., Korolkova, E.V., Kravitz, S., Kudryavtsev, V.A., Lenardo, B.G., Lesko, K.T., Liao, J., Lin, J., Lindote, A., Lopes, M.I., Manalaysay, A., Mannino, R.L., Marangou, N., Marzioni, M.F., McKinsey, D.N., Mei, D.-M., Moongweluwan, M., Morad, J.A., Murphy, A.S.J., Nehrkorn, C., Nelson, H.N., Neves, F., Oliver-Mallory, K.C., Palladino, K.J., Pease, E.K., Rischbieter, G.R.C., Rhyne, C., Rossiter, P., Shaw, S., Shutt, T.A., Silva, C., Solmaz, M., Solovov, V.N., Sorensen, P., Sumner, T.J., Szydagis, M., Taylor, D.J., Taylor, W.C., Tennyson, B.P., Terman, P.A., Tiedt, D.R., To, W.H., Tripathi, M., Tvrznikova, L., Utku, U., Uvarov, S., Velan, V., Verbus, J.R., Webb, R.C., White, J.T., Whitis, T.J., Witherell, M.S., Wolfs, F.L.H., Woodward, D., Xu, J., Yazdani, K., Zhang, C.   +96 more
openaire   +9 more sources

Position reconstruction in LUX [PDF]

Journal of Instrumentation, 2018
30 pages, 17 ...
LUX Collaboration, Akerib, D. S., Alsum, S., Araújo, H. M., Bai, X., Bailey, A. J., Balajthy, J., Beltrame, P., Bernard, E. P., Bernstein, A., Biesiadzinski, T. P., Boulton, E. M., Brás, P., Byram, D., Cahn, S. B., Carmona-Benitez, M. C., Chan, C., Currie, A., Cutter, J. E., Davison, T. J. R., Dobi, A., Druszkiewicz, E., Edwards, B. N., Fallon, S. R., Fan, A., Fiorucci, S., Gaitskell, R. J., Genovesi, J., Ghag, C., Gilchriese, M. G. D., Hall, C. R., Hanhardt, M., Haselschwardt, S. J., Hertel, S. A., Hogan, D. P., Horn, M., Huang, D. Q., Ignarra, C. M., Jacobsen, R. G., Ji, W., Kamdin, K., Kazkaz, K., Khaitan, D., Knoche, R., Larsen, N. A., Lenardo, B. G., Lesko, K. T., Lindote, A., Lopes, M. I., Manalaysay, A., Mannino, R. L., Marzioni, M. F., McKinsey, D. N., Mei, D. M., Mock, J., Moongweluwan, M., Morad, J. A., Murphy, A. St. J., Nehrkorn, C., Nelson, H. N., Neves, F., O'Sullivan, K., Oliver-Mallory, K. C., Palladino, K. J., Pease, E. K., Rhyne, C., Shaw, S., Shutt, T. A., Silva, C., Solmaz, M., Solovov, V. N., Sorensen, P., Sumner, T. J., Szydagis, M., Taylor, D. J., Taylor, W. C., Tennyson, B. P., Terman, P. A., Tiedt, D. R., To, W. H., Tripathi, M., Tvrznikova, L., Uvarov, S., Velan, V., Verbus, J. R., Webb, R. C., White, J. T., Whitis, T. J., Witherell, M. S., Wolfs, F. L. H., Xu, J., Yazdani, K., Young, S. K., Zhang, C.   +93 more
openaire   +6 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source